Saxagliptin-impurities | Pharmaffiliates

saxagliptin

Saxagliptin is used as monotherapy or in combination with other drugs for the treatment of type 2 diabetes. It is an oral hypoglycemic SaxagliptinIt, it is sold under the brand name Onglyza.Reference standards of Saxagliptin API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

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    [pname] => Saxagliptin - API Standards 
    [catalogue_number] => PA 19 40000
    [category_ids] => ,79,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 315.41
    [form] => C18H25N3O2
    [cas] => 361442-04-8
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PA 19 40000

Saxagliptin - API Standards


  • Catalogue No.:PA 19 40000

  • CAS :

    361442-04-8

  • Molecular Formula : C18H25N3O2

  • Molecular Weight : 315.41

stdClass Object
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    [pname] => Saxagliptin Monohydrate - API Standards 
    [catalogue_number] => PA 19 40510
    [category_ids] => ,79,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 333.43
    [form] => C18H27N3O3
    [cas] => 945667-22-1
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PA 19 40510

Saxagliptin Monohydrate - API Standards


  • Catalogue No.:PA 19 40510

  • CAS :

    945667-22-1

  • Molecular Formula : C18H27N3O3

  • Molecular Weight : 333.43

stdClass Object
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    [pname] => (2S,2R',trans)-Saxagliptin
    [catalogue_number] => PA 19 40520
    [category_ids] => ,79,69,71,75,78,70,82,
    [chemical_name] => 
    [weight] => 315.41
    [form] => C18H25N3O2
    [cas] => 1564265-98-0
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PA 19 40520

(2S,2R',trans)-Saxagliptin


  • Catalogue No.:PA 19 40520

  • CAS :

    1564265-98-0

  • Molecular Formula : C18H25N3O2

  • Molecular Weight : 315.41

stdClass Object
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    [catalogue_number] => PA 19 40530
    [category_ids] => ,79,69,71,75,78,70,82,
    [chemical_name] => 
    [weight] => 315.41
    [form] => C18H25N3O2
    [cas] => 1564266-00-7
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PA 19 40530

(2'S,2R,trans)-Saxagliptin


  • Catalogue No.:PA 19 40530

  • CAS :

    1564266-00-7

  • Molecular Formula : C18H25N3O2

  • Molecular Weight : 315.41

stdClass Object
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    [pname] => (2S,2S',trans)-Saxagliptin
    [catalogue_number] => PA 19 40540
    [category_ids] => ,79,69,71,75,78,70,82,
    [chemical_name] => 
    [weight] => 315.41
    [form] => C18H25N3O2
    [cas] => 1564265-96-8
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PA 19 40540

(2S,2S',trans)-Saxagliptin


  • Catalogue No.:PA 19 40540

  • CAS :

    1564265-96-8

  • Molecular Formula : C18H25N3O2

  • Molecular Weight : 315.41

stdClass Object
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    [pname] => N-Formyl Saxagliptin
    [catalogue_number] => PA 19 40550
    [category_ids] => ,79,69,71,75,78,70,82,
    [chemical_name] => 
    [weight] => 343.42
    [form] => C19H25N3O3
    [cas] => NA
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PA 19 40550

N-Formyl Saxagliptin


  • Catalogue No.:PA 19 40550

  • CAS :

    NA

  • Molecular Formula : C19H25N3O3

  • Molecular Weight : 343.42

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    [pname] => 5-Hydroxy Saxagliptin
    [catalogue_number] => PA 19 40560
    [category_ids] => ,79,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 331.41
    [form] => C18H25N3O3
    [cas] => 841302-24-7
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PA 19 40560

5-Hydroxy Saxagliptin


  • Catalogue No.:PA 19 40560

  • CAS :

    841302-24-7

  • Molecular Formula : C18H25N3O3

  • Molecular Weight : 331.41

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    [pname] => 3-Deshydroxy 3-Keto Saxagliptin
    [catalogue_number] => PA 19 40570
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    [chemical_name] => 
    [weight] => 313.39
    [form] => C18H23N3O2
    [cas] => 2173146-34-2
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PA 19 40570

3-Deshydroxy 3-Keto Saxagliptin


  • Catalogue No.:PA 19 40570

  • CAS :

    2173146-34-2

  • Molecular Formula : C18H23N3O2

  • Molecular Weight : 313.39

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    [catalogue_number] => PA 19 40590
    [category_ids] => ,79,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 226.27
    [form] => C11H18N2O3
    [cas] => 361440-67-7
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PA 19 40590

N-Boc-L-cis-4,5-Methanoprolineamide


  • Catalogue No.:PA 19 40590

  • CAS :

    361440-67-7

  • Molecular Formula : C11H18N2O3

  • Molecular Weight : 226.27

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    [pname] => Saxagliptin Keto Impurity
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    [form] => C18H23N3O2
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PA 19 40610

Saxagliptin Keto Impurity


  • Catalogue No.:PA 19 40610

  • CAS :

    NA

  • Molecular Formula : C18H23N3O2

  • Molecular Weight : 313.39

stdClass Object
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    [pname] => Saxagliptin Monohydrate - Impurity A
    [catalogue_number] => PA 19 40630
    [category_ids] => 82,79,78,75,71,70,69
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    [weight] => 315.41
    [form] => C18H25N3O2
    [cas] => 1350800-76-8
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PA 19 40630

Saxagliptin Monohydrate - Impurity A


  • Catalogue No.:PA 19 40630

  • CAS :

    1350800-76-8

  • Molecular Formula : C18H25N3O2

  • Molecular Weight : 315.41

stdClass Object
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    [pname] => (2'R,2S,cis)-Saxagliptin
    [catalogue_number] => PA 19 40650
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    [weight] => 315.41
    [form] => C18H25N3O2
    [cas] => 1564265-93-5
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PA 19 40650

(2'R,2S,cis)-Saxagliptin


  • Catalogue No.:PA 19 40650

  • CAS :

    1564265-93-5

  • Molecular Formula : C18H25N3O2

  • Molecular Weight : 315.41

stdClass Object
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    [pname] => (1S,3S,5S)-2-Azabicyclo[3.1.0]hexane-3-carboxamide Methanesulfonate
    [catalogue_number] => PA 19 40660
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    [chemical_name] => 
    [weight] => 222.26
    [form] => C7H14N2O4S
    [cas] => 709031-45-8
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PA 19 40660

(1S,3S,5S)-2-Azabicyclo[3.1.0]hexane-3-carboxamide Methanesulfonate


  • Catalogue No.:PA 19 40660

  • CAS :

    709031-45-8

  • Molecular Formula : C7H14N2O4S

  • Molecular Weight : 222.26

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    [weight] => 325.4
    [form] => C17H27NO5
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PA 19 40670

(2S)-2-((tert-Butoxycarbonyl)amino)-2-((1s,3R,5S,7R)-4-hydroxyadamantan-1-yl)acetic Acid


  • Catalogue No.:PA 19 40670

  • CAS :

    NA

  • Molecular Formula : C17H27NO5

  • Molecular Weight : 325.4

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    [catalogue_number] => PA 19 40680
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    [weight] => 325.4
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PA 19 40680

Boc-3-Hydroxy-1-adamantyl-L-glycine


  • Catalogue No.:PA 19 40680

  • CAS :

    1334321-39-9

  • Molecular Formula : C17H27NO5

  • Molecular Weight : 325.4

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PA 19 40690

(1S,3R,5S)-2-Azabicyclo[3.1.0]hexane-3-carboxamide methanesulfonate


  • Catalogue No.:PA 19 40690

  • CAS :

    1564266-74-5

  • Molecular Formula : C7H14N2O4S

  • Molecular Weight : 222.26

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    [catalogue_number] => PA 19 40700
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PA 19 40700

(1R,3S,5R)-2-Azabicyclo[3.1.0]hexane-3-carboxamide methanesulfonate


  • Catalogue No.:PA 19 40700

  • CAS :

    1564266-70-1

  • Molecular Formula : C7H14N2O4S

  • Molecular Weight : 222.26

stdClass Object
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    [catalogue_number] => PA 19 40770
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    [weight] => 315.41
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PA 19 40770

(2'R,2R,trans)-Saxagliptin


  • Catalogue No.:PA 19 40770

  • CAS :

    1564266-03-0

  • Molecular Formula : C18H25N3O2

  • Molecular Weight : 315.41

stdClass Object
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    [pname] => (R)-2-((S)-2-((1S,3S,5S)-3-Cyano-2-azabicyclo[3.1.0]hexan-2-yl)-1-((1r,3R,5R,7S)-3-hydroxyadamantan-1-yl)-2-oxoethyl)succinic Acid
    [catalogue_number] => PA 19 40780
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    [weight] => 416.47
    [form] => C22H28N2O6
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PA 19 40780

(R)-2-((S)-2-((1S,3S,5S)-3-Cyano-2-azabicyclo[3.1.0]hexan-2-yl)-1-((1r,3R,5R,7S)-3-hydroxyadamantan-1-yl)-2-oxoethyl)succinic Acid


  • Catalogue No.:PA 19 40780

  • CAS :

    NA

  • Molecular Formula : C22H28N2O6

  • Molecular Weight : 416.47

stdClass Object
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    [catalogue_number] => PA 19 40790
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    [weight] => 433.55
    [form] => C23H35N3O5
    [cas] => 361442-01-5
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PA 19 40790

(S)-N-Boc-3-hydroxyadamantylglycine-L-cis-4,5-methanoprolinamide


  • Catalogue No.:PA 19 40790

  • CAS :

    361442-01-5

  • Molecular Formula : C23H35N3O5

  • Molecular Weight : 433.55

stdClass Object
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    [weight] => 415.53
    [form] => C23H33N3O4
    [cas] => 709031-43-6
    [pslug] => 709031-43-6-boc-saxagliptin-pa1940800
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PA 19 40800

Boc-Saxagliptin


  • Catalogue No.:PA 19 40800

  • CAS :

    709031-43-6

  • Molecular Formula : C23H33N3O4

  • Molecular Weight : 415.53

stdClass Object
(
    [pname] => Saxagliptin Monohydrate - Impurity B
    [catalogue_number] => PA 19 40810
    [category_ids] => 82,79,78,75,70
    [chemical_name] => 
    [weight] => 333.43
    [form] => C18H27N3O3
    [cas] => 1496712-39-0
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PA 19 40810

Saxagliptin Monohydrate - Impurity B


  • Catalogue No.:PA 19 40810

  • CAS :

    1496712-39-0

  • Molecular Formula : C18H27N3O3

  • Molecular Weight : 333.43

stdClass Object
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    [pname] => Hydroxy Saxagliptin-13C3
    [catalogue_number] => PA STI 051620
    [category_ids] => ,79,69,71,98,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 334.39
    [form] => C1513C3H25N3O3
    [cas] => 1346597-23-6
    [pslug] => 1346597-23-6-hydroxy-saxagliptin-13c3-pasti051620
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PA STI 051620

Hydroxy Saxagliptin-13C3


  • Catalogue No.:PA STI 051620

  • CAS :

    1346597-23-6

  • Molecular Formula : C1513C3H25N3O3

  • Molecular Weight : 334.39

stdClass Object
(
    [pname] => Saxagliptin-13C3
    [catalogue_number] => PA STI 078820
    [category_ids] => ,79,69,71,98,78,70,82,
    [chemical_name] => 
    [weight] => 318.39
    [form] => C1513C3H25N3O2
    [cas] => 1246812-44-1
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PA STI 078820

Saxagliptin-13C3


  • Catalogue No.:PA STI 078820

  • CAS :

    1246812-44-1

  • Molecular Formula : C1513C3H25N3O2

  • Molecular Weight : 318.39

stdClass Object
(
    [pname] => (2’S,2R,cis)-Saxagliptin
    [catalogue_number] => PA 19 40850
    [category_ids] => 82,79,78,75,71,70,69
    [chemical_name] => 
    [weight] => 315.42
    [form] => C18H25N3O2
    [cas] => 1564265-94-6
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PA 19 40850

(2’S,2R,cis)-Saxagliptin


  • Catalogue No.:PA 19 40850

  • CAS :

    1564265-94-6

  • Molecular Formula : C18H25N3O2

  • Molecular Weight : 315.42

stdClass Object
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    [pname] => (S)-2-((tert-Butoxycarbonyl)amino)-2-((1s,3R,5S,7R)-4-oxoadamantan-1-yl)acetic Acid
    [catalogue_number] => PA 19 40860
    [category_ids] => ,79,69,71,75,78,70,82,
    [chemical_name] => 
    [weight] => 323.39
    [form] => C17H25NO5
    [cas] => 2173146-31-9
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PA 19 40860

(S)-2-((tert-Butoxycarbonyl)amino)-2-((1s,3R,5S,7R)-4-oxoadamantan-1-yl)acetic Acid


  • Catalogue No.:PA 19 40860

  • CAS :

    2173146-31-9

  • Molecular Formula : C17H25NO5

  • Molecular Weight : 323.39

stdClass Object
(
    [pname] => (S)-Boc-adamantylglycine
    [catalogue_number] => PA 19 40900
    [category_ids] => 84,79,69
    [chemical_name] => 
    [weight] => 309.4
    [form] => C17H27NO4
    [cas] => 361441-97-6
    [pslug] => 361441-97-6-s-boc-adamantylglycine-pa1940900
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PA 19 40900

(S)-Boc-adamantylglycine


  • Catalogue No.:PA 19 40900

  • CAS :

    361441-97-6

  • Molecular Formula : C17H27NO4

  • Molecular Weight : 309.4

stdClass Object
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    [pname] => (S)-Adamantylglycine Hydrochloride
    [catalogue_number] => PA 19 40910
    [category_ids] => 84,79,69
    [chemical_name] => 
    [weight] => 245.75
    [form] => C12H20ClNO2
    [cas] => 102502-64-7
    [pslug] => 102502-64-7-s-adamantylglycine-hydrochloride-pa1940910
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PA 19 40910

(S)-Adamantylglycine Hydrochloride


  • Catalogue No.:PA 19 40910

  • CAS :

    102502-64-7

  • Molecular Formula : C12H20ClNO2

  • Molecular Weight : 245.75

stdClass Object
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    [pname] => tert-Butyl (1R,3R,5R)-3-carbamoyl-2-azabicyclo[3.1.0]hexane-2-carboxylate
    [catalogue_number] => PA 19 40930
    [category_ids] => ,79,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 226.28
    [form] => C11H18N2O3
    [cas] => 1564266-54-1
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PA 19 40930

tert-Butyl (1R,3R,5R)-3-carbamoyl-2-azabicyclo[3.1.0]hexane-2-carboxylate


  • Catalogue No.:PA 19 40930

  • CAS :

    1564266-54-1

  • Molecular Formula : C11H18N2O3

  • Molecular Weight : 226.28

stdClass Object
(
    [pname] => tert-Butyl (1S,3R,5S)-3-carbamoyl-2-azabicyclo[3.1.0]hexane-2-carboxylate
    [catalogue_number] => PA 19 40940
    [category_ids] => ,79,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 226.28
    [form] => C11H18N2O3
    [cas] => 1564266-79-0
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PA 19 40940

tert-Butyl (1S,3R,5S)-3-carbamoyl-2-azabicyclo[3.1.0]hexane-2-carboxylate


  • Catalogue No.:PA 19 40940

  • CAS :

    1564266-79-0

  • Molecular Formula : C11H18N2O3

  • Molecular Weight : 226.28

stdClass Object
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    [pname] => tert-Butyl (1R,3S,5R)-3-carbamoyl-2-azabicyclo[3.1.0]hexane-2-carboxylate
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    [weight] => 226.28
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PA 19 40950

tert-Butyl (1R,3S,5R)-3-carbamoyl-2-azabicyclo[3.1.0]hexane-2-carboxylate


  • Catalogue No.:PA 19 40950

  • CAS :

    1445592-86-8

  • Molecular Formula : C11H18N2O3

  • Molecular Weight : 226.28

stdClass Object
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    [pname] => (1aS,4S,7aS)-4-((1r,3R,5R,7S)-3-Hydroxyadamantan-1-yl)-6-imino-5-nitrosooctahydro-3H-cyclopropa[4,5]pyrrolo[1,2-a]pyrazin-3-one
    [catalogue_number] => PA 19 0401029
    [category_ids] => ,69,70,71,78,79,82,162,
    [chemical_name] => 
    [weight] => 344.42
    [form] => C18H24N4O3
    [cas] => NA
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PA 19 0401029

(1aS,4S,7aS)-4-((1r,3R,5R,7S)-3-Hydroxyadamantan-1-yl)-6-imino-5-nitrosooctahydro-3H-cyclopropa[4,5]pyrrolo[1,2-a]pyrazin-3-one


  • Catalogue No.:PA 19 0401029

  • CAS :

    NA

  • Molecular Formula : C18H24N4O3

  • Molecular Weight : 344.42

stdClass Object
(
    [pname] => N-((S)-((3S,5S,7S)-Adamantan-1-yl)(cyano)methyl)-N-((R)-2-hydroxy-1-phenylethyl)nitrous Amide
    [catalogue_number] => PA 19 0401030
    [category_ids] => ,79,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 339.44
    [form] => C20H25N3O2
    [cas] => NA
    [pslug] => n-s-3s-5s-7s-adamantan-1-yl-cyano-methyl-n-r-2-hydroxy-1-phenylethyl-nitrous-amide-pa190401030
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PA 19 0401030

N-((S)-((3S,5S,7S)-Adamantan-1-yl)(cyano)methyl)-N-((R)-2-hydroxy-1-phenylethyl)nitrous Amide


  • Catalogue No.:PA 19 0401030

  • CAS :

    NA

  • Molecular Formula : C20H25N3O2

  • Molecular Weight : 339.44

stdClass Object
(
    [pname] => (S)-2-(Adamantan-1-yl)-2-(((R)-2-hydroxy-1-phenylethyl)amino)acetic Acid
    [catalogue_number] => PA 19 0401032
    [category_ids] => ,79,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 329.44
    [form] => C20H27NO3
    [cas] => 769912-51-8
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PA 19 0401032

(S)-2-(Adamantan-1-yl)-2-(((R)-2-hydroxy-1-phenylethyl)amino)acetic Acid


  • Catalogue No.:PA 19 0401032

  • CAS :

    769912-51-8

  • Molecular Formula : C20H27NO3

  • Molecular Weight : 329.44