calicheamicin and its Impurities

Calicheamicin is a very potent anti-tumor antibiotic and the only enediyne compound presently used commercially as an anticancer agent. It is a class of enediyne antitumor antibiotics derived from the bacterium Micromonospora echinospora, with calicheamicin γ1 being the most notable.. Reference standards of Calicheamicin API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below