Ibrutinib is used to treat chronic lymphocytic leukemia Waldenström's macroglobulinemia, and as a second-line treatment for mantle cell lymphoma, marginal zone lymphoma, and chronic graft vs host disease. It is a small molecule drug. Reference standards of Ibrutinib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
stdClass Object ( [pname] => 1,3-bis((R)-3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)propan-1-one [catalogue_number] => PA 09 27510 [category_ids] => ,71,79,80,81,75,78,70,82, [chemical_name] => [weight] => 826.95 [form] => C47H46N12O3 [cas] => 1987905-93-0 [pslug] => 1987905-93-0-1-3-bis-r-3-4-amino-3-4-phenoxyphenyl-1h-pyrazolo-3-4-d-pyrimidin-1-yl-piperidin-1-yl-propan-1-one-pa0927510 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 09 27510
CAS :
Molecular Formula : C47H46N12O3
Molecular Weight : 826.95
stdClass Object ( [pname] => (R)-3-(3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-3-oxopropyl Acrylate [catalogue_number] => PA 09 27520 [category_ids] => ,71,79,80,81,75,78,70,82, [chemical_name] => [weight] => 512.56 [form] => C28H28N6O4 [cas] => 2244619-11-0 [pslug] => 2244619-11-0-r-3-3-4-amino-3-4-phenoxyphenyl-1h-pyrazolo-3-4-d-pyrimidin-1-yl-piperidin-1-yl-3-oxopropyl-acrylate-pa0927520 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 09 27520
Molecular Formula : C28H28N6O4
Molecular Weight : 512.56
stdClass Object ( [pname] => 1-[(3R)-3-[4-Amino-3-(4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidyl]-3-[[(1R)-3-(4-phenoxyphenyl)-1-(1-prop-2-enoyl-3-piperidyl)pyrazolo[3,4-d]pyrimidin-4-yl]amino]propan-1-one [catalogue_number] => PA 09 27530 [category_ids] => 82,81,80,79,78,75,71,70 [chemical_name] => [weight] => 880.99 [form] => C50H48N12O4 [cas] => 2031255-23-7 [pslug] => 2031255-23-7-1-3r-3-4-amino-3-4-phenoxyphenyl-pyrazolo-3-4-d-pyrimidin-1-yl-1-piperidyl-3-1r-3-4-phenoxyphenyl-1-1-prop-2-enoyl-3-piperidyl-pyrazolo-3-4-d-pyrimidin-4-yl-amino-propan-1-one-pa0927530 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 09 27530
Molecular Formula : C50H48N12O4
Molecular Weight : 880.99
stdClass Object ( [pname] => N-(1-((S)-1-Acryloylpiperidin-3-yl)-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-3-((S)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)propanamide [catalogue_number] => PA 09 27580 [category_ids] => ,79,80,81,71, [chemical_name] => [weight] => 881.01 [form] => C50H48N12O4 [cas] => NA [pslug] => n-1-s-1-acryloylpiperidin-3-yl-3-4-phenoxyphenyl-1h-pyrazolo-3-4-d-pyrimidin-4-yl-3-s-3-4-amino-3-4-phenoxyphenyl-1h-pyrazolo-3-4-d-pyrimidin-1-yl-piperidin-1-yl-propanamide-pa0927580 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 09 27580
Molecular Weight : 881.01
stdClass Object ( [pname] => 1-(1-Nitrosopiperidin-3-yl)-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine [catalogue_number] => PA 09 0271021 [category_ids] => ,70,71,78,82,162, [chemical_name] => [weight] => 415.46 [form] => C22H21N7O2 [cas] => 2256059-43-3 [pslug] => 2256059-43-3-1-1-nitrosopiperidin-3-yl-3-4-phenoxyphenyl-1h-pyrazolo-3-4-d-pyrimidin-4-amine-pa090271021 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 09 0271021
Molecular Formula : C22H21N7O2
Molecular Weight : 415.46
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