Asciminib
Asciminib, sold under the brand name Scemblix, is a medication used to treat Philadelphia chromosome-positive chronic myeloid leukemia. It is a protein kinase inhibitor. Reference standards of Asciminib API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
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[pname] => Asciminib
[catalogue_number] => PA 01 3630000
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[chemical_name] =>
[weight] => 449.84
[form] => C20H18ClF2N5O3
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Catalogue No.:PA 01 3630000
Molecular Formula : C20H18ClF2N5O3
Molecular Weight : 449.84
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[catalogue_number] => PA 01 3631000
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[chemical_name] =>
[weight] => 478.84
[form] => C20H17ClF2N6O4
[cas] => NA
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(R)-N-(4-(Chlorodifluoromethoxy)phenyl)-6-(3-hydroxypyrrolidin-1-yl)-N-nitroso-5-(1H-pyrazol-3-yl)nicotinamide
Catalogue No.:PA 01 3631000
Molecular Formula : C20H17ClF2N6O4
Molecular Weight : 478.84
stdClass Object
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[pname] => Deschloro Asciminib Impurity
[catalogue_number] => PA 01 3631001
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[chemical_name] =>
[weight] => 415.4
[form] => C20H19F2N5O3
[cas] => 3033653-93-6
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Deschloro Asciminib Impurity
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[pname] => (R)-6-(3-Hydroxypyrrolidin-1-yl)-5-(1H-pyrazol-3-yl)-N-(4-(trifluoromethoxy)phenyl)nicotinamide
[catalogue_number] => PA 01 3631002
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[chemical_name] =>
[weight] => 433.39
[form] => C20H18F3N5O3
[cas] => 1492952-55-2
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(R)-6-(3-Hydroxypyrrolidin-1-yl)-5-(1H-pyrazol-3-yl)-N-(4-(trifluoromethoxy)phenyl)nicotinamide
Catalogue No.:PA 01 3631002
Molecular Formula : C20H18F3N5O3
Molecular Weight : 433.39
stdClass Object
(
[pname] => Asciminib S-Isomer
[catalogue_number] => PA 01 3631003
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[chemical_name] =>
[weight] => 449.84
[form] => C20H18ClF2N5O3
[cas] => 1492952-73-4
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Catalogue No.:PA 01 3631003
Molecular Formula : C20H18ClF2N5O3
Molecular Weight : 449.84
stdClass Object
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[pname] => N-(4-(Chlorodifluoromethoxy)phenyl)-6-(3-oxopyrrolidin-1-yl)-5-(1H-pyrazol-5-yl)nicotinamide
[catalogue_number] => PA 01 3631004
[category_ids] => ,76,78,70,82,
[chemical_name] =>
[weight] => 447.83
[form] => C20H16ClF2N5O3
[cas] => NA
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N-(4-(Chlorodifluoromethoxy)phenyl)-6-(3-oxopyrrolidin-1-yl)-5-(1H-pyrazol-5-yl)nicotinamide
Catalogue No.:PA 01 3631004
Molecular Formula : C20H16ClF2N5O3
Molecular Weight : 447.83
