everolimus and its Impurities

Everolimus is currently used as an immunosuppressant to prevent rejection of organ transplants. It is a derivative of Rapamycin, and works similarly to Rapamycin as an mTOR inhibitor. Reference standards of Everolimus API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below

Displaying 39 results for everolimus Impurities
PA 05 73000

Everolimus

Everolimus

  • Catalogue No.:PA 05 73000

  • CAS :

    159351-69-6

  • Molecular Formula : C53H83NO14

  • Molecular Weight : 958.22

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PA 05 73510

Everolimus Isomer C

Everolimus Isomer C

  • Catalogue No.:PA 05 73510

  • CAS :

    908340-97-6

  • Molecular Formula : C53H83NO14

  • Molecular Weight : 958.22

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PA 05 73520

42-O-tert-Butyldimethylsilyloxyethyl Rapamycin

42-O-tert-Butyldimethylsilyloxyethyl Rapamycin

  • Catalogue No.:PA 05 73520

  • CAS :

    159351-68-5

  • Molecular Formula : C59H97NO14Si

  • Molecular Weight : 1072.49

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PA 05 73530

2-((tert-Butyldimethylsilyl)oxy)ethyl 2,2,2-trichloroacetimidate

2-((tert-Butyldimethylsilyl)oxy)ethyl 2,2,2-trichloroacetimidate

  • Catalogue No.:PA 05 73530

  • CAS :

    NA

  • Molecular Formula : C10H20Cl3NO2Si

  • Molecular Weight : 320.72

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PA 05 73540

Desmethyl Everolimus

Desmethyl Everolimus

  • Catalogue No.:PA 05 73540

  • CAS :

    745779-75-3

  • Molecular Formula : C52H81NO14

  • Molecular Weight : 944.2

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PA 05 73550

(2S)-1-[[(2R,3R,6S)-6-[(2S,3E,5E,7E,9S,11R)-2,13-Dimethoxy-3,9,11-trimethyl-12-oxo-3,5,7-tridecatrienyl]tetrahydro-2-hydroxy-3-methyl-2H-pyran-2-yl]oxoacetyl]-2-piperidinecarboxylic Acid

(2S)-1-[[(2R,3R,6S)-6-[(2S,3E,5E,7E,9S,11R)-2,13-Dimethoxy-3,9,11-trimethyl-12-oxo-3,5,7-tridecatrienyl]tetrahydro-2-hydroxy-3-methyl-2H-pyran-2-yl]oxoacetyl]-2-piperidinecarboxylic Acid

  • Catalogue No.:PA 05 73550

  • CAS :

    147438-30-0

  • Molecular Formula : C32H49NO9

  • Molecular Weight : 591.73

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PA 05 73560

Seco Everolimus B

Seco Everolimus B

  • Catalogue No.:PA 05 73560

  • CAS :

    769905-89-7

  • Molecular Formula : C53H85NO15

  • Molecular Weight : 976.24

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PA 05 73570

1-(2-((2R,3R,6S)-2-Hydroxy-6-((2S,3E,5E,7E,9S,11R,14R,15E,17R,19E,21R)-14-hydroxy-22-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-2,13-dimethoxy-3,9,11,15,17,21-hexamethyl-12,18-dioxodocosa-3,5,7,15,19-pentaen-1-yl)-3-methyltetrahydro-2H-pyran-2-yl)-2-oxoacetyl)piperidine-2-carboxylic Acid

1-(2-((2R,3R,6S)-2-Hydroxy-6-((2S,3E,5E,7E,9S,11R,14R,15E,17R,19E,21R)-14-hydroxy-22-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-2,13-dimethoxy-3,9,11,15,17,21-hexamethyl-12,18-dioxodocosa-3,5,7,15,19-pentaen-1-yl)-3-methyltetrahydro-2H-pyran-2-yl)-2-oxoacetyl)piperidine-2-carboxylic Acid

  • Catalogue No.:PA 05 73570

  • CAS :

    NA

  • Molecular Formula : C53H83NO14

  • Molecular Weight : 958.22

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PA 05 73580

(S)-(2R,3S,6R,E)-1-((1S,3R,4R)-4-(2-Hydroxyethoxy)-3-methoxycyclohexyl)-2,6,8-trimethyl-5,9-dioxonon-7-en-3-yl 1-(2-((2R,3R,6S)-6-((2S,3E,5E,7E,9S,11R)-2,13-dimethoxy-3,9,11-trimethyl-12-oxotrideca-3,5,7-trien-1-yl)-2-hydroxy-3-methyltetrahydro-2H-pyran-2-yl)-2-oxoacetyl)piperidine-2-carboxylate

(S)-(2R,3S,6R,E)-1-((1S,3R,4R)-4-(2-Hydroxyethoxy)-3-methoxycyclohexyl)-2,6,8-trimethyl-5,9-dioxonon-7-en-3-yl 1-(2-((2R,3R,6S)-6-((2S,3E,5E,7E,9S,11R)-2,13-dimethoxy-3,9,11-trimethyl-12-oxotrideca-3,5,7-trien-1-yl)-2-hydroxy-3-methyltetrahydro-2H-pyran-2-yl)-2-oxoacetyl)piperidine-2-carboxylate

  • Catalogue No.:PA 05 73580

  • CAS :

    1708118-13-1

  • Molecular Formula : C53H83NO14

  • Molecular Weight : 958.22

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PA 05 73590

1-(2-((2R,6S)-2-Hydroxy-6-((2R,3E,5E,7E,9R,11S,14R,15E,17S,19E,22R)-14-hydroxy-22-((1S,3R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-2,13-dimethoxy-3,9,11,15,17,21-hexamethyl-12,18-dioxotricosa-3,5,7,15,19-pentaen-1-yl)tetrahydro-2H-pyran-2-yl)-2-oxoacetyl)piperidine-2-carboxylic Acid

1-(2-((2R,6S)-2-Hydroxy-6-((2R,3E,5E,7E,9R,11S,14R,15E,17S,19E,22R)-14-hydroxy-22-((1S,3R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-2,13-dimethoxy-3,9,11,15,17,21-hexamethyl-12,18-dioxotricosa-3,5,7,15,19-pentaen-1-yl)tetrahydro-2H-pyran-2-yl)-2-oxoacetyl)piperidine-2-carboxylic Acid

  • Catalogue No.:PA 05 73590

  • CAS :

    NA

  • Molecular Formula : C53H83NO14

  • Molecular Weight : 958.22

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PA 05 73600

Everolimus 28-Ethylhydroxy Impurity

Everolimus 28-Ethylhydroxy Impurity

  • Catalogue No.:PA 05 73600

  • CAS :

    NA

  • Molecular Formula : C53H83NO14

  • Molecular Weight : 958.22

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PA 05 73620

Everolimus Cyclic Hemiacetal

Everolimus Cyclic Hemiacetal

  • Catalogue No.:PA 05 73620

  • CAS :

    NA

  • Molecular Formula : C55H89NO16

  • Molecular Weight : 1020.31

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PA 05 73630

(1R,9S,12S,15S,16E,18R,19R,21R,23S,24Z,26E,28E,30S,35R)-1-18-Dihydroxy-12{(1R)-2-[1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]-1-methylethyl}-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.04.9]-hexatriaconta-16,24,26,28,-tetraene-2,3,10,14,20-pentanone

(1R,9S,12S,15S,16E,18R,19R,21R,23S,24Z,26E,28E,30S,35R)-1-18-Dihydroxy-12{(1R)-2-[1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]-1-methylethyl}-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.04.9]-hexatriaconta-16,24,26,28,-tetraene-2,3,10,14,20-pentanone

  • Catalogue No.:PA 05 73630

  • CAS :

    NA

  • Molecular Formula : C53H83NO14

  • Molecular Weight : 958.22

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PA 05 73640

(1R,9S,12S,15S,16E,18R,19R,21R,23S,24E,26E,28E,30S,35R)-1-Hydroxy-12{(1R)-2-[1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]-1-methylethyl}-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.04.9]-hexatriaconta-16,24,26,28,-tetraene-2,3,10,14,18,20-Hexanone

(1R,9S,12S,15S,16E,18R,19R,21R,23S,24E,26E,28E,30S,35R)-1-Hydroxy-12{(1R)-2-[1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]-1-methylethyl}-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.04.9]-hexatriaconta-16,24,26,28,-tetraene-2,3,10,14,18,20-Hexanone

  • Catalogue No.:PA 05 73640

  • CAS :

    NA

  • Molecular Formula : C53H81NO14

  • Molecular Weight : 956.21

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PA 05 73650

Everolimus O-Ethyl Impurity

Everolimus O-Ethyl Impurity

  • Catalogue No.:PA 05 73650

  • CAS :

    1704711-12-5

  • Molecular Formula : C54H85NO14

  • Molecular Weight : 972.25

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PA 05 73660

Everolimus - Impurity B

(2S)-1-[[(2R,3R,6S)-2-Hydroxy-6-[(2S,3E,5E,7E,9S,11R,13R,14R,15E,17R,19E,21R)-14- hydroxy-22-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]-2,13-dimethoxy-3,9, 11,15,17,21-hexamethyl-12,18-dioxodocosa-3,5,7,15,19-pentaen-1-yl]-3-methyloxan-2- yl](oxo)acetyl]piperidine-2-carboxylic Acid

  • Catalogue No.:PA 05 73660

  • CAS :

    1062122-63-7

  • Molecular Formula : C53H83NO14

  • Molecular Weight : 958.22

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PA 05 73670

42-O-Formyl Rapamycin

42-O-Formyl Rapamycin

  • Catalogue No.:PA 05 73670

  • CAS :

    1237826-25-3

  • Molecular Formula : C52H79NO14

  • Molecular Weight : 942.18

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PA 05 73680

Everolimus 27-O-Desmethyl

Everolimus 27-O-Desmethyl

  • Catalogue No.:PA 05 73680

  • CAS :

    NA

  • Molecular Formula : C52H81NO14

  • Molecular Weight : 944.2

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PA STI 040450

Everolimus-d4

Everolimus-d4

  • Catalogue No.:PA STI 040450

  • CAS :

    1338452-54-2

  • Molecular Formula : C53H79D4NO14

  • Molecular Weight : 962.25

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PA STI 040451

Everolimus-13C2,D4

Everolimus-13C2,D4

  • Catalogue No.:PA STI 040451

  • CAS :

    1661009-29-5

  • Molecular Formula : C5113C2H79D4NO14

  • Molecular Weight : 964.23

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PA 05 73020

(S)-1-(2-((2R,3R,6S)-2-Hydroxy-6-((2S,3E,5E,7E,9S,11R,13R,14R,15E,17R,19Z,21R)-14-hydroxy-22-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-2,13-dimethoxy-3,9,11,15,17,21-hexamethyl-12,18-dioxodocosa-3,5,7,15,19-pentaen-1-yl)-3-methyltetrahydro-2H-pyran-2-yl)-2-oxoacetyl)piperidine-2-carboxylic Acid

(2S)-1-[[(2R,3R,6S)-2-Hydroxy-6-[(2S,3E,5E,7E,9S,11R,13R,14R,15E,17R,19Z,21R)-14-hydroxy-22-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]-2,13-dimethoxy-3,9,11,15,17,21-hexamethyl-12,18-dioxodocosa-3,5,7,15,19-pentaen-1-yl]-3-methyltetrahydro-2H-pyran-2-yl](oxo)acetyl]piperidine-2-carboxylic Acid

  • Catalogue No.:PA 05 73020

  • CAS :

    763911-41-7

  • Molecular Formula : C53H83NO14

  • Molecular Weight : 958.24

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PA 05 73030

Everolimus - Impurity C

19-O-Demethyl Everolimus

  • Catalogue No.:PA 05 73030

  • CAS :

    NA

  • Molecular Formula : C52H81NO14

  • Molecular Weight : 944.21

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PA 05 73040

Everolimus - Impurity D

18-O-Hydroxyethyl sirolimus

  • Catalogue No.:PA 05 73040

  • CAS :

    2760174-96-5

  • Molecular Formula : C53H83NO14

  • Molecular Weight : 958.24

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PA 05 73060

Everolimus - Impurity F

Everolimus Cyclic Hemiacetal

  • Catalogue No.:PA 05 73060

  • CAS :

    NA

  • Molecular Formula : C55H89NO16

  • Molecular Weight : 1020.31

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PA 05 0731000

2,6-di-tert-Butyl-4-methylenecyclohexa-2,5-dien-1-one

2,6-di-tert-Butyl-4-methylenecyclohexa-2,5-dien-1-one

  • Catalogue No.:PA 05 0731000

  • CAS :

    2607-52-5

  • Molecular Formula : C15H22O

  • Molecular Weight : 218.34

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PA 05 0730050

Everolimus - Impurity E

Formyl Sirolimus

  • Catalogue No.:PA 05 0730050

  • CAS :

    1237826-25-3

  • Molecular Formula : C52H79NO14

  • Molecular Weight : 942.2

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PA 05 0731001

Everolimus System Suitability Mixture

Everolimus System Suitability Mixture

  • Catalogue No.:PA 05 0731001

  • CAS :

    NA

  • Molecular Formula : C42H54N6O6

  • Molecular Weight : 738.93

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PA 05 0731002

1-(2-((2R,3R,6S)-6-((2S,3E,5E,7E,9S,11R)-2,13-Dimethoxy-3,9,11-trimethyl-12-oxotrideca-3,5,7-trien-1-yl)-2-hydroxy-3-methyltetrahydro-2H-pyran-2-yl)-2-oxoacetyl)piperidine-2-carboxylic acid;

1-(2-((2R,3R,6S)-6-((2S,3E,5E,7E,9S,11R)-2,13-Dimethoxy-3,9,11-trimethyl-12-oxotrideca-3,5,7-trien-1-yl)-2-hydroxy-3-methyltetrahydro-2H-pyran-2-yl)-2-oxoacetyl)piperidine-2-carboxylic acid;

  • Catalogue No.:PA 05 0731002

  • CAS :

    NA

  • Molecular Formula : C32H49NO9

  • Molecular Weight : 591.74

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PAI 05 073001

2-((Tert-butyldimethylsilyl)oxy)ethyl trifluoromethanesulfonate

2-((Tert-butyldimethylsilyl)oxy)ethyl trifluoromethanesulfonate

  • Catalogue No.:PAI 05 073001

  • CAS :

    164162-36-1

  • Molecular Formula : C9H19F3O4SSi

  • Molecular Weight : 308.39

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PA 05 0731003

Prolyl Everolimus

Prolyl Everolimus

  • Catalogue No.:PA 05 0731003

  • CAS :

    NA

  • Molecular Formula : C52H81NO14

  • Molecular Weight : 944.21

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PA EPY0002048

Everolimus (Y0002048)

Everolimus (Y0002048)

  • Catalogue No.:PA EPY0002048

  • CAS :

    159351-69-6

  • Molecular Formula : NA

  • Molecular Weight : NA

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PA 05 0731004

Rapamycin, 7-O-demethyl-42-O-(2-hydroxyethyl)-, (7ξ)-

Rapamycin, 7-O-demethyl-42-O-(2-hydroxyethyl)-, (7ξ)-

  • Catalogue No.:PA 05 0731004

  • CAS :

    408496-50-4

  • Molecular Formula : C52H81NO14

  • Molecular Weight : 944.21

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PA 05 0731005

16-Demethoxy-16(R)-ethoxyeverolimus

16-Demethoxy-16(R)-ethoxyeverolimus

  • Catalogue No.:PA 05 0731005

  • CAS :

    NA

  • Molecular Formula : C54H85NO14

  • Molecular Weight : 972.27

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PA 05 0731006

(3S,6R,7E,9R,10R,12R,14R,16E,18E,20E,23S,26R,27R,34aS)-15-Ethoxy-9,27-dihydroxy-3-((R)-1-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)propan-2-yl)-10-methoxy-6,8,12,14,20,26-hexamethyl-9,10,12,13,14,15,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-3H-23,27-epoxypyrido[2,1-c][1]oxa[4]azacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentaone

(3S,6R,7E,9R,10R,12R,14R,16E,18E,20E,23S,26R,27R,34aS)-15-Ethoxy-9,27-dihydroxy-3-((R)-1-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)propan-2-yl)-10-methoxy-6,8,12,14,20,26-hexamethyl-9,10,12,13,14,15,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-3H-23,27-epoxypyrido[2,1-c][1]oxa[4]azacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentaone

  • Catalogue No.:PA 05 0731006

  • CAS :

    NA

  • Molecular Formula : C54H85NO14

  • Molecular Weight : 972.27

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PA 05 0731007

Everolimus Impurity 1

Everolimus Impurity 1

  • Catalogue No.:PA 05 0731007

  • CAS :

    NA

  • Molecular Formula : C53H83NO15

  • Molecular Weight : 974.24

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PA 05 0731008

(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,21,27-Trihydroxy-3-((R)-1-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)propan-2-yl)-10-methoxy-6,8,12,14,20,26-hexamethyl-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-3H-23,27-epoxypyrido[2,1-c][1]oxa[4]azacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentaone

(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,21,27-Trihydroxy-3-((R)-1-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)propan-2-yl)-10-methoxy-6,8,12,14,20,26-hexamethyl-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-3H-23,27-epoxypyrido[2,1-c][1]oxa[4]azacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentaone

  • Catalogue No.:PA 05 0731008

  • CAS :

    NA

  • Molecular Formula : C52H81NO14

  • Molecular Weight : 944.21

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PA 05 0731009

(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-21-Ethoxy-9,27-dihydroxy-3-((R)-1-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)propan-2-yl)-10-methoxy-6,8,12,14,20,26-hexamethyl-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-3H-23,27-epoxypyrido[2,1-c][1]oxa[4]azacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentaone

(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-21-Ethoxy-9,27-dihydroxy-3-((R)-1-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)propan-2-yl)-10-methoxy-6,8,12,14,20,26-hexamethyl-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-3H-23,27-epoxypyrido[2,1-c][1]oxa[4]azacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentaone

  • Catalogue No.:PA 05 0731009

  • CAS :

    NA

  • Molecular Formula : C54H85NO14

  • Molecular Weight : 972.27

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PA 05 0731010

(2R,3S,E)-1-((1S,3R,4R)-4-(2-Hydroxyethoxy)-3-methoxycyclohexyl)-2,6,8-trimethyl-5,9-dioxonon-7-en-3-yl (2S)-1-(2-((2R,3R)-6-((2S,3E,5E,7E,9S,11R)-2,13-dimethoxy-3,9,11-trimethyl-12-oxotrideca-3,5,7-trien-1-yl)-2-hydroxy-3-methyltetrahydro-2H-pyran-2-yl)-2-oxoacetyl)piperidine-2-carboxylate

(2R,3S,E)-1-((1S,3R,4R)-4-(2-Hydroxyethoxy)-3-methoxycyclohexyl)-2,6,8-trimethyl-5,9-dioxonon-7-en-3-yl (2S)-1-(2-((2R,3R)-6-((2S,3E,5E,7E,9S,11R)-2,13-dimethoxy-3,9,11-trimethyl-12-oxotrideca-3,5,7-trien-1-yl)-2-hydroxy-3-methyltetrahydro-2H-pyran-2-yl)-2-oxoacetyl)piperidine-2-carboxylate

  • Catalogue No.:PA 05 0731010

  • CAS :

    NA

  • Molecular Formula : C53H83NO14

  • Molecular Weight : 958.24

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PA 05 0731011

(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,23S,26R,27R,34aS)-15-Ethoxy-9,27-dihydroxy-3-((R)-1-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)propan-2-yl)-10-methoxy-6,8,12,14,20,26-hexamethyl-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-3H-23,27-epoxypyrido[2,1-c][1]oxa[4]azacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentaone

(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,23S,26R,27R,34aS)-15-Ethoxy-9,27-dihydroxy-3-((R)-1-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)propan-2-yl)-10-methoxy-6,8,12,14,20,26-hexamethyl-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-3H-23,27-epoxypyrido[2,1-c][1]oxa[4]azacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentaone

  • Catalogue No.:PA 05 0731011

  • CAS :

    NA

  • Molecular Formula : C54H85NO14

  • Molecular Weight : 972.27

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