Sitagliptin-impurities | Pharmaffiliates

sitagliptin

Sitagliptin impurity B is also known as Defluoro Sitagliptin, an impurity of Sitagliptan, an dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Reference standards of Sitagliptin API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
(
    [pname] => (R)-3-Amino-4-(2-fluorophenyl)-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)butan-1-one
    [catalogue_number] => PA 19 0481062
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 371.34
    [form] => C16H17F4N5O
    [cas] => 945261-45-0
    [pslug] => 945261-45-0-r-3-amino-4-2-fluorophenyl-1-3-trifluoromethyl-5-6-dihydro-1-2-4-triazolo-4-3-a-pyrazin-7-8h-yl-butan-1-one-pa190481062
    [latest_product] => 0
    [linkproducts] => 0
    [offers_id] => 
    [offers_name] => 
    [offers_status] => 
    [offers_start_date] => 
    [offers_end_date] => 
    [pageview] => 
    [offers_slug] => 
    [offers_product_id] => 
    [offers_product_code] => 
    [offers_master_id] => 
    [offer_percentage] => 
    [offers_product_main_cat] => 
)
PA 19 0481062

(R)-3-Amino-4-(2-fluorophenyl)-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)butan-1-one


  • Catalogue No.:PA 19 0481062

  • CAS :

    945261-45-0

  • Molecular Formula : C16H17F4N5O

  • Molecular Weight : 371.34

stdClass Object
(
    [pname] => (R)-3-Amino-4-(2-chlorophenyl)-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)butan-1-one
    [catalogue_number] => PA 19 0481063
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 387.79
    [form] => C16H17ClF3N5O
    [cas] => 945261-56-3
    [pslug] => 945261-56-3-r-3-amino-4-2-chlorophenyl-1-3-trifluoromethyl-5-6-dihydro-1-2-4-triazolo-4-3-a-pyrazin-7-8h-yl-butan-1-one-pa190481063
    [latest_product] => 0
    [linkproducts] => 0
    [offers_id] => 
    [offers_name] => 
    [offers_status] => 
    [offers_start_date] => 
    [offers_end_date] => 
    [pageview] => 
    [offers_slug] => 
    [offers_product_id] => 
    [offers_product_code] => 
    [offers_master_id] => 
    [offer_percentage] => 
    [offers_product_main_cat] => 
)
PA 19 0481063

(R)-3-Amino-4-(2-chlorophenyl)-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)butan-1-one


  • Catalogue No.:PA 19 0481063

  • CAS :

    945261-56-3

  • Molecular Formula : C16H17ClF3N5O

  • Molecular Weight : 387.79

stdClass Object
(
    [pname] => (R)-3-Amino-4-(2,4-dichlorophenyl)-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)butan-1-one
    [catalogue_number] => PA 19 0481064
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 422.23
    [form] => C16H16Cl2F3N5O
    [cas] => 945261-60-9
    [pslug] => 945261-60-9-r-3-amino-4-2-4-dichlorophenyl-1-3-trifluoromethyl-5-6-dihydro-1-2-4-triazolo-4-3-a-pyrazin-7-8h-yl-butan-1-one-pa190481064
    [latest_product] => 0
    [linkproducts] => 0
    [offers_id] => 
    [offers_name] => 
    [offers_status] => 
    [offers_start_date] => 
    [offers_end_date] => 
    [pageview] => 
    [offers_slug] => 
    [offers_product_id] => 
    [offers_product_code] => 
    [offers_master_id] => 
    [offer_percentage] => 
    [offers_product_main_cat] => 
)
PA 19 0481064

(R)-3-Amino-4-(2,4-dichlorophenyl)-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)butan-1-one


  • Catalogue No.:PA 19 0481064

  • CAS :

    945261-60-9

  • Molecular Formula : C16H16Cl2F3N5O

  • Molecular Weight : 422.23

stdClass Object
(
    [pname] => 3-Nitroso-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one
    [catalogue_number] => PA 19 0481072
    [category_ids] => ,69,70,78,82,162,
    [chemical_name] => 
    [weight] => 421.3
    [form] => C16H13F6N5O2
    [cas] => NA
    [pslug] => 3-nitroso-1-3-trifluoromethyl-5-6-dihydro-1-2-4-triazolo-4-3-a-pyrazin-7-8h-yl-4-2-4-5-trifluorophenyl-butan-1-one-pa190481072
    [latest_product] => 0
    [linkproducts] => 0
    [offers_id] => 
    [offers_name] => 
    [offers_status] => 
    [offers_start_date] => 
    [offers_end_date] => 
    [pageview] => 
    [offers_slug] => 
    [offers_product_id] => 
    [offers_product_code] => 
    [offers_master_id] => 
    [offer_percentage] => 
    [offers_product_main_cat] => 
)
PA 19 0481072

3-Nitroso-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one


  • Catalogue No.:PA 19 0481072

  • CAS :

    NA

  • Molecular Formula : C16H13F6N5O2

  • Molecular Weight : 421.3

stdClass Object
(
    [pname] => (R)-3-Amino-4-(2,4,5-trifluorophenyl)butanamide
    [catalogue_number] => PA 19 0481073
    [category_ids] => ,75,78,70,82,
    [chemical_name] => 
    [weight] => 232.21
    [form] => C10H11F3N2O
    [cas] => 2137101-64-3
    [pslug] => 2137101-64-3-r-3-amino-4-2-4-5-trifluorophenyl-butanamide-pa190481073
    [latest_product] => 0
    [linkproducts] => 0
    [offers_id] => 
    [offers_name] => 
    [offers_status] => 
    [offers_start_date] => 
    [offers_end_date] => 
    [pageview] => 
    [offers_slug] => 
    [offers_product_id] => 
    [offers_product_code] => 
    [offers_master_id] => 
    [offer_percentage] => 
    [offers_product_main_cat] => 
)
PA 19 0481073

(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanamide


  • Catalogue No.:PA 19 0481073

  • CAS :

    2137101-64-3

  • Molecular Formula : C10H11F3N2O

  • Molecular Weight : 232.21

stdClass Object
(
    [pname] => Isopropyl (R)-3-amino-4-(2,4,5-trifluorophenyl)butanoate
    [catalogue_number] => PA 19 0481074
    [category_ids] => ,75,78,70,82,
    [chemical_name] => 
    [weight] => 275.27
    [form] => C13H16F3NO2
    [cas] => 1802495-69-7
    [pslug] => 1802495-69-7-isopropyl-r-3-amino-4-2-4-5-trifluorophenyl-butanoate-pa190481074
    [latest_product] => 0
    [linkproducts] => 0
    [offers_id] => 
    [offers_name] => 
    [offers_status] => 
    [offers_start_date] => 
    [offers_end_date] => 
    [pageview] => 
    [offers_slug] => 
    [offers_product_id] => 
    [offers_product_code] => 
    [offers_master_id] => 
    [offer_percentage] => 
    [offers_product_main_cat] => 
)
PA 19 0481074

Isopropyl (R)-3-amino-4-(2,4,5-trifluorophenyl)butanoate


  • Catalogue No.:PA 19 0481074

  • CAS :

    1802495-69-7

  • Molecular Formula : C13H16F3NO2

  • Molecular Weight : 275.27

stdClass Object
(
    [pname] => 3-Amino-4-(3,4-difluorophenyl)-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)butan-1-one
    [catalogue_number] => PA 19 0481075
    [category_ids] => ,70,78,82,
    [chemical_name] => 
    [weight] => 389.33
    [form] => C16H16F5N5O
    [cas] => 1334244-24-4
    [pslug] => 1334244-24-4-3-amino-4-3-4-difluorophenyl-1-3-trifluoromethyl-5-6-dihydro-1-2-4-triazolo-4-3-a-pyrazin-7-8h-yl-butan-1-one-pa190481075
    [latest_product] => 0
    [linkproducts] => 1
    [offers_id] => 
    [offers_name] => 
    [offers_status] => 
    [offers_start_date] => 
    [offers_end_date] => 
    [pageview] => 
    [offers_slug] => 
    [offers_product_id] => 
    [offers_product_code] => 
    [offers_master_id] => 
    [offer_percentage] => 
    [offers_product_main_cat] => 
)
PA 19 0481075

3-Amino-4-(3,4-difluorophenyl)-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)butan-1-one


  • Catalogue No.:PA 19 0481075

  • CAS :

    1334244-24-4

  • Molecular Formula : C16H16F5N5O

  • Molecular Weight : 389.33

stdClass Object
(
    [pname] => 1-(2,4,5-Trifluorophenyl)propan-2-amine Hydrochloride
    [catalogue_number] => PA 19 0481076
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 225.64
    [form] => C9H11ClF3N
    [cas] => 1062587-61-4
    [pslug] => 1062587-61-4-1-2-4-5-trifluorophenyl-propan-2-amine-hydrochloride-pa190481076
    [latest_product] => 0
    [linkproducts] => 1
    [offers_id] => 
    [offers_name] => 
    [offers_status] => 
    [offers_start_date] => 
    [offers_end_date] => 
    [pageview] => 
    [offers_slug] => 
    [offers_product_id] => 
    [offers_product_code] => 
    [offers_master_id] => 
    [offer_percentage] => 
    [offers_product_main_cat] => 
)
PA 19 0481076

1-(2,4,5-Trifluorophenyl)propan-2-amine Hydrochloride


  • Catalogue No.:PA 19 0481076

  • CAS :

    1062587-61-4

  • Molecular Formula : C9H11ClF3N

  • Molecular Weight : 225.64

stdClass Object
(
    [pname] => N-Nitroso Sitagliptin Fumarate Adduct
    [catalogue_number] => PA 19 0481080
    [category_ids] => ,75,76,78,82,
    [chemical_name] => 
    [weight] => 552.39
    [form] => C20H18F6N6O6
    [cas] => NA
    [pslug] => n-nitroso-sitagliptin-fumarate-adduct-pa190481080
    [latest_product] => 0
    [linkproducts] => 0
    [offers_id] => 
    [offers_name] => 
    [offers_status] => 
    [offers_start_date] => 
    [offers_end_date] => 
    [pageview] => 
    [offers_slug] => 
    [offers_product_id] => 
    [offers_product_code] => 
    [offers_master_id] => 
    [offer_percentage] => 
    [offers_product_main_cat] => 
)
PA 19 0481080

N-Nitroso Sitagliptin Fumarate Adduct


  • Catalogue No.:PA 19 0481080

  • CAS :

    NA

  • Molecular Formula : C20H18F6N6O6

  • Molecular Weight : 552.39

stdClass Object
(
    [pname] =>  Tert-butyl 3-amino-4-(2,4,5-trifluorophenyl)butanoate
    [catalogue_number] => PA 19 0481081
    [category_ids] => ,82,78,76,75,70,
    [chemical_name] => 
    [weight] => 289.3
    [form] => C14H18F3NO2
    [cas] => 1964462-19-8
    [pslug] => 1964462-19-8- tert-butyl-3-amino-4-2-4-5-trifluorophenyl-butanoate-pa190481081
    [latest_product] => 0
    [linkproducts] => 0
    [offers_id] => 
    [offers_name] => 
    [offers_status] => 
    [offers_start_date] => 
    [offers_end_date] => 
    [pageview] => 
    [offers_slug] => 
    [offers_product_id] => 
    [offers_product_code] => 
    [offers_master_id] => 
    [offer_percentage] => 
    [offers_product_main_cat] => 
)
PA 19 0481081

 Tert-butyl 3-amino-4-(2,4,5-trifluorophenyl)butanoate


  • Catalogue No.:PA 19 0481081

  • CAS :

    1964462-19-8

  • Molecular Formula : C14H18F3NO2

  • Molecular Weight : 289.3

stdClass Object
(
    [pname] => Tert-butyl (R)-3-((tert-butoxycarbonyl)amino)-4-(2,4,5-trifluorophenyl)butanoate
    [catalogue_number] => PA 19 0481082
    [category_ids] => ,82,78,76,75,70,
    [chemical_name] => 
    [weight] => 389.42
    [form] => C19H26F3NO4
    [cas] => 1246961-45-4
    [pslug] => 1246961-45-4-tert-butyl-r-3-tert-butoxycarbonyl-amino-4-2-4-5-trifluorophenyl-butanoate-pa190481082
    [latest_product] => 0
    [linkproducts] => 0
    [offers_id] => 
    [offers_name] => 
    [offers_status] => 
    [offers_start_date] => 
    [offers_end_date] => 
    [pageview] => 
    [offers_slug] => 
    [offers_product_id] => 
    [offers_product_code] => 
    [offers_master_id] => 
    [offer_percentage] => 
    [offers_product_main_cat] => 
)
PA 19 0481082

Tert-butyl (R)-3-((tert-butoxycarbonyl)amino)-4-(2,4,5-trifluorophenyl)butanoate


  • Catalogue No.:PA 19 0481082

  • CAS :

    1246961-45-4

  • Molecular Formula : C19H26F3NO4

  • Molecular Weight : 389.42

stdClass Object
(
    [pname] => (R)-3-((tert-Butoxycarbonyl)amino)-4-(2,3,6-trifluorophenyl)butanoic acid
    [catalogue_number] => PA 19 0481084
    [category_ids] => ,79,80,78,75,76,82,
    [chemical_name] => 
    [weight] => 333.31
    [form] => C15H18F3NO4
    [cas] => 611240-53-0
    [pslug] => 611240-53-0-r-3-tert-butoxycarbonyl-amino-4-2-3-6-trifluorophenyl-butanoic-acid-pa190481084
    [latest_product] => 0
    [linkproducts] => 0
    [offers_id] => 
    [offers_name] => 
    [offers_status] => 
    [offers_start_date] => 
    [offers_end_date] => 
    [pageview] => 
    [offers_slug] => 
    [offers_product_id] => 
    [offers_product_code] => 
    [offers_master_id] => 
    [offer_percentage] => 
    [offers_product_main_cat] => 
)
PA 19 0481084

(R)-3-((tert-Butoxycarbonyl)amino)-4-(2,3,6-trifluorophenyl)butanoic acid


  • Catalogue No.:PA 19 0481084

  • CAS :

    611240-53-0

  • Molecular Formula : C15H18F3NO4

  • Molecular Weight : 333.31

stdClass Object
(
    [pname] => (Z)-3-Amino-1-morpholino-4-(2,4,5-trifluorophenyl)but-2-en-1-one
    [catalogue_number] => PA 19 0481085
    [category_ids] => ,79,80,78,75,76,82,
    [chemical_name] => 
    [weight] => 300.28
    [form] => C14H15F3N2O2
    [cas] => NA
    [pslug] => z-3-amino-1-morpholino-4-2-4-5-trifluorophenyl-but-2-en-1-one-pa190481085
    [latest_product] => 0
    [linkproducts] => 0
    [offers_id] => 
    [offers_name] => 
    [offers_status] => 
    [offers_start_date] => 
    [offers_end_date] => 
    [pageview] => 
    [offers_slug] => 
    [offers_product_id] => 
    [offers_product_code] => 
    [offers_master_id] => 
    [offer_percentage] => 
    [offers_product_main_cat] => 
)
PA 19 0481085

(Z)-3-Amino-1-morpholino-4-(2,4,5-trifluorophenyl)but-2-en-1-one


  • Catalogue No.:PA 19 0481085

  • CAS :

    NA

  • Molecular Formula : C14H15F3N2O2

  • Molecular Weight : 300.28

stdClass Object
(
    [pname] => (R)-(R)-3-((tert-Butoxycarbonyl)amino)-4-(2,4,5-trifluorophenyl)butanoic N,N'-dicyclohexylcarbamimidic anhydride
    [catalogue_number] => PA 19 0481086
    [category_ids] => ,79,80,78,75,76,82,
    [chemical_name] => 
    [weight] => 539.64
    [form] => C28H40F3N3O4
    [cas] => 2072867-06-0
    [pslug] => 2072867-06-0-r-r-3-tert-butoxycarbonyl-amino-4-2-4-5-trifluorophenyl-butanoic-n-n-dicyclohexylcarbamimidic-anhydride-pa190481086
    [latest_product] => 0
    [linkproducts] => 0
    [offers_id] => 
    [offers_name] => 
    [offers_status] => 
    [offers_start_date] => 
    [offers_end_date] => 
    [pageview] => 
    [offers_slug] => 
    [offers_product_id] => 
    [offers_product_code] => 
    [offers_master_id] => 
    [offer_percentage] => 
    [offers_product_main_cat] => 
)
PA 19 0481086

(R)-(R)-3-((tert-Butoxycarbonyl)amino)-4-(2,4,5-trifluorophenyl)butanoic N,N'-dicyclohexylcarbamimidic anhydride


  • Catalogue No.:PA 19 0481086

  • CAS :

    2072867-06-0

  • Molecular Formula : C28H40F3N3O4

  • Molecular Weight : 539.64

stdClass Object
(
    [pname] => (R)-3-((tert-Butoxycarbonyl)amino)-4-(2,4,5-trifluorophenyl)butanoic Acid Triethylamine Salt
    [catalogue_number] => PA 19 0481090
    [category_ids] => ,79,80,78,70,82,
    [chemical_name] => 
    [weight] => 434.50
    [form] => C21H33F3N2O4
    [cas] => NA
    [pslug] => r-3-tert-butoxycarbonyl-amino-4-2-4-5-trifluorophenyl-butanoic-acid-triethylamine-salt-pa190481090
    [latest_product] => 0
    [linkproducts] => 1
    [offers_id] => 
    [offers_name] => 
    [offers_status] => 
    [offers_start_date] => 
    [offers_end_date] => 
    [pageview] => 
    [offers_slug] => 
    [offers_product_id] => 
    [offers_product_code] => 
    [offers_master_id] => 
    [offer_percentage] => 
    [offers_product_main_cat] => 
)
PA 19 0481090

(R)-3-((tert-Butoxycarbonyl)amino)-4-(2,4,5-trifluorophenyl)butanoic Acid Triethylamine Salt


  • Catalogue No.:PA 19 0481090

  • CAS :

    NA

  • Molecular Formula : C21H33F3N2O4

  • Molecular Weight : 434.50

stdClass Object
(
    [pname] => (S)-Sitagliptin N-Boc-Acid Impurity Triethylamine Salt
    [catalogue_number] => PA 19 0481092
    [category_ids] => ,79,80,78,70,82,
    [chemical_name] => 
    [weight] => 434.50
    [form] => C21H33F3N2O4
    [cas] => NA
    [pslug] => s-sitagliptin-n-boc-acid-impurity-triethylamine-salt-pa190481092
    [latest_product] => 0
    [linkproducts] => 1
    [offers_id] => 
    [offers_name] => 
    [offers_status] => 
    [offers_start_date] => 
    [offers_end_date] => 
    [pageview] => 
    [offers_slug] => 
    [offers_product_id] => 
    [offers_product_code] => 
    [offers_master_id] => 
    [offer_percentage] => 
    [offers_product_main_cat] => 
)
PA 19 0481092

(S)-Sitagliptin N-Boc-Acid Impurity Triethylamine Salt


  • Catalogue No.:PA 19 0481092

  • CAS :

    NA

  • Molecular Formula : C21H33F3N2O4

  • Molecular Weight : 434.50

stdClass Object
(
    [pname] => N,N-Diisopropyl-3-oxo-4-(2,4,5-trifluorophenyl)butanamide
    [catalogue_number] => PA 19 0481093
    [category_ids] => ,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 315.34
    [form] => C16H20F3NO2
    [cas] => NA
    [pslug] => n-n-diisopropyl-3-oxo-4-2-4-5-trifluorophenyl-butanamide-pa190481093
    [latest_product] => 0
    [linkproducts] => 0
    [offers_id] => 
    [offers_name] => 
    [offers_status] => 
    [offers_start_date] => 
    [offers_end_date] => 
    [pageview] => 
    [offers_slug] => 
    [offers_product_id] => 
    [offers_product_code] => 
    [offers_master_id] => 
    [offer_percentage] => 
    [offers_product_main_cat] => 
)
PA 19 0481093

N,N-Diisopropyl-3-oxo-4-(2,4,5-trifluorophenyl)butanamide


  • Catalogue No.:PA 19 0481093

  • CAS :

    NA

  • Molecular Formula : C16H20F3NO2

  • Molecular Weight : 315.34

stdClass Object
(
    [pname] => (R)-10-(2,4,5-Trifluorobenzyl)-3-(trifluoromethyl)-5,6,9,10-tetrahydro-8H-[1,2,4]triazolo[3',4':3,4]pyrazino[1,2-a]pyrimidin-8-one
    [catalogue_number] => PA 19 0481094
    [category_ids] => ,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 403.29
    [form] => C16H11F6N5O
    [cas] => 2821750-76-7
    [pslug] => 2821750-76-7-r-10-2-4-5-trifluorobenzyl-3-trifluoromethyl-5-6-9-10-tetrahydro-8h-1-2-4-triazolo-3-4-3-4-pyrazino-1-2-a-pyrimidin-8-one-pa190481094
    [latest_product] => 0
    [linkproducts] => 0
    [offers_id] => 
    [offers_name] => 
    [offers_status] => 
    [offers_start_date] => 
    [offers_end_date] => 
    [pageview] => 
    [offers_slug] => 
    [offers_product_id] => 
    [offers_product_code] => 
    [offers_master_id] => 
    [offer_percentage] => 
    [offers_product_main_cat] => 
)
PA 19 0481094

(R)-10-(2,4,5-Trifluorobenzyl)-3-(trifluoromethyl)-5,6,9,10-tetrahydro-8H-[1,2,4]triazolo[3',4':3,4]pyrazino[1,2-a]pyrimidin-8-one


  • Catalogue No.:PA 19 0481094

  • CAS :

    2821750-76-7

  • Molecular Formula : C16H11F6N5O

  • Molecular Weight : 403.29