rivaroxaban
Sulphur and selenium compounds
- An anticoagulant drug used to prevent blood clots. A direct factor Xa inhibitor which is taken by mouth. An oxazolidinone derivative and structurally similar to anibiotic Linezolid.Reference standards of Rivaroxaban API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
stdClass Object
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[pname] => Rivaroxaban
[catalogue_number] => PA 18 38000
[category_ids] => ,69,71,78,70,82,88,
[chemical_name] =>
[weight] => 435.88
[form] => C19H18ClN3O5S
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Catalogue No.:PA 18 38000
Molecular Formula : C19H18ClN3O5S
Molecular Weight : 435.88
stdClass Object
(
[pname] => Rivaroxaban - Impurity E
[catalogue_number] => PA 18 38510
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[chemical_name] =>
[weight] => 401.44
[form] => C19H19N3O5S
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Catalogue No.:PA 18 38510
Molecular Formula : C19H19N3O5S
Molecular Weight : 401.44
stdClass Object
(
[pname] => Rivaroxaban - Impurity F
[catalogue_number] => PA 18 38530
[category_ids] => ,88,75,71,70,76,78,82,
[chemical_name] =>
[weight] => 162.59
[form] => C5H3ClO2S
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Catalogue No.:PA 18 38530
Molecular Formula : C5H3ClO2S
Molecular Weight : 162.59
stdClass Object
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[pname] => Rivaroxaban Amide Impurity
[catalogue_number] => PA 18 38560
[category_ids] => ,79,80,92,71,78,70,82,88,
[chemical_name] =>
[weight] => 409.89
[form] => C18H20ClN3O4S
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Rivaroxaban Amide Impurity
Catalogue No.:PA 18 38560
Molecular Formula : C18H20ClN3O4S
Molecular Weight : 409.89
stdClass Object
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[catalogue_number] => PA 18 38570
[category_ids] => ,92,71,80,88,79,82,78,70,
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[weight] => 435.88
[form] => C19H18ClN3O5S
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Rivaroxaban Oxo Amine Amide Impurity
Catalogue No.:PA 18 38570
Molecular Formula : C19H18ClN3O5S
Molecular Weight : 435.88
stdClass Object
(
[pname] => Rivaroxaban Amide Dimer
[catalogue_number] => PA 18 38580
[category_ids] => ,92,79,71,70,78,80,82,88,
[chemical_name] =>
[weight] => 554.47
[form] => C23H21Cl2N3O5S2
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Catalogue No.:PA 18 38580
Molecular Formula : C23H21Cl2N3O5S2
Molecular Weight : 554.47
stdClass Object
(
[pname] => Rivaroxaban - Impurity A
[catalogue_number] => PA 18 38590
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Catalogue No.:PA 18 38590
Molecular Formula : C19H18ClN3O5S
Molecular Weight : 435.88
stdClass Object
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[catalogue_number] => PA 18 38610
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[weight] => 283.69
[form] => C11H6ClNO4S
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4-Nitrophenyl 5-chlorothiophene-2-carboxylate
Catalogue No.:PA 18 38610
Molecular Formula : C11H6ClNO4S
Molecular Weight : 283.69
stdClass Object
(
[pname] => (S)-2-(2-((4-(5-((5-Chlorothiophene-2-carboxamido)methyl)-2-oxooxazolidin-3-yl)phenyl)amino)ethoxy)acetic Acid
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(S)-2-(2-((4-(5-((5-Chlorothiophene-2-carboxamido)methyl)-2-oxooxazolidin-3-yl)phenyl)amino)ethoxy)acetic Acid
stdClass Object
(
[pname] => Rivaroxaban Open-Ring N-Methyl Impurity
[catalogue_number] => PA 18 38690
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[chemical_name] =>
[weight] => 611.52
[form] => C25H24Cl2N4O6S2
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Rivaroxaban Open-Ring N-Methyl Impurity
Catalogue No.:PA 18 38690
Molecular Formula : C25H24Cl2N4O6S2
Molecular Weight : 611.52
stdClass Object
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[catalogue_number] => PA 18 38700
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[weight] => 197.04
[form] => C5H2Cl2O2S
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4,5-Dichlorothiophene-2-carboxylic Acid
Catalogue No.:PA 18 38700
Molecular Formula : C5H2Cl2O2S
Molecular Weight : 197.04
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3,4-Dichlorothiophene-2-carboxylic Acid
Catalogue No.:PA 18 38710
Molecular Formula : C5H2Cl2O2S
Molecular Weight : 197.04
stdClass Object
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[catalogue_number] => PA 18 38720
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[weight] => 197.04
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3,5-Dichlorothiophene-2-carboxylic Acid
Catalogue No.:PA 18 38720
Molecular Formula : C5H2Cl2O2S
Molecular Weight : 197.04
stdClass Object
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[catalogue_number] => PA 18 38730
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[weight] => 231.48
[form] => C5HCl3O2S
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3,4,5-Trichlorothiophene-2-carboxylic Acid
Catalogue No.:PA 18 38730
Molecular Formula : C5HCl3O2S
Molecular Weight : 231.48
stdClass Object
(
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[catalogue_number] => PA 18 38750
[category_ids] => ,79,80,71,70,78,82,88,
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[weight] => 644.14
[form] => C30H34ClN5O7S
[cas] => NA
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5-Chloro-N-(1-hydroxy-2-((4-(3-oxomorpholino)phenyl)amino)ethyl)-N-(2-hydroxy-3-((4-(3-oxomorpholino)phenyl)amino)propyl)thiophene-2-carboxamide
Catalogue No.:PA 18 38750
Molecular Formula : C30H34ClN5O7S
Molecular Weight : 644.14
stdClass Object
(
[pname] => 5-Chloro-N-((2S)-3-((3-(5-chlorothiophene-2-carboxamido)-2-hydroxypropyl)(4-(3-oxomorpholino)phenyl)amino)-2-hydroxypropyl)thiophene-2-carboxamide
[catalogue_number] => PA 18 38760
[category_ids] => ,79,80,71,70,78,82,88,
[chemical_name] =>
[weight] => 627.56
[form] => C26H28Cl2N4O6S2
[cas] => NA
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5-Chloro-N-((2S)-3-((3-(5-chlorothiophene-2-carboxamido)-2-hydroxypropyl)(4-(3-oxomorpholino)phenyl)amino)-2-hydroxypropyl)thiophene-2-carboxamide
Catalogue No.:PA 18 38760
Molecular Formula : C26H28Cl2N4O6S2
Molecular Weight : 627.56
stdClass Object
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[pname] => Rivaroxaban - Impurity D
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[weight] => 608.6
[form] => C29H32N6O9
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stdClass Object
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[catalogue_number] => PA 18 38780
[category_ids] => ,79,80,71,70,78,82,88,
[chemical_name] =>
[weight] => 490.36
[form] => C19H21Cl2N3O6S
[cas] => 931117-61-2
[pslug] => 931117-61-2-2--2--4--5s--5--5-chloro-2-thienyl-carbonyl-amino-methyl--2-oxo-3-oxazolidinyl-phenyl-amino-ethoxy--acetic-acid-hydrochloride-pa1838780
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2-[2-[[4-[(5S)-5-[[[(5-Chloro-2-thienyl)carbonyl]amino]methyl]-2-oxo-3-oxazolidinyl]phenyl]amino]ethoxy]-acetic Acid Hydrochloride
Catalogue No.:PA 18 38780
Molecular Formula : C19H21Cl2N3O6S
Molecular Weight : 490.36
stdClass Object
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[pname] => Rivaroxaban - Impurity J
[catalogue_number] => PA 18 38790
[category_ids] => ,92,88,82,80,79,78,71,70,
[chemical_name] =>
[weight] => 871.76
[form] => C38H36Cl2N6O10S2
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Catalogue No.:PA 18 38790
Molecular Formula : C38H36Cl2N6O10S2
Molecular Weight : 871.76
stdClass Object
(
[pname] => 2-Chlorothiophene
[catalogue_number] => PA 18 38880
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[chemical_name] =>
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Catalogue No.:PA 18 38880
Molecular Formula : C4H3ClS
Molecular Weight : 118.58
stdClass Object
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2-Acetyl-5-chlorothiophene
Catalogue No.:PA 18 38890
Molecular Formula : C6H5ClOS
Molecular Weight : 160.62
stdClass Object
(
[pname] => 2-Thiophenecarboxylic Acid
[catalogue_number] => PA 18 38900
[category_ids] => ,84,88,75,
[chemical_name] =>
[weight] => 128.15
[form] => C5H4O2S
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2-Thiophenecarboxylic Acid
Catalogue No.:PA 18 38900
Molecular Formula : C5H4O2S
Molecular Weight : 128.15
stdClass Object
(
[pname] => Sodium Thiophene-2-carboxylate
[catalogue_number] => PA 19 15000
[category_ids] => ,70,78,82,88,
[chemical_name] =>
[weight] => 150.13
[form] => C5H3NaO2S
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Sodium Thiophene-2-carboxylate
Catalogue No.:PA 19 15000
Molecular Formula : C5H3NaO2S
Molecular Weight : 150.13
stdClass Object
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[catalogue_number] => PA STI 078220
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[chemical_name] =>
[weight] => 439.91
[form] => C19H14D4ClN3O5S
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Catalogue No.:PA STI 078220
Molecular Formula : C19H14D4ClN3O5S
Molecular Weight : 439.91
stdClass Object
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[catalogue_number] => PA 18 38090
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[weight] => 598.47
[form] => C24H21Cl2N3O7S2
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Catalogue No.:PA 18 38090
Molecular Formula : C24H21Cl2N3O7S2
Molecular Weight : 598.47
stdClass Object
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[catalogue_number] => PA 18 38950
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[weight] => 175.63
[form] => C6H6ClNOS
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5-Chloro-N-methylthiophene-2-carboxamide
Catalogue No.:PA 18 38950
Molecular Formula : C6H6ClNOS
Molecular Weight : 175.63
stdClass Object
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[catalogue_number] => PA 18 38565
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[weight] => 453.9
[form] => C19H20ClN3O6S
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Rivaroxaban Diol (Mixture of Diastereomers)
stdClass Object
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[catalogue_number] => PA 18 38910
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[weight] => 451.88
[form] => C19H18ClN3O6S
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Catalogue No.:PA 18 38910
Molecular Formula : C19H18ClN3O6S
Molecular Weight : 451.88
stdClass Object
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[catalogue_number] => PA 18 0381058
[category_ids] => ,69,70,71,78,82,88,162,
[chemical_name] =>
[weight] => 438.88
[form] => C18H19ClN4O5S
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5-Chloro-N-(2-hydroxy-3-(nitroso(4-(3-oxomorpholino)phenyl)amino)propyl)thiophene-2-carboxamide
Catalogue No.:PA 18 0381058
Molecular Formula : C18H19ClN4O5S
Molecular Weight : 438.88
stdClass Object
(
[pname] => Contezolid
[catalogue_number] => PA 18 0381066
[category_ids] => ,69,71,78,70,82,88,
[chemical_name] =>
[weight] => 408.34
[form] => C18H15F3N4O4
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Catalogue No.:PA 18 0381066
Molecular Formula : C18H15F3N4O4
Molecular Weight : 408.34
stdClass Object
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[catalogue_number] => PA 18 0381075
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[weight] => 435.88
[form] => C19H18ClN3O5S
[cas] => 1879903-65-7
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Rivaroxaban (R)-Isomer Oxo Amine Amide Impurity
Catalogue No.:PA 18 0381075
Molecular Formula : C19H18ClN3O5S
Molecular Weight : 435.88
stdClass Object
(
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[catalogue_number] => PA 18 0381081
[category_ids] => ,69,71,78,70,82,88,162,
[chemical_name] =>
[weight] => 424.41
[form] => C21H20N4O6
[cas] => NA
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N-(3-(1,3-Dioxoisoindolin-2-yl)-2-hydroxypropyl)-N-(4-(3-oxomorpholino)phenyl)nitrous amide
Catalogue No.:PA 18 0381081
Molecular Formula : C21H20N4O6
Molecular Weight : 424.41
stdClass Object
(
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[catalogue_number] => PA 18 0381085
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[weight] => 395.42
[form] => C21H21N3O5
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2-(2-Hydroxy-3-((4-(3-oxomorpholino)phenyl)amino)propyl)isoindoline-1,3-dione
Catalogue No.:PA 18 0381085
Molecular Formula : C21H21N3O5
Molecular Weight : 395.42
stdClass Object
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[catalogue_number] => PA 18 0381086
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[weight] => 391.87
[form] => C18H18ClN3O3S
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Catalogue No.:PA 18 0381086
Molecular Formula : C18H18ClN3O3S
Molecular Weight : 391.87
stdClass Object
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[catalogue_number] => PA 18 0381087
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[weight] => 279.34
[form] => C14H21N3O3
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Rivaroxaban Open Ring Methylamine
Catalogue No.:PA 18 0381087
Molecular Formula : C14H21N3O3
Molecular Weight : 279.34
stdClass Object
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[pname] => Rivaroxaban Phthalimido Ethyl Ester Analog
[catalogue_number] => PA 18 0381088
[category_ids] => ,69,71,78,70,82,88,
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[weight] => 612.05
[form] => C29H26ClN3O8S
[cas] => 2206826-56-2
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Rivaroxaban Phthalimido Ethyl Ester Analog
Catalogue No.:PA 18 0381088
Molecular Formula : C29H26ClN3O8S
Molecular Weight : 612.05
stdClass Object
(
[pname] => (S)-5-Chloro-N-(3-(5-chlorothiophene-2-carboxamido)-2-hydroxypropyl)-N-(4-(3-oxomorpholino)phenyl)thiophene-2-carboxamide
[catalogue_number] => PA 18 0381089
[category_ids] => ,92,79,71,70,78,80,82,88,
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[weight] => 554.46
[form] => C23H21Cl2N3O5S2
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Catalogue No.:PA 18 0381089
Molecular Formula : C23H21Cl2N3O5S2
Molecular Weight : 554.46
stdClass Object
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(S)-2-(2-((4-(5-(Aminomethyl)-2-oxooxazolidin-3-yl)phenyl)amino)ethoxy)-N-methylacetamide
Catalogue No.:PA 18 0381090
Molecular Formula : C15H22N4O4
Molecular Weight : 322.37
stdClass Object
(
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[weight] => 351.36
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(S)-2-(2-((4-(5-(Aminomethyl)-2-oxooxazolidin-3-yl)phenyl)(nitroso)amino)ethoxy)-N-methylacetamide
Catalogue No.:PA 18 0381091
Molecular Formula : C15H21N5O5
Molecular Weight : 351.36
stdClass Object
(
[pname] => 1-(4-Chlorothiophen-2-yl)ethan-1-one
[catalogue_number] => PA 18 0381092
[category_ids] => ,69,71,78,70,82,88,
[chemical_name] =>
[weight] => 160.62
[form] => C6H5ClOS
[cas] => 34730-20-6
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1-(4-Chlorothiophen-2-yl)ethan-1-one
Catalogue No.:PA 18 0381092
Molecular Formula : C6H5ClOS
Molecular Weight : 160.62
stdClass Object
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[weight] => 424.41
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(S)-N-(3-(1,3-Dioxoisoindolin-2-yl)-2-hydroxypropyl)-N-(4-(3-oxomorpholino)phenyl)nitrous amide
Catalogue No.:PA 18 0381095
Molecular Formula : C21H20N4O6
Molecular Weight : 424.41
stdClass Object
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[catalogue_number] => PA 18 0381101
[category_ids] => ,76,75,78,70,82,88,
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[weight] => 197.03
[form] => C5H2Cl2O2S
[cas] => 36157-41-2
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2,5-Dichlorothiophene-3-carboxylic Acid
Catalogue No.:PA 18 0381101
Molecular Formula : C5H2Cl2O2S
Molecular Weight : 197.03
