sacubitril and its Impurities

An antihypertensive drug, Sacubitril is used in combination with valsartan for the treatment of heart ailments. A prodrug of sacubitrilat which is an inhibitor of enzyme neprilysin, which aids the degradation of blood pressure-lowering peptides, atrial and brain natriuretic peptide.Reference standards of Sacubitril API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

Displaying 10 results for sacubitril Impurities
PA 19 0661075

3-(((2S,4R)-1-([1,1'-Biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-3-oxopropanoic Acid

3-(((2S,4R)-1-([1,1'-Biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-3-oxopropanoic Acid

  • Catalogue No.:PA 19 0661075

  • CAS :

    1027303-80-5

  • Molecular Formula : C23H27NO5

  • Molecular Weight : 397.47

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PA 19 0661076

Calcium 4-(((2S,4R)-1-([1,1'-biphenyl]-4-yl)-5-isopropoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoate

Calcium 4-(((2S,4R)-1-([1,1'-biphenyl]-4-yl)-5-isopropoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoate

  • Catalogue No.:PA 19 0661076

  • CAS :

    2984580-05-2

  • Molecular Formula : C50H60CaN2O10

  • Molecular Weight : 889.11

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PA 19 0661077

rel-4-((3R,5S)-5-([1,1'-Biphenyl]-4-ylmethyl)-3-methyl-2-oxopyrrolidin-1-yl)-4-oxobutanoic Acid

rel-4-((3R,5S)-5-([1,1'-Biphenyl]-4-ylmethyl)-3-methyl-2-oxopyrrolidin-1-yl)-4-oxobutanoic Acid

  • Catalogue No.:PA 19 0661077

  • CAS :

    2216746-87-9

  • Molecular Formula : C22H23NO4

  • Molecular Weight : 365.43

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PA 19 0661078

Ethyl (2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-(4-ethoxy-4-oxobutanamido)-2-methylpentanoate

Ethyl (2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-(4-ethoxy-4-oxobutanamido)-2-methylpentanoate

  • Catalogue No.:PA 19 0661078

  • CAS :

    2376611-98-0

  • Molecular Formula : C26H33NO5

  • Molecular Weight : 439.55

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PA 19 0661079

Cyclohexane, (2-bromoethoxy)

Cyclohexane, (2-bromoethoxy)

  • Catalogue No.:PA 19 0661079

  • CAS :

    131665-94-6

  • Molecular Formula : C8H15BrO

  • Molecular Weight : 207.11

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PA 19 0661080

(R)-2-Amino-3-(4-iodophenyl)propan-1-ol

(R)-2-Amino-3-(4-iodophenyl)propan-1-ol

  • Catalogue No.:PA 19 0661080

  • CAS :

    210554-97-5

  • Molecular Formula : C9H12INO

  • Molecular Weight : 277.11

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PA 19 0661081

tert-Butyl (R)-(1-hydroxy-3-(4-iodophenyl)propan-2-yl)carbamate

tert-Butyl (R)-(1-hydroxy-3-(4-iodophenyl)propan-2-yl)carbamate

  • Catalogue No.:PA 19 0661081

  • CAS :

    210962-92-8

  • Molecular Formula : C14H20INO3

  • Molecular Weight : 377.22

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PA 19 0661082

5-(((2S,4R)-1-([1,1'-Biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-5-oxopentanoic Acid

5-(((2S,4R)-1-([1,1'-Biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-5-oxopentanoic Acid

  • Catalogue No.:PA 19 0661082

  • CAS :

    773820-89-6

  • Molecular Formula : C25H31NO5

  • Molecular Weight : 425.53

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PA 19 0661083

Methyl 4-([1,1'-biphenyl]-4-yl)-3-oxobutanoate

Methyl 4-([1,1'-biphenyl]-4-yl)-3-oxobutanoate

  • Catalogue No.:PA 19 0661083

  • CAS :

    100160-75-6

  • Molecular Formula : C17H16O3

  • Molecular Weight : 268.31

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PA 19 0661084

5-([1,1'-Biphenyl]-4-yl)-2-methylene-4-oxopentanoic Acid

5-([1,1'-Biphenyl]-4-yl)-2-methylene-4-oxopentanoic Acid

  • Catalogue No.:PA 19 0661084

  • CAS :

    2454675-99-9

  • Molecular Formula : C18H16O3

  • Molecular Weight : 280.32

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CPHI INDIA- 28, 30 November