Apalutamide-impurities | Pharmaffiliates

Apalutamide

Apalutamide, sold under the brand name Erleada among others, is a nonsteroidal antiandrogen medication which is used in the treatment of prostate cancer. It is specifically indicated for use in conjunction with castration in the treatment of non-metastatic castration-resistant prostate cancer Reference standards of Apalutamide API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
(
    [pname] => 5-Amino-3-(trifluoromethyl)pyridine-2-carbonitrile
    [catalogue_number] => PA 01 2921011
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 187.13
    [form] => C7H4F3N3
    [cas] => 573762-62-6
    [pslug] => 573762-62-6-5-amino-3-trifluoromethyl-pyridine-2-carbonitrile-pa012921011
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PA 01 2921011

5-Amino-3-(trifluoromethyl)pyridine-2-carbonitrile


  • Catalogue No.:PA 01 2921011

  • CAS :

    573762-62-6

  • Molecular Formula : C7H4F3N3

  • Molecular Weight : 187.13

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stdClass Object
(
    [pname] => 2-Bromo-5-Nitro-3-(Trifluoromethyl)Pyridine
    [catalogue_number] => PA 01 2921012
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 270.99
    [form] => C6H2BrF3N2O2
    [cas] => 956104-42-0
    [pslug] => 956104-42-0-2-bromo-5-nitro-3-trifluoromethyl-pyridine-pa012921012
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    [offers_product_code] => PA 01 2921012
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PA 01 2921012

2-Bromo-5-Nitro-3-(Trifluoromethyl)Pyridine


  • Catalogue No.:PA 01 2921012

  • CAS :

    956104-42-0

  • Molecular Formula : C6H2BrF3N2O2

  • Molecular Weight : 270.99

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stdClass Object
(
    [pname] => Apalutamide - API Standards 
    [catalogue_number] => PA 01 2920000
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 477.44
    [form] => C21H15F4N5O2S
    [cas] => 956104-40-8
    [pslug] => 956104-40-8-apalutamide-api-pa012920000
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PA 01 2920000

Apalutamide - API Standards


  • Catalogue No.:PA 01 2920000

  • CAS :

    956104-40-8

  • Molecular Formula : C21H15F4N5O2S

  • Molecular Weight : 477.44

stdClass Object
(
    [pname] => 4-(7-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluorobenzamide
    [catalogue_number] => PA 01 2921000
    [category_ids] => ,70,75,76,78,82,
    [chemical_name] => 
    [weight] => 463.41
    [form] => C20H13F4N5O2S
    [cas] => 1332391-11-3
    [pslug] => 1332391-11-3-4-7-6-cyano-5-trifluoromethyl-pyridin-3-yl-8-oxo-6-thioxo-5-7-diazaspiro-3-4-octan-5-yl-2-fluorobenzamide-pa012921000
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PA 01 2921000

4-(7-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluorobenzamide


  • Catalogue No.:PA 01 2921000

  • CAS :

    1332391-11-3

  • Molecular Formula : C20H13F4N5O2S

  • Molecular Weight : 463.41

stdClass Object
(
    [pname] => 4-((1-Cyanocyclobutyl)amino)-2-fluoro-N-methylbenzamide
    [catalogue_number] => PA 01 2921004
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 247.27
    [form] => C13H14FN3O
    [cas] => 915087-26-2
    [pslug] => 915087-26-2-4-1-cyanocyclobutyl-amino-2-fluoro-n-methylbenzamide-pa012921004
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PA 01 2921004

4-((1-Cyanocyclobutyl)amino)-2-fluoro-N-methylbenzamide


  • Catalogue No.:PA 01 2921004

  • CAS :

    915087-26-2

  • Molecular Formula : C13H14FN3O

  • Molecular Weight : 247.27

stdClass Object
(
    [pname] => 4-((1-((6-Cyano-5-(trifluoromethyl)pyridin-3-yl)carbamoyl)cyclobutyl)amino)-2-fluoro-N-methylbenzamide
    [catalogue_number] => PA 01 2921005
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 435.38
    [form] => C20H17F4N5O2
    [cas] => 1950587-20-8
    [pslug] => 1950587-20-8-4-1-6-cyano-5-trifluoromethyl-pyridin-3-yl-carbamoyl-cyclobutyl-amino-2-fluoro-n-methylbenzamide-pa012921005
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PA 01 2921005

4-((1-((6-Cyano-5-(trifluoromethyl)pyridin-3-yl)carbamoyl)cyclobutyl)amino)-2-fluoro-N-methylbenzamide


  • Catalogue No.:PA 01 2921005

  • CAS :

    1950587-20-8

  • Molecular Formula : C20H17F4N5O2

  • Molecular Weight : 435.38

stdClass Object
(
    [pname] => 1-[3-Fluoro-4-(methylcarbamoyl)anilino]cyclobutane-1-carboxylic acid
    [catalogue_number] => PA 01 2921006
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 266.27
    [form] => C13H15FN2O3
    [cas] => 2227589-22-0
    [pslug] => 2227589-22-0-1-3-fluoro-4-methylcarbamoyl-anilino-cyclobutane-1-carboxylic-acid-pa012921006
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PA 01 2921006

1-[3-Fluoro-4-(methylcarbamoyl)anilino]cyclobutane-1-carboxylic acid


  • Catalogue No.:PA 01 2921006

  • CAS :

    2227589-22-0

  • Molecular Formula : C13H15FN2O3

  • Molecular Weight : 266.27

stdClass Object
(
    [pname] => 1-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)thiourea
    [catalogue_number] => PA 01 2921007
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 246.21
    [form] => C8H5F3N4S
    [cas] => 2422147-84-8
    [pslug] => 2422147-84-8-1-6-cyano-5-trifluoromethyl-pyridin-3-yl-thiourea-pa012921007
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PA 01 2921007

1-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)thiourea


  • Catalogue No.:PA 01 2921007

  • CAS :

    2422147-84-8

  • Molecular Formula : C8H5F3N4S

  • Molecular Weight : 246.21

stdClass Object
(
    [pname] => 4-(7-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3,4]octan-5-yl)-2-fluorobenzoic acid
    [catalogue_number] => PA 01 2921008
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 464.39
    [form] => C20H12F4N4O3S
    [cas] => 1332391-04-4
    [pslug] => 1332391-04-4-4-7-6-cyano-5-trifluoromethyl-pyridin-3-yl-8-oxo-6-thioxo-5-7-diazaspiro-3-4-octan-5-yl-2-fluorobenzoic-acid-pa012921008
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PA 01 2921008

4-(7-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3,4]octan-5-yl)-2-fluorobenzoic acid


  • Catalogue No.:PA 01 2921008

  • CAS :

    1332391-04-4

  • Molecular Formula : C20H12F4N4O3S

  • Molecular Weight : 464.39

stdClass Object
(
    [pname] => Apalutamide D3
    [catalogue_number] => PA STI 088917
    [category_ids] => ,98,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 480.46
    [form] => C21H12D3F4N5O2S
    [cas] => 1638885-61-6
    [pslug] => 1638885-61-6-apalutamide-d3-pasti088917
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PA STI 088917

Apalutamide D3


  • Catalogue No.:PA STI 088917

  • CAS :

    1638885-61-6

  • Molecular Formula : C21H12D3F4N5O2S

  • Molecular Weight : 480.46

stdClass Object
(
    [pname] => 4-(7-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluoro-N-(methyl-13C-d3)benzamide
    [catalogue_number] => PA STI 088918
    [category_ids] => ,98,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 481.45
    [form] => C2013CH12D3F4N5O2S
    [cas] => NA
    [pslug] => 4-7-6-cyano-5-trifluoromethyl-pyridin-3-yl-8-oxo-6-thioxo-5-7-diazaspiro-3-4-octan-5-yl-2-fluoro-n-methyl-13c-d3-benzamide-pasti088918
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PA STI 088918

4-(7-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluoro-N-(methyl-13C-d3)benzamide


  • Catalogue No.:PA STI 088918

  • CAS :

    NA

  • Molecular Formula : C2013CH12D3F4N5O2S

  • Molecular Weight : 481.45

stdClass Object
(
    [pname] => 4-(7-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-N-methylbenzamide
    [catalogue_number] => PA 01 2921009
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 459.45
    [form] => C21H16F3N5O2S
    [cas] => 1332389-57-7
    [pslug] => 1332389-57-7-4-7-6-cyano-5-trifluoromethyl-pyridin-3-yl-8-oxo-6-thioxo-5-7-diazaspiro-3-4-octan-5-yl-n-methylbenzamide-pa012921009
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PA 01 2921009

4-(7-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-N-methylbenzamide


  • Catalogue No.:PA 01 2921009

  • CAS :

    1332389-57-7

  • Molecular Formula : C21H16F3N5O2S

  • Molecular Weight : 459.45

stdClass Object
(
    [pname] => 2-Fluoro-4-(hydroxyamino)-N-methylbenzamide
    [catalogue_number] => PA 01 2921010
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 184.17
    [form] => C8H9FN2O2
    [cas] => NA
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PA 01 2921010

2-Fluoro-4-(hydroxyamino)-N-methylbenzamide


  • Catalogue No.:PA 01 2921010

  • CAS :

    NA

  • Molecular Formula : C8H9FN2O2

  • Molecular Weight : 184.17

stdClass Object
(
    [pname] => 4-Amino-N-methylbenzamide
    [catalogue_number] => PA 01 2921013
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 150.18
    [form] => C8H10N2O
    [cas] => 6274-22-2
    [pslug] => 6274-22-2-4-amino-n-methylbenzamide-pa012921013
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PA 01 2921013

4-Amino-N-methylbenzamide


  • Catalogue No.:PA 01 2921013

  • CAS :

    6274-22-2

  • Molecular Formula : C8H10N2O

  • Molecular Weight : 150.18

stdClass Object
(
    [pname] => 2-Fluoro-4-nitrotoluene
    [catalogue_number] => PA 01 2921014
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 155.13
    [form] => C7H6FNO2
    [cas] => 1427-07-2
    [pslug] => 1427-07-2-2-fluoro-4-nitrotoluene-pa012921014
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PA 01 2921014

2-Fluoro-4-nitrotoluene


  • Catalogue No.:PA 01 2921014

  • CAS :

    1427-07-2

  • Molecular Formula : C7H6FNO2

  • Molecular Weight : 155.13

stdClass Object
(
    [pname] => 4-Amino-2-fluorobenzoic Acid
    [catalogue_number] => PA 01 2921015
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 155.13
    [form] => C7H6FNO2
    [cas] => 446-31-1
    [pslug] => 446-31-1-4-amino-2-fluorobenzoic-acid-pa012921015
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PA 01 2921015

4-Amino-2-fluorobenzoic Acid


  • Catalogue No.:PA 01 2921015

  • CAS :

    446-31-1

  • Molecular Formula : C7H6FNO2

  • Molecular Weight : 155.13

stdClass Object
(
    [pname] => O-Phenyl (4-(7-(6-cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluorobenzoyl)(methyl)carbamothioate
    [catalogue_number] => PA 01 2921017
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 613.61
    [form] => C28H19F4N5O3S2
    [cas] => NA
    [pslug] => o-phenyl-4-7-6-cyano-5-trifluoromethyl-pyridin-3-yl-8-oxo-6-thioxo-5-7-diazaspiro-3-4-octan-5-yl-2-fluorobenzoyl-methyl-carbamothioate-pa012921017
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PA 01 2921017

O-Phenyl (4-(7-(6-cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluorobenzoyl)(methyl)carbamothioate


  • Catalogue No.:PA 01 2921017

  • CAS :

    NA

  • Molecular Formula : C28H19F4N5O3S2

  • Molecular Weight : 613.61

stdClass Object
(
    [pname] => 4-(7-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-N-(1-((6-cyano-5-(trifluoromethyl)pyridin-3-yl)carbamoyl)cyclobutyl)-2-fluoro-N-(3-fluoro-4-(methylcarbamoyl)phenyl)benzamide
    [catalogue_number] => PA 01 2921016
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 881.76
    [form] => C40H27F8N9O4S
    [cas] => NA
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PA 01 2921016

4-(7-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-N-(1-((6-cyano-5-(trifluoromethyl)pyridin-3-yl)carbamoyl)cyclobutyl)-2-fluoro-N-(3-fluoro-4-(methylcarbamoyl)phenyl)benzamide


  • Catalogue No.:PA 01 2921016

  • CAS :

    NA

  • Molecular Formula : C40H27F8N9O4S

  • Molecular Weight : 881.76

stdClass Object
(
    [pname] => 1-((3-fluoro-4-(methylcarbamoyl)phenyl)amino)Cyclobutane-1-Carboxylic Acid, Potassium Salt (1:1)
    [catalogue_number] => PA 01 2921018
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 304.36
    [form] => C13H14FKN2O3
    [cas] => 2408380-71-0
    [pslug] => 2408380-71-0-1-3-fluoro-4-methylcarbamoyl-phenyl-amino-cyclobutane-1-carboxylic-acid-potassium-salt-1-1-pa012921018
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PA 01 2921018

1-((3-fluoro-4-(methylcarbamoyl)phenyl)amino)Cyclobutane-1-Carboxylic Acid, Potassium Salt (1:1)


  • Catalogue No.:PA 01 2921018

  • CAS :

    2408380-71-0

  • Molecular Formula : C13H14FKN2O3

  • Molecular Weight : 304.36

stdClass Object
(
    [pname] => Sodium 4-(7-(6-cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluorobenzoate
    [catalogue_number] => PA 01 2921019
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 486.38
    [form] => C20H11F4N4NaO3S
    [cas] => NA
    [pslug] => sodium-4-7-6-cyano-5-trifluoromethyl-pyridin-3-yl-8-oxo-6-thioxo-5-7-diazaspiro-3-4-octan-5-yl-2-fluorobenzoate-pa012921019
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PA 01 2921019

Sodium 4-(7-(6-cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluorobenzoate


  • Catalogue No.:PA 01 2921019

  • CAS :

    NA

  • Molecular Formula : C20H11F4N4NaO3S

  • Molecular Weight : 486.38

stdClass Object
(
    [pname] => Methyl 4-(7-(6-cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluorobenzoate
    [catalogue_number] => PA 01 2921020
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 478.42
    [form] => C21H14F4N4O3S
    [cas] => 1950587-19-5
    [pslug] => 1950587-19-5-methyl-4-7-6-cyano-5-trifluoromethyl-pyridin-3-yl-8-oxo-6-thioxo-5-7-diazaspiro-3-4-octan-5-yl-2-fluorobenzoate-pa012921020
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PA 01 2921020

Methyl 4-(7-(6-cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluorobenzoate


  • Catalogue No.:PA 01 2921020

  • CAS :

    1950587-19-5

  • Molecular Formula : C21H14F4N4O3S

  • Molecular Weight : 478.42

stdClass Object
(
    [pname] => Ethyl 4-(7-(6-cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluorobenzoate
    [catalogue_number] => PA 01 2921021
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 492.45
    [form] => C22H16F4N4O3S
    [cas] => 1332388-83-6
    [pslug] => 1332388-83-6-ethyl-4-7-6-cyano-5-trifluoromethyl-pyridin-3-yl-8-oxo-6-thioxo-5-7-diazaspiro-3-4-octan-5-yl-2-fluorobenzoate-pa012921021
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PA 01 2921021

Ethyl 4-(7-(6-cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluorobenzoate


  • Catalogue No.:PA 01 2921021

  • CAS :

    1332388-83-6

  • Molecular Formula : C22H16F4N4O3S

  • Molecular Weight : 492.45

stdClass Object
(
    [pname] => 4-((1-Cyanocyclobutyl)(nitroso)amino)-2-fluoro-N-methylbenzamide
    [catalogue_number] => PA 01 2921023
    [category_ids] => ,70,75,76,78,82,162,
    [chemical_name] => 
    [weight] => 276.27
    [form] => C13H13FN4O2
    [cas] => NA
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PA 01 2921023

4-((1-Cyanocyclobutyl)(nitroso)amino)-2-fluoro-N-methylbenzamide


  • Catalogue No.:PA 01 2921023

  • CAS :

    NA

  • Molecular Formula : C13H13FN4O2

  • Molecular Weight : 276.27

stdClass Object
(
    [pname] => 4-(7-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluoro-N-(3-fluoro-4-(methylcarbamoyl)phenyl)-N-methylbenzamide
    [catalogue_number] => PA 01 2921024
    [category_ids] => 76,82,78,70,75
    [chemical_name] => 
    [weight] => 628.58
    [form] => C29H21F5N6O3S
    [cas] => 2894796-76-8
    [pslug] => 2894796-76-8-4-7-6-cyano-5-trifluoromethyl-pyridin-3-yl-8-oxo-6-thioxo-5-7-diazaspiro-3-4-octan-5-yl-2-fluoro-n-3-fluoro-4-methylcarbamoyl-phenyl-n-methylbenzamide-pa012921024
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PA 01 2921024

4-(7-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluoro-N-(3-fluoro-4-(methylcarbamoyl)phenyl)-N-methylbenzamide


  • Catalogue No.:PA 01 2921024

  • CAS :

    2894796-76-8

  • Molecular Formula : C29H21F5N6O3S

  • Molecular Weight : 628.58