tacrolimus and its Impurities

A macrolide lactone, Tacrolimus is an immunosupressant drug. Tacrolimus is a macrolide calcineurin inhibitor used mainly after allogeneic organ transplant to lower the risk of organ rejection. Topical ointment is used to treat severe cases of atopic dermatitis (eczema)Reference standards of Tacrolimus API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

Displaying 69 results for tacrolimus Impurities
Drug Reference Standards & Impurity Synthesis in India
PA 20 67000

Tacrolimus

Tacrolimus


  • Catalogue No.:PA 20 67000

  • CAS :

    104987-11-3

  • Molecular Formula : C44H69NO12

  • Molecular Weight : 804.02

Drug Reference Standards & Impurity Synthesis in India
PA 20 01520

Tacrolimus Open Ring

Tacrolimus Open Ring


  • Catalogue No.:PA 20 01520

  • CAS :

    144432-23-5

  • Molecular Formula : C44H71NO13

  • Molecular Weight : 822.05

Drug Reference Standards & Impurity Synthesis in India
PA 20 01530

19-Epi Ascomycin

19-Epi Ascomycin


  • Catalogue No.:PA 20 01530

  • CAS :

    NA

  • Molecular Formula : C43H69NO12

  • Molecular Weight : 792.01

Drug Reference Standards & Impurity Synthesis in India
PA 20 01550

(E/Z)-FK-506 26,28-Allylic Ester Rearrangement Impurity

(E/Z)-FK-506 26,28-Allylic Ester Rearrangement Impurity


  • Catalogue No.:PA 20 01550

  • CAS :

    131944-48-4

  • Molecular Formula : C44H69NO12

  • Molecular Weight : 804.04

Drug Reference Standards & Impurity Synthesis in India
PA 20 01560

Tacrolimus Diene

Tacrolimus Diene


  • Catalogue No.:PA 20 01560

  • CAS :

    104987-16-8

  • Molecular Formula : C44H67NO11

  • Molecular Weight : 786

Drug Reference Standards & Impurity Synthesis in India
PA 20 01570

15-O-Desmethyl Tacrolimus

15-O-Desmethyl Tacrolimus


  • Catalogue No.:PA 20 01570

  • CAS :

    151039-41-7

  • Molecular Formula : C43H67NO12

  • Molecular Weight : 789.99

Drug Reference Standards & Impurity Synthesis in India
PA 20 01580

Tacrolimus 31 DMT

Tacrolimus 31 DMT


  • Catalogue No.:PA 20 01580

  • CAS :

    127984-76-3

  • Molecular Formula : C43H67NO12

  • Molecular Weight : 789.99

Drug Reference Standards & Impurity Synthesis in India
PA 20 01590

Tacrolimus 13 DMT

Tacrolimus 13 DMT


  • Catalogue No.:PA 20 01590

  • CAS :

    132172-14-6

  • Molecular Formula : C43H67NO12

  • Molecular Weight : 789.99

Drug Reference Standards & Impurity Synthesis in India
PA 20 01600

Tacrolimus Hydroxy Acid Impurity

Tacrolimus Hydroxy Acid Impurity


  • Catalogue No.:PA 20 01600

  • CAS :

    1700657-83-5

  • Molecular Formula : C44H71NO13

  • Molecular Weight : 822.03

Drug Reference Standards & Impurity Synthesis in India
PA 20 01610

Tacrolimus Monohydrate - Impurity G

Tacrolimus compound II


  • Catalogue No.:PA 20 01610

  • CAS :

    144490-63-1

  • Molecular Formula : C44H69NO12

  • Molecular Weight : 804.04

Drug Reference Standards & Impurity Synthesis in India
PA 20 01620

Tacrolimus Lactone Isomer

Tacrolimus Lactone Isomer


  • Catalogue No.:PA 20 01620

  • CAS :

    134590-88-8

  • Molecular Formula : C44H69NO12

  • Molecular Weight : 804.02

Drug Reference Standards & Impurity Synthesis in India
PA 20 01630

Tacrolimus Methyl Acryl Aldehyde

Tacrolimus Methyl Acryl Aldehyde


  • Catalogue No.:PA 20 01630

  • CAS :

    109466-74-2

  • Molecular Formula : C11H18O3

  • Molecular Weight : 198.26

Drug Reference Standards & Impurity Synthesis in India
PA 20 01640

Tacrolimus 21-Carboxy Acid

Tacrolimus 21-Carboxy Acid


  • Catalogue No.:PA 20 01640

  • CAS :

    NA

  • Molecular Formula : C44H71NO13

  • Molecular Weight : 822.06

Drug Reference Standards & Impurity Synthesis in India
PA 20 01650

15,​19-​Epoxy-​3H-​pyrido[2,​1-​c]​[1,​4]​oxaazacyclotricosine​-​1,​7,​20,​21(4H,​23H)​-​tetrone, 5,​6,​8,​11,​12,​13,​14,​15,​16,​17,​18,​19,​24,​25,​26,​26a-​hexadecahydro-​5,​19-​dihydroxy-​3-​[2-​(4-​hydroxy-​3-​oxocyclohexyl)​-​1-​methylethenyl]​-​14,​16-​dimethoxy-​4,​10,​12,​18-​tetramethyl-​8-​(2-​propenyl)​-​, [3S-​[3R*[E(1S*,​4R*)​]​,​4S*,​5R*,​8S*,​9E,​12R*,​14R*,​15S*,​16R*,​18S*,​19S*,​26aR*]​]​

15,​19-​Epoxy-​3H-​pyrido[2,​1-​c]​[1,​4]​oxaazacyclotricosine​-​1,​7,​20,​21(4H,​23H)​-​tetrone, 5,​6,​8,​11,​12,​13,​14,​15,​16,​17,​18,​19,​24,​25,​26,​26a-​hexadecahydro-​5,​19-​dihydroxy-​3-​[2-​(4-​hydroxy-​3-​oxocyclohexyl)​-​1-​methylethenyl]​-​14,​16-​dimethoxy-​4,​10,​12,​18-​tetramethyl-​8-​(2-​propenyl)​-​, [3S-​[3R*[E(1S*,​4R*)​]​,​4S*,​5R*,​8S*,​9E,​12R*,​14R*,​15S*,​16R*,​18S*,​19S*,​26aR*]​]​


  • Catalogue No.:PA 20 01650

  • CAS :

    129039-81-2

  • Molecular Formula : C43H65NO12

  • Molecular Weight : 787.98

Drug Reference Standards & Impurity Synthesis in India
PA 20 01660

15,​19:20,​23-​Diepoxy-​3H-​pyrido[2,​1-​c]​[1,​4]​oxaazacyclotricosine​-​1,​7,​21(4H,​8H,​23H)​-​trione, 5,​6,​11,​12,​13,​14,​15,​16,​17,​18,​19,​20,​24,​25,​26,​26a-​hexadecahydro-​5,​19-​dihydroxy-​3-​[2-​(4-​hydroxy-​3-​methoxycyclohexyl)​-​1-​methylethenyl]​-​14,​16-​dimethoxy-​4,​10,​12,​18-​tetramethyl-​8-​(2-​propenyl)​

15,​19:20,​23-​Diepoxy-​3H-​pyrido[2,​1-​c]​[1,​4]​oxaazacyclotricosine​-​1,​7,​21(4H,​8H,​23H)​-​trione, 5,​6,​11,​12,​13,​14,​15,​16,​17,​18,​19,​20,​24,​25,​26,​26a-​hexadecahydro-​5,​19-​dihydroxy-​3-​[2-​(4-​hydroxy-​3-​methoxycyclohexyl)​-​1-​methylethenyl]​-​14,​16-​dimethoxy-​4,​10,​12,​18-​tetramethyl-​8-​(2-​propenyl)​


  • Catalogue No.:PA 20 01660

  • CAS :

    144432-22-4

  • Molecular Formula : C44H69NO12

  • Molecular Weight : 804.02

Drug Reference Standards & Impurity Synthesis in India
PA 20 01670

Tacrolimus Regioisomer

Tacrolimus Regioisomer


  • Catalogue No.:PA 20 01670

  • CAS :

    NA

  • Molecular Formula : C44H69NO12

  • Molecular Weight : 804.02

Drug Reference Standards & Impurity Synthesis in India
PA 20 01680

9-Norketo FK-506

9-Norketo FK-506


  • Catalogue No.:PA 20 01680

  • CAS :

    123719-19-7

  • Molecular Formula : C43H69NO11

  • Molecular Weight : 776.01

Drug Reference Standards & Impurity Synthesis in India
PA 20 01690

13-O-Desmethylated Tacrolimus

13-O-Desmethylated Tacrolimus


  • Catalogue No.:PA 20 01690

  • CAS :

    NA

  • Molecular Formula : C44H69NO12

  • Molecular Weight : 804.02

Drug Reference Standards & Impurity Synthesis in India
PA STI 013110

24,32-Bis-O-(tert-butyldimethylsilyl)-FK-506-13C, D2 (Major)

24,32-Bis-O-(tert-butyldimethylsilyl)-FK-506-13C, D2 (Major)


  • Catalogue No.:PA STI 013110

  • CAS :

    1356352-20-9

  • Molecular Formula : C5513CH95D2NO12Si2

  • Molecular Weight : 1035.54

Drug Reference Standards & Impurity Synthesis in India
PA STI 041210

FK-506-13C,D2 (Major) (Tacrolimus)

FK-506-13C,D2 (Major) (Tacrolimus)


  • Catalogue No.:PA STI 041210

  • CAS :

    1356841-89-8

  • Molecular Formula : C4313CH67D2NO12

  • Molecular Weight : 807.02

Drug Reference Standards & Impurity Synthesis in India
PA 20 01710

(S)-1-(2-((2R,3R,5S,6R)-6-((1S,3S,5E,7R,10S,11R,12S,13E)-7-Allyl-10,12-dihydroxy-14-((1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl)-1-methoxy-3,5,11,13-tetramethyl-8-oxotetradeca-5,13-dien-1-yl)-2-hydroxy-5-methoxy-3-methyltetrahydro-2H-pyran-2-yl)-2-oxoacetyl)piperidine-2-carboxylic Acid

(S)-1-(2-((2R,3R,5S,6R)-6-((1S,3S,5E,7R,10S,11R,12S,13E)-7-Allyl-10,12-dihydroxy-14-((1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl)-1-methoxy-3,5,11,13-tetramethyl-8-oxotetradeca-5,13-dien-1-yl)-2-hydroxy-5-methoxy-3-methyltetrahydro-2H-pyran-2-yl)-2-oxoacetyl)piperidine-2-carboxylic Acid


  • Catalogue No.:PA 20 01710

  • CAS :

    NA

  • Molecular Formula : C44H71NO13

  • Molecular Weight : 822.05

Drug Reference Standards & Impurity Synthesis in India
PA 20 01720

31-O-Demethyltacrolimus

31-O-Demethyltacrolimus


  • Catalogue No.:PA 20 01720

  • CAS :

    NA

  • Molecular Formula : C43H67NO12

  • Molecular Weight : 790

Drug Reference Standards & Impurity Synthesis in India
PA 20 01730

(E)-8-Ethyl-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-[(E)-2-(4-hydroxy-3-methoxycyclohexyl)-1-methylvinyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21-(4H,23H)-tetrone

(E)-8-Ethyl-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-[(E)-2-(4-hydroxy-3-methoxycyclohexyl)-1-methylvinyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21-(4H,23H)-tetrone


  • Catalogue No.:PA 20 01730

  • CAS :

    135635-46-0

  • Molecular Formula : C43H69NO12

  • Molecular Weight : 792.02

Drug Reference Standards & Impurity Synthesis in India
PA JP0221

Tacrolimus (JP 0221)

Tacrolimus (JP 0221)


  • Catalogue No.:PA JP0221

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

Drug Reference Standards & Impurity Synthesis in India
PA EPY0001926

Tacrolimus monohydrate (Y0001926)

Tacrolimus monohydrate (Y0001926)


  • Catalogue No.:PA EPY0001926

  • CAS :

    109581-93-3

  • Molecular Formula : NA

  • Molecular Weight : NA

Drug Reference Standards & Impurity Synthesis in India
PA EPY0001933

Tacrolimus for system suitability (Y0001933)

Tacrolimus for system suitability (Y0001933)


  • Catalogue No.:PA EPY0001933

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

Drug Reference Standards & Impurity Synthesis in India
PA USP1642802

Tacrolimus (1642802)

Tacrolimus (1642802)


  • Catalogue No.:PA USP1642802

  • CAS :

    109581-93-3

  • Molecular Formula : NA

  • Molecular Weight : NA

Drug Reference Standards & Impurity Synthesis in India
PA USP1642813

Tacrolimus Related Compound A (See USP Certificate for full Chemical Name) (1642813)

Tacrolimus Related Compound A (See USP Certificate for full Chemical Name) (1642813)


  • Catalogue No.:PA USP1642813

  • CAS :

    135635-46-0

  • Molecular Formula : NA

  • Molecular Weight : NA

Drug Reference Standards & Impurity Synthesis in India
PA USP1642824

Tacrolimus 8-epimer (See USP Certificate for full Chemical Name) (1642824)

Tacrolimus 8-epimer (See USP Certificate for full Chemical Name) (1642824)


  • Catalogue No.:PA USP1642824

  • CAS :

    129212-35-7

  • Molecular Formula : NA

  • Molecular Weight : NA

Drug Reference Standards & Impurity Synthesis in India
PA USP1642835

Tacrolimus 8-propyl analog (See USP Certificate for full Chemical Name) (1642835)

Tacrolimus 8-propyl analog (See USP Certificate for full Chemical Name) (1642835)


  • Catalogue No.:PA USP1642835

  • CAS :

    104987-30-6

  • Molecular Formula : NA

  • Molecular Weight : NA

Drug Reference Standards & Impurity Synthesis in India
PA USP1642857

Tacrolimus System Suitability Mixture (1642857)

Tacrolimus System Suitability Mixture (1642857)


  • Catalogue No.:PA USP1642857

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

Drug Reference Standards & Impurity Synthesis in India
PA 20 01740

24-O-Triisopropylsilyl 9-Norketo FK-506

24-O-Triisopropylsilyl 9-Norketo FK-506


  • Catalogue No.:PA 20 01740

  • CAS :

    1356930-61-4

  • Molecular Formula : C52H89NO11Si

  • Molecular Weight : 932.35

Drug Reference Standards & Impurity Synthesis in India
PA 20 01750

(3S,4R,5S,8R,12S,14S,15R,16S,18R,26aS,Z)-8-Allyl-5,15-dihydroxy-3-((E)-1-((1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl)prop-1-en-2-yl)-14,16-dimethoxy-4,10,12,18-tetramethyl-5,6,11,12,13,14,15,16,17,18,24,25,26,26a-tetradecahydro-3H-pyrido[2,1-c][1]oxa[4]azacyclotricosine-1,7,19,20,21(4H,8H,23H)-pentaone

(3S,4R,5S,8R,12S,14S,15R,16S,18R,26aS,Z)-8-Allyl-5,15-dihydroxy-3-((E)-1-((1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl)prop-1-en-2-yl)-14,16-dimethoxy-4,10,12,18-tetramethyl-5,6,11,12,13,14,15,16,17,18,24,25,26,26a-tetradecahydro-3H-pyrido[2,1-c][1]oxa[4]azacyclotricosine-1,7,19,20,21(4H,8H,23H)-pentaone


  • Catalogue No.:PA 20 01750

  • CAS :

    NA

  • Molecular Formula : C44H69NO12

  • Molecular Weight : 804.03

Drug Reference Standards & Impurity Synthesis in India
PA 20 01760

24,33-bis-O-(tert-Butyldimethylsilyl) Tacrolimus

24,33-bis-O-(tert-Butyldimethylsilyl) Tacrolimus


  • Catalogue No.:PA 20 01760

  • CAS :

    133941-75-0

  • Molecular Formula : C56H97NO12Si2

  • Molecular Weight : 1032.56

Drug Reference Standards & Impurity Synthesis in India
PA 20 01770

24,33-bis-O-(tert-Butyldimethylsilyl)-37,38-dehydro-37,38-dihydroxy-FK-506 (Mixture of Diastereomers)

24,33-bis-O-(tert-Butyldimethylsilyl)-37,38-dehydro-37,38-dihydroxy-FK-506 (Mixture of Diastereomers)


  • Catalogue No.:PA 20 01770

  • CAS :

    1356932-17-6

  • Molecular Formula : C56H99NO14Si2

  • Molecular Weight : 1066.57

Drug Reference Standards & Impurity Synthesis in India
PA 20 01780

33-tert-Butyldimethylsilyloxy-FK 506

33-tert-Butyldimethylsilyloxy-FK 506


  • Catalogue No.:PA 20 01780

  • CAS :

    104987-25-9

  • Molecular Formula : C50H83NO12Si

  • Molecular Weight : 918.29

Drug Reference Standards & Impurity Synthesis in India
PA 20 0671000

Tacrolimus System Suitability Mixture

Tacrolimus System Suitability Mixture


  • Catalogue No.:PA 20 0671000

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

Drug Reference Standards & Impurity Synthesis in India
PA STI 089131

Tacrolimus-13CD4

Tacrolimus-13CD4


  • Catalogue No.:PA STI 089131

  • CAS :

    NA

  • Molecular Formula : C4313CH65D4NO12

  • Molecular Weight : 809.05

Drug Reference Standards & Impurity Synthesis in India
PA 20 0671001

Tacrolimus Dehydro Impurity

Tacrolimus Dehydro Impurity


  • Catalogue No.:PA 20 0671001

  • CAS :

    129212-37-9

  • Molecular Formula : C44H67NO11

  • Molecular Weight : 786.02

Drug Reference Standards & Impurity Synthesis in India
PAI 20 067001

Tacrolimus Diene Impurity Mixture of 8R, 8S Isomer

Tacrolimus Diene Impurity Mixture of 8R, 8S Isomer


  • Catalogue No.:PAI 20 067001

  • CAS :

    NA

  • Molecular Formula : C44H67NO11

  • Molecular Weight : 786.02

Drug Reference Standards & Impurity Synthesis in India
PA 20 0671002

13-O-Desmethyl Tacrolimus

13-O-Desmethyl Tacrolimus


  • Catalogue No.:PA 20 0671002

  • CAS :

    139958-51-3

  • Molecular Formula : C43H67NO12

  • Molecular Weight : 790

Drug Reference Standards & Impurity Synthesis in India
PA 20 0671003

5,6,11,13,14,15,16,17,18,20,24,25,26,26a-Tetradecahydro-5,15,20-trihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-17,20-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,19,21(4H,8H,12H,23H)-tetrone

5,6,11,13,14,15,16,17,18,20,24,25,26,26a-Tetradecahydro-5,15,20-trihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-17,20-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,19,21(4H,8H,12H,23H)-tetrone


  • Catalogue No.:PA 20 0671003

  • CAS :

    152432-60-5

  • Molecular Formula : C44H69NO13

  • Molecular Weight : 820.03

Drug Reference Standards & Impurity Synthesis in India
PA 20 0671007

Tacrolimus-32-Succinate

Tacrolimus-32-Succinate


  • Catalogue No.:PA 20 0671007

  • CAS :

    NA

  • Molecular Formula : C48H73NO15

  • Molecular Weight : 904.1

Drug Reference Standards & Impurity Synthesis in India
PA 20 0671006

12-Hydroxyl Tacrolimus

12-Hydroxyl Tacrolimus


  • Catalogue No.:PA 20 0671006

  • CAS :

    NA

  • Molecular Formula : C44H69NO13

  • Molecular Weight : 820.03

Drug Reference Standards & Impurity Synthesis in India
PA 20 0671005

13, 31-O-Didesmethyl Tacrolimus

13, 31-O-Didesmethyl Tacrolimus


  • Catalogue No.:PA 20 0671005

  • CAS :

    NA

  • Molecular Formula : C42H65NO12

  • Molecular Weight : 775.98

Drug Reference Standards & Impurity Synthesis in India
PA 20 0671004

13,15-O-Didesmethyl Tacrolimus

13,15-O-Didesmethyl Tacrolimus


  • Catalogue No.:PA 20 0671004

  • CAS :

    NA

  • Molecular Formula : C42H65NO12

  • Molecular Weight : 775.98

Drug Reference Standards & Impurity Synthesis in India
PA 20 0671008

Tacrolimus 24 Succinate

Tacrolimus 24 Succinate


  • Catalogue No.:PA 20 0671008

  • CAS :

    NA

  • Molecular Formula : C48H73NO15

  • Molecular Weight : 904.1

Drug Reference Standards & Impurity Synthesis in India
PA 20 0671009

Tacrolimus C4-epimer Diene

Tacrolimus C4-epimer Diene


  • Catalogue No.:PA 20 0671009

  • CAS :

    NA

  • Molecular Formula : C44H67NO11

  • Molecular Weight : 786.02

Drug Reference Standards & Impurity Synthesis in India
PA 20 0671010

Tacrolimus Impurity 1

Tacrolimus Impurity 1


  • Catalogue No.:PA 20 0671010

  • CAS :

    NA

  • Molecular Formula : C43H69NO11

  • Molecular Weight : 776.02

Drug Reference Standards & Impurity Synthesis in India
PA 20 0671011

(3S,4R,5S,8R,12S,14S,15R,16S,18R,19R,26aS,E)-5,19-Dihydroxy-3-((E)-1-((1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl)prop-1-en-2-yl)-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-methylallyl)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-3H-15,19-epoxypyrido[2,1-c][1]oxa[4]azacyclotricosine-1,7,20,21(4H,23H)-tetraone

(3S,4R,5S,8R,12S,14S,15R,16S,18R,19R,26aS,E)-5,19-Dihydroxy-3-((E)-1-((1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl)prop-1-en-2-yl)-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-methylallyl)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-3H-15,19-epoxypyrido[2,1-c][1]oxa[4]azacyclotricosine-1,7,20,21(4H,23H)-tetraone


  • Catalogue No.:PA 20 0671011

  • CAS :

    NA

  • Molecular Formula : C45H71NO12

  • Molecular Weight : 818.06

Drug Reference Standards & Impurity Synthesis in India
PA 20 0671012

(3S,4R,5S,8R,12S,14S,15R,16S,18R,19R,25aS,E)-8-Allyl-5,19-Dihydroxy-3-((E)-1-((1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl)prop-1-en-2-yl)-14,16-dimethoxy-4,10,12,18-tetramethyl-3,4,5,6,8,11,12,13,14,15,16,17,18,19,23,24,25,25a-octadecahydro-15,18-(epoxymethano)pyrido[2,1-c][1]oxa[4]azacyclodocosine-1,7,20,26(22H)-tetraone

(3S,4R,5S,8R,12S,14S,15R,16S,18R,19R,25aS,E)-8-Allyl-5,19-Dihydroxy-3-((E)-1-((1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl)prop-1-en-2-yl)-14,16-dimethoxy-4,10,12,18-tetramethyl-3,4,5,6,8,11,12,13,14,15,16,17,18,19,23,24,25,25a-octadecahydro-15,18-(epoxymethano)pyrido[2,1-c][1]oxa[4]azacyclodocosine-1,7,20,26(22H)-tetraone


  • Catalogue No.:PA 20 0671012

  • CAS :

    1026775-21-2

  • Molecular Formula : C44H69NO12

  • Molecular Weight : 804.03

Drug Reference Standards & Impurity Synthesis in India
PA 20 0671013

Tacrolimus O-ethyl open ring (peak 1)

Tacrolimus O-ethyl open ring (peak 1)


  • Catalogue No.:PA 20 0671013

  • CAS :

    NA

  • Molecular Formula : C46H75NO13

  • Molecular Weight : 850.1

Drug Reference Standards & Impurity Synthesis in India
PA 20 0671014

Tacrolimus O-ethyl open ring (peak 2)

Tacrolimus O-ethyl open ring (peak 2)


  • Catalogue No.:PA 20 0671014

  • CAS :

    NA

  • Molecular Formula : C46H75NO13

  • Molecular Weight : 850.1

Drug Reference Standards & Impurity Synthesis in India
PA 20 0671015

Tacrolimus 20-ethoxy acetal

Tacrolimus 20-ethoxy acetal


  • Catalogue No.:PA 20 0671015

  • CAS :

    NA

  • Molecular Formula : C46H75NO13

  • Molecular Weight : 850.10

Drug Reference Standards & Impurity Synthesis in India
PA 20 0671016

15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-propyl

15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-propyl


  • Catalogue No.:PA 20 0671016

  • CAS :

    135821-69-1

  • Molecular Formula : C44H71NO12

  • Molecular Weight : 806.05

Drug Reference Standards & Impurity Synthesis in India
PA 20 0671017

(3S,4R,5S,8R,12S,14S,15R,16S,18R,19R,26aS,Z)-8-Allyl-5,19-dihydroxy-3-((E)-1-((1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl)prop-1-en-2-yl)-14,16-dimethoxy-4,10,12,18-tetramethyl-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-3H-15,19-epoxypyrido[2,1-c][1]oxa[4]azacyclotricosine-1,7,20,21(4H,23H)-tetraone

(3S,4R,5S,8R,12S,14S,15R,16S,18R,19R,26aS,Z)-8-Allyl-5,19-dihydroxy-3-((E)-1-((1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl)prop-1-en-2-yl)-14,16-dimethoxy-4,10,12,18-tetramethyl-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-3H-15,19-epoxypyrido[2,1-c][1]oxa[4]azacyclotricosine-1,7,20,21(4H,23H)-tetraone


  • Catalogue No.:PA 20 0671017

  • CAS :

    NA

  • Molecular Formula : C44H69NO12

  • Molecular Weight : 804.03

Drug Reference Standards & Impurity Synthesis in India
PA 20 0671018

(3S,4R,5S,8S,12R,14R,15S,16S,18R,25aR,Z)-8-Allyl-5,19-dihydroxy-3-((E)-1-((1R,4R)-4-hydroxy-3-methoxycyclohexyl)prop-1-en-2-yl)-14,16-dimethoxy-4,10,12,18-tetramethyl-3,4,5,6,8,11,12,13,14,15,16,17,18,19,23,24,25,25a-octadecahydro-15,18-(epoxymethano)pyrido[2,1-c][1]oxa[4]azacyclodocosine-1,7,20,26(22H)-tetraone

(3S,4R,5S,8S,12R,14R,15S,16S,18R,25aR,Z)-8-Allyl-5,19-dihydroxy-3-((E)-1-((1R,4R)-4-hydroxy-3-methoxycyclohexyl)prop-1-en-2-yl)-14,16-dimethoxy-4,10,12,18-tetramethyl-3,4,5,6,8,11,12,13,14,15,16,17,18,19,23,24,25,25a-octadecahydro-15,18-(epoxymethano)pyrido[2,1-c][1]oxa[4]azacyclodocosine-1,7,20,26(22H)-tetraone


  • Catalogue No.:PA 20 0671018

  • CAS :

    NA

  • Molecular Formula : C44H69NO12

  • Molecular Weight : 804.03

Drug Reference Standards & Impurity Synthesis in India
PA 20 0671019

(3S,6R,10S,12S,13R,14S,16R,17R,24aS,E)-6-Allyl-17-hydroxy-3-((2S,3S,E)-3-hydroxy-5-((1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl)-4-methylpent-4-en-2-yl)-12,14-dimethoxy-8,10,16-trimethyl-6,9,10,11,12,13,14,15,16,17,22,23,24,24a-tetradecahydro-3H-13,17-epoxypyrido[2,1-c][1]oxa[4]azacyclohenicosine-1,5,18,19(4H,21H)-tetraone

(3S,6R,10S,12S,13R,14S,16R,17R,24aS,E)-6-Allyl-17-hydroxy-3-((2S,3S,E)-3-hydroxy-5-((1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl)-4-methylpent-4-en-2-yl)-12,14-dimethoxy-8,10,16-trimethyl-6,9,10,11,12,13,14,15,16,17,22,23,24,24a-tetradecahydro-3H-13,17-epoxypyrido[2,1-c][1]oxa[4]azacyclohenicosine-1,5,18,19(4H,21H)-tetraone


  • Catalogue No.:PA 20 0671019

  • CAS :

    NA

  • Molecular Formula : C44H69NO12

  • Molecular Weight : 804.03

Drug Reference Standards & Impurity Synthesis in India
PA 20 0671020

(3S,4E,6S,7S,10R,11E,14S,16S,17R,18S,20R,21R,28aS)-10-Allyl-7,21-dihydroxy-3-((1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl)-16,18-dimethoxy-4,6,12,14,20-pentamethyl-7,8,10,13,14,15,16,17,18,19,20,21,26,27,28,28a-hexadecahydro-3H-17,21-epoxypyrido[2,1-c][1]oxa[4]azacyclopentacosine-1,9,22,23(6H,25H)-tetraone

(3S,4E,6S,7S,10R,11E,14S,16S,17R,18S,20R,21R,28aS)-10-Allyl-7,21-dihydroxy-3-((1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl)-16,18-dimethoxy-4,6,12,14,20-pentamethyl-7,8,10,13,14,15,16,17,18,19,20,21,26,27,28,28a-hexadecahydro-3H-17,21-epoxypyrido[2,1-c][1]oxa[4]azacyclopentacosine-1,9,22,23(6H,25H)-tetraone


  • Catalogue No.:PA 20 0671020

  • CAS :

    NA

  • Molecular Formula : C44H69NO12

  • Molecular Weight : 804.03

Drug Reference Standards & Impurity Synthesis in India
PA 20 0671021

11,15-Epoxy-4,6-(epoxymethano)-2H,7H-pyrano[3,2-r]pyrido[2,1-c][1,4]oxaazacyclotricosine-16,17,23(19H)-trione, 25-[(1E)-2-[(1R,3R,4R)-3,4-dihydroxycyclohexyl]-1-methylethenyl]-3,4,4a,8,9,10,11,12,13,14,15,20,21,22,22a,25,26,27,28,28a-eicosahydro-15,27,28a-trihydroxy-10,12-dimethoxy-8,14,26-trimethyl-, (8S,10S,11R,12S,14R,15R,22aS,25S,26R,27S)

11,15-Epoxy-4,6-(epoxymethano)-2H,7H-pyrano[3,2-r]pyrido[2,1-c][1,4]oxaazacyclotricosine-16,17,23(19H)-trione, 25-[(1E)-2-[(1R,3R,4R)-3,4-dihydroxycyclohexyl]-1-methylethenyl]-3,4,4a,8,9,10,11,12,13,14,15,20,21,22,22a,25,26,27,28,28a-eicosahydro-15,27,28a-trihydroxy-10,12-dimethoxy-8,14,26-trimethyl-, (8S,10S,11R,12S,14R,15R,22aS,25S,26R,27S)


  • Catalogue No.:PA 20 0671021

  • CAS :

    160892-64-8

  • Molecular Formula : C43H67NO14

  • Molecular Weight : 822.00

Drug Reference Standards & Impurity Synthesis in India
PA 20 0671022

(3S,4R,5S,8R,12S,14S,15R,16S,18R,19S,26aS,E)-8-Allyl-20-ethoxy-5,19,20-trihydroxy-3-((E)-1-((1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl)prop-1-en-2-yl)-14,16-dimethoxy-4,10,12,18-tetramethyl-3,4,5,6,11,12,13,14,15,16,17,18,19,20,24,25,26,26a-octadecahydro-7H-15,19-epoxypyrido[2,1-c][1]oxa[4]azacyclotricosine-1,7,21(8H,23H)-trione

(3S,4R,5S,8R,12S,14S,15R,16S,18R,19S,26aS,E)-8-Allyl-20-ethoxy-5,19,20-trihydroxy-3-((E)-1-((1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl)prop-1-en-2-yl)-14,16-dimethoxy-4,10,12,18-tetramethyl-3,4,5,6,11,12,13,14,15,16,17,18,19,20,24,25,26,26a-octadecahydro-7H-15,19-epoxypyrido[2,1-c][1]oxa[4]azacyclotricosine-1,7,21(8H,23H)-trione


  • Catalogue No.:PA 20 0671022

  • CAS :

    NA

  • Molecular Formula : C46H75NO13

  • Molecular Weight : 850.1

Drug Reference Standards & Impurity Synthesis in India
PA 20 0671023

(3S,4R,5S,8R,12S,14S,15R,16S,18R,20R,26aS,E)-8-Allyl-20-ethoxy-5,15,20-trihydroxy-3-((E)-1-((1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl)prop-1-en-2-yl)-14,16-dimethoxy-4,10,12,18-tetramethyl-3,4,5,6,11,12,13,14,15,16,17,18,24,25,26,26a-hexadecahydro-7H-pyrido[2,1-c][1]oxa[4]azacyclotricosine-1,7,19,21(8H,20H,23H)-tetraone

(3S,4R,5S,8R,12S,14S,15R,16S,18R,20R,26aS,E)-8-Allyl-20-ethoxy-5,15,20-trihydroxy-3-((E)-1-((1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl)prop-1-en-2-yl)-14,16-dimethoxy-4,10,12,18-tetramethyl-3,4,5,6,11,12,13,14,15,16,17,18,24,25,26,26a-hexadecahydro-7H-pyrido[2,1-c][1]oxa[4]azacyclotricosine-1,7,19,21(8H,20H,23H)-tetraone


  • Catalogue No.:PA 20 0671023

  • CAS :

    NA

  • Molecular Formula : C46H75NO13

  • Molecular Weight : 850.1

Drug Reference Standards & Impurity Synthesis in India
PA 20 0671024

(3S,4R,5S,8R,12S,14S,15R,16S,18R,19R,26aS,E)-8-Allyl-5,19-Dihydroxy-3-((E)-1-((1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl)prop-1-en-2-yl)-14,16-dimethoxy-4,10,12,18-tetramethyl-3,4,5,6,11,12,13,14,15,16,17,18,19,20,24,25,26,26a-octadecahydro-7H-15,19:20,23-diepoxypyrido[2,1-c][1]oxa[4]azacyclotricosine-1,7,21(8H,23H)-trione

(3S,4R,5S,8R,12S,14S,15R,16S,18R,19R,26aS,E)-8-Allyl-5,19-Dihydroxy-3-((E)-1-((1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl)prop-1-en-2-yl)-14,16-dimethoxy-4,10,12,18-tetramethyl-3,4,5,6,11,12,13,14,15,16,17,18,19,20,24,25,26,26a-octadecahydro-7H-15,19:20,23-diepoxypyrido[2,1-c][1]oxa[4]azacyclotricosine-1,7,21(8H,23H)-trione


  • Catalogue No.:PA 20 0671024

  • CAS :

    NA

  • Molecular Formula : C44H69NO12

  • Molecular Weight : 804.03

Drug Reference Standards & Impurity Synthesis in India
PA 20 0671025

(3R,4E,6S,7S,10R,11E,14S,16S,17R,18S,20R,21R,28aR)-10-Allyl-7,21-Dihydroxy-3-((1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl)-16,18-dimethoxy-4,6,12,14,20-pentamethyl-7,8,10,13,14,15,16,17,18,19,20,21,26,27,28,28a-hexadecahydro-3H-17,21-epoxypyrido[2,1-c][1]oxa[4]azacyclopentacosine-1,9,22,23(6H,25H)-tetraone

(3R,4E,6S,7S,10R,11E,14S,16S,17R,18S,20R,21R,28aR)-10-Allyl-7,21-Dihydroxy-3-((1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl)-16,18-dimethoxy-4,6,12,14,20-pentamethyl-7,8,10,13,14,15,16,17,18,19,20,21,26,27,28,28a-hexadecahydro-3H-17,21-epoxypyrido[2,1-c][1]oxa[4]azacyclopentacosine-1,9,22,23(6H,25H)-tetraone


  • Catalogue No.:PA 20 0671025

  • CAS :

    NA

  • Molecular Formula : C44H69NO12

  • Molecular Weight : 804.03

Drug Reference Standards & Impurity Synthesis in India
PA 20 0671026

(3R,4E,6S,7R,10R,11E,14S,16S,17R,18S,20R,21R,28aS)-10-Allyl-7,21-dihydroxy-3-((1S,3S,4S)-4-hydroxy-3-methoxycyclohexyl)-16,18-dimethoxy-4,6,12,14,20-pentamethyl-7,8,10,13,14,15,16,17,18,19,20,21,26,27,28,28a-hexadecahydro-3H-17,21-epoxypyrido[2,1-c][1]oxa[4]azacyclopentacosine-1,9,22,23(6H,25H)-tetraone

(3R,4E,6S,7R,10R,11E,14S,16S,17R,18S,20R,21R,28aS)-10-Allyl-7,21-dihydroxy-3-((1S,3S,4S)-4-hydroxy-3-methoxycyclohexyl)-16,18-dimethoxy-4,6,12,14,20-pentamethyl-7,8,10,13,14,15,16,17,18,19,20,21,26,27,28,28a-hexadecahydro-3H-17,21-epoxypyrido[2,1-c][1]oxa[4]azacyclopentacosine-1,9,22,23(6H,25H)-tetraone


  • Catalogue No.:PA 20 0671026

  • CAS :

    NA

  • Molecular Formula : C44H69NO12

  • Molecular Weight : 804.03

Drug Reference Standards & Impurity Synthesis in India
PA 20 0671027

Dihydroxy Tacrolimus

Dihydroxy Tacrolimus


  • Catalogue No.:PA 20 0671027

  • CAS :

    1224629-33-7

  • Molecular Formula : C44H71NO14

  • Molecular Weight : 838.05

Drug Reference Standards & Impurity Synthesis in India
PA 20 0671028

(1E,3S,4R,5R,8R,9E,12S,14S)-8-allyl-5-hydroxy-1-((1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl)-14-methoxy-14-((2R,3S,5R)-3-methoxy-5-methyl-6-oxotetrahydro-2H-pyran-2-yl)-2,4,10,12-tetramethyl-7-oxotetradeca-1,9-dien-3-yl (S)-1-formylpiperidine-2-carboxylate

(1E,3S,4R,5R,8R,9E,12S,14S)-8-allyl-5-hydroxy-1-((1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl)-14-methoxy-14-((2R,3S,5R)-3-methoxy-5-methyl-6-oxotetrahydro-2H-pyran-2-yl)-2,4,10,12-tetramethyl-7-oxotetradeca-1,9-dien-3-yl (S)-1-formylpiperidine-2-carboxylate


  • Catalogue No.:PA 20 0671028

  • CAS :

    NA

  • Molecular Formula : C43H69NO11

  • Molecular Weight : 776.02

Drug Reference Standards & Impurity Synthesis in India
PA 20 0671029

Tacrolimus 21-Carboxylic Acid Nitroso Impurity

Tacrolimus 21-Carboxylic Acid Nitroso Impurity


  • Catalogue No.:PA 20 0671029

  • CAS :

    NA

  • Molecular Formula : C44H70N2O14

  • Molecular Weight : 851.04

Drug Reference Standards & Impurity Synthesis in India
PA 20 0671030

8-Allyl-3-(1-(3,4-dihydroxycyclohexyl)prop-1-en-2-yl)-5,19-dihydroxy-14,16-dimethoxy-4,10,12,18-tetramethyl-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-3H-15,19-epoxypyrido[2,1-c][1]oxa[4]azacyclotricosine-1,7,20,21(4H,23H)-tetraone

8-Allyl-3-(1-(3,4-dihydroxycyclohexyl)prop-1-en-2-yl)-5,19-dihydroxy-14,16-dimethoxy-4,10,12,18-tetramethyl-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-3H-15,19-epoxypyrido[2,1-c][1]oxa[4]azacyclotricosine-1,7,20,21(4H,23H)-tetraone


  • Catalogue No.:PA 20 0671030

  • CAS :

    135635-47-1

  • Molecular Formula : C43H67NO12

  • Molecular Weight : 790

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