| Catalogue number: | PA STI 004300 |
| Chemical name: | Aflatoxin B1-13C,d3 |
CAS Number: |
NA |
| Category: | heterocycles,metabolites,impurities,pharmaceutical standards,intermediates,Fine Chemicals,stable isotopes |
| Synonyms: | (-)-Aflatoxin B1-13C,d3; AFB1-d3; (6aR,9aS)-4-(Methoxy-13C-d3)-2,3,6a,9a-tetrahydrocyclopenta[c]furo[3',2':4,5]furo[2,3-h]chromene-1,11-dione; |
| Molecular form: | C1613CH9D3O6 |
| Appearance: | NA |
| Mol. Weight: | 316.28 |
| Storage: | 2-8°C Refrigerator |
| Shipping Conditions: | Ambient |
| Applications: | Aflatoxin B1 labelled standard. Aflatoxins B1, B2, G1, G2 as secondary metabolites of fungal species such as Aspergillus flavus or Aspergillus parasiticus growing on a variety of foods (peanuts, nuts, spices, cereals). Aflatoxins are a group of very carcinogenic mycotoxins with hepatotoxic effects. Aflatoxin is biotransformed to genotoxic intermediates by P450 Phase I enzymes, mainly CYP3A4 via aflatoxin B1 3-hydroxylation. Detoxification depends on Phase II enzymes, such as Glutathione S-Transferase and AFB(1)-aldehyde reductase (AFAR). Aflatoxin B1 is one of the most potent environmental mutagens and carcinogens known. |
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