polymyxin b and its Impurities
An antibacterial drug which is derived from bacterium Bacillus polymyxa. It is used for resistant Gram-negative infections. Exhibits bactericidal properties.Reference standards of Polymyxin B API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.


(4S)-N-((2S,3R)-1-(((S)-4-Amino-1-oxo-1-(((3S,6S,9S,12S,15S,18S,21S)-6,9,18-tris(2-aminoethyl)-15-benzyl-3-((R)-1-hydroxyethyl)-12-isobutyl-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptaazacyclotricosan-21-yl)amino)butan-2-yl)amino)-3-hydroxy-1-oxobutan-2-yl)-2-(5-methylheptyl)-3,4,5,6-tetrahydropyrimidine-4-carboxamide
(4S)-N-((2S,3R)-1-(((S)-4-Amino-1-oxo-1-(((3S,6S,9S,12S,15S,18S,21S)-6,9,18-tris(2-aminoethyl)-15-benzyl-3-((R)-1-hydroxyethyl)-12-isobutyl-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptaazacyclotricosan-21-yl)amino)butan-2-yl)amino)-3-hydroxy-1-oxobutan-2-yl)-2-(5-methylheptyl)-3,4,5,6-tetrahydropyrimidine-4-carboxamide
Catalogue No.:PA PEP 001220
CAS :
NA
Molecular Formula : C56H96N16O12
Molecular Weight : 1185.48


N-(4-Amino-1-((1-((4-amino-1-oxo-1-((6,9,18-tris(2-aminoethyl)-15-benzyl-3-(1-hydroxyethyl)-12-isopropyl-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptaazacyclotricosan-21-yl)amino)butan-2-yl)amino)-3-hydroxy-1-oxobutan-2-yl)amino)-1-oxobutan-2-yl)-6-methyloctanamide
N-(4-Amino-1-((1-((4-amino-1-oxo-1-((6,9,18-tris(2-aminoethyl)-15-benzyl-3-(1-hydroxyethyl)-12-isopropyl-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptaazacyclotricosan-21-yl)amino)butan-2-yl)amino)-3-hydroxy-1-oxobutan-2-yl)amino)-1-oxobutan-2-yl)-6-methyloctanamide
Catalogue No.:PA PEP 003131
CAS :
NA
Molecular Formula : C55H96N16O13
Molecular Weight : 1189.47


N-(4-Amino-1-((1-((4-amino-1-oxo-1-((6,9,18-tris(2-aminoethyl)-3-(1-hydroxyethyl)-12,15-diisobutyl-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptaazacyclotricosan-21-yl)amino)butan-2-yl)amino)-3-hydroxy-1-oxobutan-2-yl)amino)-1-oxobutan-2-yl)-6-methyloctanamide
N-(4-Amino-1-((1-((4-amino-1-oxo-1-((6,9,18-tris(2-aminoethyl)-3-(1-hydroxyethyl)-12,15-diisobutyl-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptaazacyclotricosan-21-yl)amino)butan-2-yl)amino)-3-hydroxy-1-oxobutan-2-yl)amino)-1-oxobutan-2-yl)-6-methyloctanamide
Catalogue No.:PA PEP 003132
CAS :
NA
Molecular Formula : C53H100N16O13
Molecular Weight : 1169.48


N-(4-Amino-1-((1-((4-amino-1-oxo-1-((6,9,18-tris(2-aminoethyl)-15-benzyl-3-(1-hydroxyethyl)-12-isobutyl-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptaazacyclotricosan-21-yl)amino)butan-2-yl)amino)-3-hydroxy-1-oxopropan-2-yl)amino)-1-oxobutan-2-yl)-6-methyloctanamide
N-(4-Amino-1-((1-((4-amino-1-oxo-1-((6,9,18-tris(2-aminoethyl)-15-benzyl-3-(1-hydroxyethyl)-12-isobutyl-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptaazacyclotricosan-21-yl)amino)butan-2-yl)amino)-3-hydroxy-1-oxopropan-2-yl)amino)-1-oxobutan-2-yl)-6-methyloctanamide
Catalogue No.:PA PEP 003133
CAS :
NA
Molecular Formula : C55H96N16O13
Molecular Weight : 1189.47


N-(4-Amino-1-oxo-1-((4,7,16,22-tetrakis(2-aminoethyl)-13-benzyl-10-isobutyl-26,28-dimethyl-3,6,9,12,15,18,21,24,29-nonaoxo-27-oxa-2,5,8,11,14,17,20,23,30-nonaazabicyclo[17.9.4]dotriacontan-25-yl)amino)butan-2-yl)-6-methyloctanamide
N-(4-Amino-1-oxo-1-((4,7,16,22-tetrakis(2-aminoethyl)-13-benzyl-10-isobutyl-26,28-dimethyl-3,6,9,12,15,18,21,24,29-nonaoxo-27-oxa-2,5,8,11,14,17,20,23,30-nonaazabicyclo[17.9.4]dotriacontan-25-yl)amino)butan-2-yl)-6-methyloctanamide
Catalogue No.:PA PEP 003135
CAS :
NA
Molecular Formula : C56H96N16O12
Molecular Weight : 1185.48


N-(4-Amino-1-((1-((4-amino-1-oxo-1-((6,9,18-tris(2-aminoethyl)-15-benzyl-3-(hydroxymethyl)-12-isobutyl-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptaazacyclotricosan-21-yl)amino)butan-2-yl)amino)-3-hydroxy-1-oxobutan-2-yl)amino)-1-oxobutan-2-yl)-6-methyloctanamide
N-(4-Amino-1-((1-((4-amino-1-oxo-1-((6,9,18-tris(2-aminoethyl)-15-benzyl-3-(hydroxymethyl)-12-isobutyl-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptaazacyclotricosan-21-yl)amino)butan-2-yl)amino)-3-hydroxy-1-oxobutan-2-yl)amino)-1-oxobutan-2-yl)-6-methyloctanamide
Catalogue No.:PA PEP 003136
CAS :
NA
Molecular Formula : C55H96N16O13
Molecular Weight : 1189.47


N-(4-Amino-1-((1-((4-amino-1-oxo-1-((6,9,18-tris(2-aminoethyl)-15-benzyl-3-(1-hydroxyethyl)-12-isobutyl-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptaazacyclotricosan-21-yl)amino)butan-2-yl)amino)-3-hydroxy-1-oxobutan-2-yl)amino)-1-oxobutan-2-yl)-7-methyloctanamide
N-(4-Amino-1-((1-((4-amino-1-oxo-1-((6,9,18-tris(2-aminoethyl)-15-benzyl-3-(1-hydroxyethyl)-12-isobutyl-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptaazacyclotricosan-21-yl)amino)butan-2-yl)amino)-3-hydroxy-1-oxobutan-2-yl)amino)-1-oxobutan-2-yl)-7-methyloctanamide
Catalogue No.:PA PEP 003137
CAS :
NA
Molecular Formula : C56H98N16O13
Molecular Weight : 1203.5