Apixaban-impurities | Pharmaffiliates

apixaban

Apixaban, sold under the trade name Eliquis among others, is an anticoagulant used to treat and prevent blood clots and to prevent stroke in people with nonvalvular atrial fibrillation.. Reference standards of Apixaban API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below

stdClass Object
(
    [pname] => 1-(4-Aminophenyl)piperidin-2-one
    [catalogue_number] => PA 28 0111062
    [category_ids] => ,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 190.25
    [form] => C11H14N2O
    [cas] => 438056-68-9
    [pslug] => 438056-68-9-1-4-aminophenyl-piperidin-2-one-pa280111062
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PA 28 0111062

1-(4-Aminophenyl)piperidin-2-one


  • Catalogue No.:PA 28 0111062

  • CAS :

    438056-68-9

  • Molecular Formula : C11H14N2O

  • Molecular Weight : 190.25

stdClass Object
(
    [pname] => Ethyl (Z)-2-chloro-2-(2-(4-methoxyphenyl)hydrazineylidene)acetate
    [catalogue_number] => PA 28 0111063
    [category_ids] => 82,78,70
    [chemical_name] => 
    [weight] => 256.69
    [form] => C11H13ClN2O3
    [cas] => 473927-63-8
    [pslug] => 473927-63-8-ethyl-z-2-chloro-2-2-4-methoxyphenyl-hydrazineylidene-acetate-pa280111063
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PA 28 0111063

Ethyl (Z)-2-chloro-2-(2-(4-methoxyphenyl)hydrazineylidene)acetate


  • Catalogue No.:PA 28 0111063

  • CAS :

    473927-63-8

  • Molecular Formula : C11H13ClN2O3

  • Molecular Weight : 256.69

stdClass Object
(
    [pname] => 1-(4-Methoxyphenyl)-4-(2-(nitroso(4-(2-oxopiperidin-1-yl)phenyl)amino)ethyl)-1H-pyrazole-3,5-dicarboxamide
    [catalogue_number] => PA 28 0111064
    [category_ids] => ,78,70,82,
    [chemical_name] => 
    [weight] => 505.54
    [form] => C25H27N7O5
    [cas] => NA
    [pslug] => 1-4-methoxyphenyl-4-2-nitroso-4-2-oxopiperidin-1-yl-phenyl-amino-ethyl-1h-pyrazole-3-5-dicarboxamide-pa280111064
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PA 28 0111064

1-(4-Methoxyphenyl)-4-(2-(nitroso(4-(2-oxopiperidin-1-yl)phenyl)amino)ethyl)-1H-pyrazole-3,5-dicarboxamide


  • Catalogue No.:PA 28 0111064

  • CAS :

    NA

  • Molecular Formula : C25H27N7O5

  • Molecular Weight : 505.54

stdClass Object
(
    [pname] => Ethyl 1-(2-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate
    [catalogue_number] => PA 28 0111065
    [category_ids] => ,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 488.54
    [form] => C27H28N4O5
    [cas] => 1801881-20-8
    [pslug] => 1801881-20-8-ethyl-1-2-methoxyphenyl-7-oxo-6-4-2-oxopiperidin-1-yl-phenyl-4-5-6-7-tetrahydro-1h-pyrazolo-3-4-c-pyridine-3-carboxylate-pa280111065
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PA 28 0111065

Ethyl 1-(2-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate


  • Catalogue No.:PA 28 0111065

  • CAS :

    1801881-20-8

  • Molecular Formula : C27H28N4O5

  • Molecular Weight : 488.54

stdClass Object
(
    [pname] => Ethyl 7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-1-phenyl-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate
    [catalogue_number] => PA 28 0111066
    [category_ids] => ,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 458.52
    [form] => C26H26N4O4
    [cas] => 1801881-21-9
    [pslug] => 1801881-21-9-ethyl-7-oxo-6-4-2-oxopiperidin-1-yl-phenyl-1-phenyl-4-5-6-7-tetrahydro-1h-pyrazolo-3-4-c-pyridine-3-carboxylate-pa280111066
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PA 28 0111066

Ethyl 7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-1-phenyl-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate


  • Catalogue No.:PA 28 0111066

  • CAS :

    1801881-21-9

  • Molecular Formula : C26H26N4O4

  • Molecular Weight : 458.52

stdClass Object
(
    [pname] => 5-((4-(5-Morpholino-6-oxo-3,6-dihydropyridin-1(2H)-yl)phenyl)(nitroso)amino)pentanoic Acid
    [catalogue_number] => PA 28 0111067
    [category_ids] => ,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 402.45
    [form] => C20H26N4O5
    [cas] => NA
    [pslug] => 5-4-5-morpholino-6-oxo-3-6-dihydropyridin-1-2h-yl-phenyl-nitroso-amino-pentanoic-acid-pa280111067
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PA 28 0111067

5-((4-(5-Morpholino-6-oxo-3,6-dihydropyridin-1(2H)-yl)phenyl)(nitroso)amino)pentanoic Acid


  • Catalogue No.:PA 28 0111067

  • CAS :

    NA

  • Molecular Formula : C20H26N4O5

  • Molecular Weight : 402.45

stdClass Object
(
    [pname] => 5-Chloro-N-(4-(5-morpholino-6-oxo-3,6-dihydropyridin-1(2H)-yl)phenyl)-N-nitrosopentanamide
    [catalogue_number] => PA 28 0111068
    [category_ids] => ,80,71,81,78,70,82,162,
    [chemical_name] => 
    [weight] => 420.89
    [form] => C20H25ClN4O4
    [cas] => NA
    [pslug] => 5-chloro-n-4-5-morpholino-6-oxo-3-6-dihydropyridin-1-2h-yl-phenyl-n-nitrosopentanamide-pa280111068
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PA 28 0111068

5-Chloro-N-(4-(5-morpholino-6-oxo-3,6-dihydropyridin-1(2H)-yl)phenyl)-N-nitrosopentanamide


  • Catalogue No.:PA 28 0111068

  • CAS :

    NA

  • Molecular Formula : C20H25ClN4O4

  • Molecular Weight : 420.89

stdClass Object
(
    [pname] => 6-(4-((4-Carboxybutyl)amino)phenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic Acid
    [catalogue_number] => PA 28 0111069
    [category_ids] => ,75,78,79,82,
    [chemical_name] => 
    [weight] => 478.51
    [form] => C25H26N4O6
    [cas] => 2264018-89-3
    [pslug] => 2264018-89-3-6-4-4-carboxybutyl-amino-phenyl-1-4-methoxyphenyl-7-oxo-4-5-6-7-tetrahydro-1h-pyrazolo-3-4-c-pyridine-3-carboxylic-acid-pa280111069
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PA 28 0111069

6-(4-((4-Carboxybutyl)amino)phenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic Acid


  • Catalogue No.:PA 28 0111069

  • CAS :

    2264018-89-3

  • Molecular Formula : C25H26N4O6

  • Molecular Weight : 478.51

stdClass Object
(
    [pname] => 1-(4-Methoxyphenyl)-4-(2-((4-(2-oxopiperidin-1-yl)phenyl)amino)ethyl)-1H-pyrazole-3,5-dicarboxylic Acid
    [catalogue_number] => PA 28 0111070
    [category_ids] => ,75,78,79,82,
    [chemical_name] => 
    [weight] => 478.51
    [form] => C25H26N4O6
    [cas] => NA
    [pslug] => 1-4-methoxyphenyl-4-2-4-2-oxopiperidin-1-yl-phenyl-amino-ethyl-1h-pyrazole-3-5-dicarboxylic-acid-pa280111070
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PA 28 0111070

1-(4-Methoxyphenyl)-4-(2-((4-(2-oxopiperidin-1-yl)phenyl)amino)ethyl)-1H-pyrazole-3,5-dicarboxylic Acid


  • Catalogue No.:PA 28 0111070

  • CAS :

    NA

  • Molecular Formula : C25H26N4O6

  • Molecular Weight : 478.51

stdClass Object
(
    [pname] => N-(4-(5-Morpholino-6-oxo-3,6-dihydropyridin-1(2H)-yl)phenyl)formamide
    [catalogue_number] => PA 28 0111071
    [category_ids] => ,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 301.35
    [form] => C16H19N3O3
    [cas] => NA
    [pslug] => n-4-5-morpholino-6-oxo-3-6-dihydropyridin-1-2h-yl-phenyl-formamide-pa280111071
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PA 28 0111071

N-(4-(5-Morpholino-6-oxo-3,6-dihydropyridin-1(2H)-yl)phenyl)formamide


  • Catalogue No.:PA 28 0111071

  • CAS :

    NA

  • Molecular Formula : C16H19N3O3

  • Molecular Weight : 301.35

stdClass Object
(
    [pname] => 3-Morpholino-1-(3-(2-oxopiperidin-1-yl)phenyl)piperidin-2-one
    [catalogue_number] => PA 28 0111072
    [category_ids] => ,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 357.45
    [form] => C20H27N3O3
    [cas] => NA
    [pslug] => 3-morpholino-1-3-2-oxopiperidin-1-yl-phenyl-piperidin-2-one-pa280111072
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PA 28 0111072

3-Morpholino-1-(3-(2-oxopiperidin-1-yl)phenyl)piperidin-2-one


  • Catalogue No.:PA 28 0111072

  • CAS :

    NA

  • Molecular Formula : C20H27N3O3

  • Molecular Weight : 357.45

stdClass Object
(
    [pname] => 3-Morpholino-1-(2-(2-oxopiperidin-1-yl)phenyl)piperidin-2-one
    [catalogue_number] => PA 28 0111073
    [category_ids] => ,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 357.45
    [form] => C20H27N3O3
    [cas] => NA
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PA 28 0111073

3-Morpholino-1-(2-(2-oxopiperidin-1-yl)phenyl)piperidin-2-one


  • Catalogue No.:PA 28 0111073

  • CAS :

    NA

  • Molecular Formula : C20H27N3O3

  • Molecular Weight : 357.45

stdClass Object
(
    [pname] => Ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-6,7-dihydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate
    [catalogue_number] => PA 28 0111074
    [category_ids] => ,80,71,81,78,70,82,
    [chemical_name] => 
    [weight] => 486.53
    [form] => C27H26N4O5
    [cas] => 2514951-00-7
    [pslug] => 2514951-00-7-ethyl-1-4-methoxyphenyl-7-oxo-6-4-2-oxopiperidin-1-yl-phenyl-6-7-dihydro-1h-pyrazolo-3-4-c-pyridine-3-carboxylate-pa280111074
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PA 28 0111074

Ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-6,7-dihydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate


  • Catalogue No.:PA 28 0111074

  • CAS :

    2514951-00-7

  • Molecular Formula : C27H26N4O5

  • Molecular Weight : 486.53

stdClass Object
(
    [pname] => 3-Morpholino-1-(3-(2-oxopiperidin-1-yl)phenyl)-5,6-dihydropyridin-2(1H)-one
    [catalogue_number] => PA 28 0111075
    [category_ids] => ,78,70,82,
    [chemical_name] => 
    [weight] => 355.44
    [form] => C20H25N3O3
    [cas] => NA
    [pslug] => 3-morpholino-1-3-2-oxopiperidin-1-yl-phenyl-5-6-dihydropyridin-2-1h-one-pa280111075
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PA 28 0111075

3-Morpholino-1-(3-(2-oxopiperidin-1-yl)phenyl)-5,6-dihydropyridin-2(1H)-one


  • Catalogue No.:PA 28 0111075

  • CAS :

    NA

  • Molecular Formula : C20H25N3O3

  • Molecular Weight : 355.44

stdClass Object
(
    [pname] => 3-Morpholino-1-(2-(2-oxopiperidin-1-yl)phenyl)-5,6-dihydropyridin-2(1H)-one
    [catalogue_number] => PA 28 0111076
    [category_ids] => ,78,70,82,
    [chemical_name] => 
    [weight] => 355.44
    [form] => C20H25N3O3
    [cas] => NA
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PA 28 0111076

3-Morpholino-1-(2-(2-oxopiperidin-1-yl)phenyl)-5,6-dihydropyridin-2(1H)-one


  • Catalogue No.:PA 28 0111076

  • CAS :

    NA

  • Molecular Formula : C20H25N3O3

  • Molecular Weight : 355.44