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Catalogue number: PA 73 50000
Chemical name: Triciribine

CAS Number:

35943-35-2

Category: impurities,metabolites,pharmaceutical standards,intermediates,Fine Chemicals
Synonyms:

1,5-Dihydro-5-methyl-1-ß-D-ribofuranosyl-1,4,5,6,8-pentaazaacenaphthylen-3-amine; 6-Amino-4-methyl-8-(β-D-ribofuranosyl)-4H,8H-pyrrolo[4,3,2-de]pyrimido[4,5-c]pyridazine;

Molecular form: C13H16N6O4
Appearance: Off-White to Pale Yellow Solid
Mol. Weight: 320.3
Storage: 2-8°C Refrigerator
Shipping Conditions: Ambient
Applications: Triciribine is an antitumor tricyclic nucleoside. Triciribine acts as a potent, small-molecule inhibitor of AKT phosphorylation in subjects with solid tumors contining activated AKT. Triciribine is also a selective inhibitor of HIV-1 and HIV-2, including strains known to be resistant to AZT or TIBO.

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