Linsitinib and its Impurities

Linsitinib is an experimental drug candidate for the treatment of various types of cancer. It is an inhibitor of the insulin receptor and of the insulin-like growth factor 1 receptor. This prevents tumor cell proliferation and induces tumor cell apoptosis. Reference standards of Linsitinib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.