mertansine
Mertansine is a thiol-containing maytansinoid which is used for therapeutic purposes is attached to a monoclonal antibody through reaction of the thiol group with a linker structure to create an antibody-drug conjugate. It is also called DM1. Reference standards of Mertansine API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
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[pname] => Mertansine
[catalogue_number] => PA 40 42000
[category_ids] => ,88,82,80,79,78,71,70,170,
[chemical_name] =>
[weight] => 738.29
[form] => C35H48ClN3O10S
[cas] => 139504-50-0
[pslug] => 139504-50-0-mertansine-api-pa4042000
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Catalogue No.:PA 40 42000
Molecular Formula : C35H48ClN3O10S
Molecular Weight : 738.29
stdClass Object
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[pname] => 2,5-Dioxopyrrolidin-1-yl 4-((3-((3-(((2S)-1-(((14S,16S,33S,2R,4R,10E,12Z,14R)-86-chloro-14-hydroxy-85,14-dimethoxy-33,2,7,10-tetramethyl-12,6-dioxo-7-aza-1(6,4)-oxazinana-3(2,3)-oxirana-8(1,3)-benzenacyclotetradecaphane-10,12-dien-4-yl)oxy)-1-oxopropan-2-yl)(methyl)amino)-3-oxopropyl)thio)-2,5-dioxopyrrolidin-1-yl)methyl)cyclohexane-1-carboxylate
[catalogue_number] => PA 40 42510
[category_ids] => ,82,80,78,75,70,170,
[chemical_name] =>
[weight] => 1072.61
[form] => C51H66ClN5O16S
[cas] => 1228105-51-8
[pslug] => 1228105-51-8-2-5-dioxopyrrolidin-1-yl-4-3-3-2s-1-14s-16s-33s-2r-4r-10e-12z-14r-86-chloro-14-hydroxy-85-14-dimethoxy-33-2-7-10-tetramethyl-12-6-dioxo-7-aza-1-6-4-oxazinana-3-2-3-oxirana-8-1-3-benzenacyclotetradecaphane-10-12-dien-4-yl-oxy-1-oxopropan-2-yl-methyl-amino-3-oxopropyl-thio-2-5-dioxopyrrolidin-1-yl-methyl-cyclohexane-1-carboxylate-pa4042510
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2,5-Dioxopyrrolidin-1-yl 4-((3-((3-(((2S)-1-(((14S,16S,33S,2R,4R,10E,12Z,14R)-86-chloro-14-hydroxy-85,14-dimethoxy-33,2,7,10-tetramethyl-12,6-dioxo-7-aza-1(6,4)-oxazinana-3(2,3)-oxirana-8(1,3)-benzenacyclotetradecaphane-10,12-dien-4-yl)oxy)-1-oxopropan-2-yl)(methyl)amino)-3-oxopropyl)thio)-2,5-dioxopyrrolidin-1-yl)methyl)cyclohexane-1-carboxylate
Catalogue No.:PA 40 42510
Molecular Formula : C51H66ClN5O16S
Molecular Weight : 1072.61
stdClass Object
(
[pname] => Maytansine, N2′-deacetyl-N2′-(3-mercapto-1-oxopropyl)-, (2′R)
[catalogue_number] => PA 40 0421000
[category_ids] => ,78,70,82,88,
[chemical_name] =>
[weight] => 738.29
[form] => C35H48ClN3O10S
[cas] => 936481-22-0
[pslug] => 936481-22-0-maytansine- n2-deacetyl-n2-3-mercapto-1-oxopropyl-2r-pa400421000
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Maytansine, N2′-deacetyl-N2′-(3-mercapto-1-oxopropyl)-, (2′R)
Catalogue No.:PA 40 0421000
Molecular Formula : C35H48ClN3O10S
Molecular Weight : 738.29
stdClass Object
(
[pname] => DM1-SMCC
[catalogue_number] => PA 40 0421001
[category_ids] => ,79,80,71,78,70,82,
[chemical_name] =>
[weight] => 1072.62
[form] => C51H66ClN5O16S
[cas] => 1613362-80-3
[pslug] => 1613362-80-3-dm1-smcc-pa400421001
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Catalogue No.:PA 40 0421001
Molecular Formula : C51H66ClN5O16S
Molecular Weight : 1072.62
stdClass Object
(
[pname] => Spp-DM1
[catalogue_number] => PA 40 0421003
[category_ids] => ,79,80,71,78,70,82,88,170,
[chemical_name] =>
[weight] => 967.54
[form] => C44H59ClN4O14S2
[cas] => 452072-20-7
[pslug] => 452072-20-7-spp-dm1-pa400421003
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Catalogue No.:PA 40 0421003
Molecular Formula : C44H59ClN4O14S2
Molecular Weight : 967.54
stdClass Object
(
[pname] => DM4-SMe
[catalogue_number] => PA 40 0421002
[category_ids] => ,79,80,71,78,70,82,88,170,
[chemical_name] =>
[weight] => 826.46
[form] => C39H56ClN3O10S2
[cas] => 796073-68-2
[pslug] => 796073-68-2-dm4-sme-pa400421002
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Catalogue No.:PA 40 0421002
Molecular Formula : C39H56ClN3O10S2
Molecular Weight : 826.46
