Rivaroxaban-impurities | Pharmaffiliates

rivaroxaban

An anticoagulant drug used to prevent blood clots. A direct factor Xa inhibitor which is taken by mouth. An oxazolidinone derivative and structurally similar to anibiotic Linezolid.Reference standards of Rivaroxaban API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

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    [pname] => Rivaroxaban - API Standards 
    [catalogue_number] => PA 18 38000
    [category_ids] => ,69,71,78,70,82,88,
    [chemical_name] => 
    [weight] => 435.88
    [form] => C19H18ClN3O5S
    [cas] => 366789-02-8
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PA 18 38000

Rivaroxaban - API Standards


  • Catalogue No.:PA 18 38000

  • CAS :

    366789-02-8

  • Molecular Formula : C19H18ClN3O5S

  • Molecular Weight : 435.88

stdClass Object
(
    [pname] => Rivaroxaban - Impurity E
    [catalogue_number] => PA 18 38510
    [category_ids] => ,69,70,71,78,82,88,
    [chemical_name] => 
    [weight] => 401.44
    [form] => C19H19N3O5S
    [cas] => 1415566-28-7
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PA 18 38510

Rivaroxaban - Impurity E


  • Catalogue No.:PA 18 38510

  • CAS :

    1415566-28-7

  • Molecular Formula : C19H19N3O5S

  • Molecular Weight : 401.44

stdClass Object
(
    [pname] => Rivaroxaban Amide Impurity
    [catalogue_number] => PA 18 38560
    [category_ids] => ,79,80,92,71,78,70,82,88,
    [chemical_name] => 
    [weight] => 409.89
    [form] => C18H20ClN3O4S
    [cas] => 721401-53-2
    [pslug] => 721401-53-2-rivaroxaban-amide-impurity-pa1838560
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PA 18 38560

Rivaroxaban Amide Impurity


  • Catalogue No.:PA 18 38560

  • CAS :

    721401-53-2

  • Molecular Formula : C18H20ClN3O4S

  • Molecular Weight : 409.89

stdClass Object
(
    [pname] => Rivaroxaban Oxo Amine Amide Impurity
    [catalogue_number] => PA 18 38570
    [category_ids] => 92,71,80,88,79,82,78,70
    [chemical_name] => 
    [weight] => 435.88
    [form] => C19H18ClN3O5S
    [cas] => 1838139-24-4
    [pslug] => 1838139-24-4-rivaroxaban-oxo-amine-amide-impurity-pa1838570
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PA 18 38570

Rivaroxaban Oxo Amine Amide Impurity


  • Catalogue No.:PA 18 38570

  • CAS :

    1838139-24-4

  • Molecular Formula : C19H18ClN3O5S

  • Molecular Weight : 435.88

stdClass Object
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    [pname] => Rivaroxaban - Impurity A
    [catalogue_number] => PA 18 38590
    [category_ids] => 92,88,82,80,79,78,71,70
    [chemical_name] => 
    [weight] => 435.88
    [form] => C19H18ClN3O5S
    [cas] => 865479-71-6
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PA 18 38590

Rivaroxaban - Impurity A


  • Catalogue No.:PA 18 38590

  • CAS :

    865479-71-6

  • Molecular Formula : C19H18ClN3O5S

  • Molecular Weight : 435.88

stdClass Object
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    [pname] => 4-Nitrophenyl 5-chlorothiophene-2-carboxylate
    [catalogue_number] => PA 18 38610
    [category_ids] => ,80,71,78,70,82,88,
    [chemical_name] => 
    [weight] => 283.69
    [form] => C11H6ClNO4S
    [cas] => 1450877-56-1
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PA 18 38610

4-Nitrophenyl 5-chlorothiophene-2-carboxylate


  • Catalogue No.:PA 18 38610

  • CAS :

    1450877-56-1

  • Molecular Formula : C11H6ClNO4S

  • Molecular Weight : 283.69

stdClass Object
(
    [pname] => (S)-2-(2-((4-(5-((5-Chlorothiophene-2-carboxamido)methyl)-2-oxooxazolidin-3-yl)phenyl)amino)ethoxy)acetic Acid
    [catalogue_number] => PA 18 38680
    [category_ids] => ,69,71,76,75,78,70,82,88,
    [chemical_name] => 
    [weight] => 453.9
    [form] => C19H20ClN3O6S
    [cas] => 931204-39-6
    [pslug] => 931204-39-6-s-2-2-4-5-5-chlorothiophene-2-carboxamido-methyl-2-oxooxazolidin-3-yl-phenyl-amino-ethoxy-acetic-acid-pa1838680
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PA 18 38680

(S)-2-(2-((4-(5-((5-Chlorothiophene-2-carboxamido)methyl)-2-oxooxazolidin-3-yl)phenyl)amino)ethoxy)acetic Acid


  • Catalogue No.:PA 18 38680

  • CAS :

    931204-39-6

  • Molecular Formula : C19H20ClN3O6S

  • Molecular Weight : 453.9

stdClass Object
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    [pname] => 4,5-Dichlorothiophene-2-carboxylic Acid
    [catalogue_number] => PA 18 38700
    [category_ids] => ,76,75,78,70,82,88,
    [chemical_name] => 
    [weight] => 197.04
    [form] => C5H2Cl2O2S
    [cas] => 31166-29-7
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PA 18 38700

4,5-Dichlorothiophene-2-carboxylic Acid


  • Catalogue No.:PA 18 38700

  • CAS :

    31166-29-7

  • Molecular Formula : C5H2Cl2O2S

  • Molecular Weight : 197.04

stdClass Object
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    [pname] => 3,4-Dichlorothiophene-2-carboxylic Acid
    [catalogue_number] => PA 18 38710
    [category_ids] => ,76,75,78,70,82,88,
    [chemical_name] => 
    [weight] => 197.04
    [form] => C5H2Cl2O2S
    [cas] => 61209-02-7
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PA 18 38710

3,4-Dichlorothiophene-2-carboxylic Acid


  • Catalogue No.:PA 18 38710

  • CAS :

    61209-02-7

  • Molecular Formula : C5H2Cl2O2S

  • Molecular Weight : 197.04

stdClass Object
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    [pname] => 3,5-Dichlorothiophene-2-carboxylic Acid
    [catalogue_number] => PA 18 38720
    [category_ids] => ,76,75,78,70,82,88,
    [chemical_name] => 
    [weight] => 197.04
    [form] => C5H2Cl2O2S
    [cas] => 89166-94-9
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PA 18 38720

3,5-Dichlorothiophene-2-carboxylic Acid


  • Catalogue No.:PA 18 38720

  • CAS :

    89166-94-9

  • Molecular Formula : C5H2Cl2O2S

  • Molecular Weight : 197.04

stdClass Object
(
    [pname] => 3,4,5-Trichlorothiophene-2-carboxylic Acid
    [catalogue_number] => PA 18 38730
    [category_ids] => ,76,75,78,70,82,88,
    [chemical_name] => 
    [weight] => 231.48
    [form] => C5HCl3O2S
    [cas] => 26020-48-4
    [pslug] => 26020-48-4-3-4-5-trichlorothiophene-2-carboxylic-acid-pa1838730
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PA 18 38730

3,4,5-Trichlorothiophene-2-carboxylic Acid


  • Catalogue No.:PA 18 38730

  • CAS :

    26020-48-4

  • Molecular Formula : C5HCl3O2S

  • Molecular Weight : 231.48

stdClass Object
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    [pname] => 5-Chloro-N-(1-hydroxy-2-((4-(3-oxomorpholino)phenyl)amino)ethyl)-N-(2-hydroxy-3-((4-(3-oxomorpholino)phenyl)amino)propyl)thiophene-2-carboxamide
    [catalogue_number] => PA 18 38750
    [category_ids] => ,79,80,71,70,78,82,88,
    [chemical_name] => 
    [weight] => 644.14
    [form] => C30H34ClN5O7S
    [cas] => NA
    [pslug] => 5-chloro-n-1-hydroxy-2-4-3-oxomorpholino-phenyl-amino-ethyl-n-2-hydroxy-3-4-3-oxomorpholino-phenyl-amino-propyl-thiophene-2-carboxamide-pa1838750
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PA 18 38750

5-Chloro-N-(1-hydroxy-2-((4-(3-oxomorpholino)phenyl)amino)ethyl)-N-(2-hydroxy-3-((4-(3-oxomorpholino)phenyl)amino)propyl)thiophene-2-carboxamide


  • Catalogue No.:PA 18 38750

  • CAS :

    NA

  • Molecular Formula : C30H34ClN5O7S

  • Molecular Weight : 644.14

stdClass Object
(
    [pname] => 5-Chloro-N-((2S)-3-((3-(5-chlorothiophene-2-carboxamido)-2-hydroxypropyl)(4-(3-oxomorpholino)phenyl)amino)-2-hydroxypropyl)thiophene-2-carboxamide
    [catalogue_number] => PA 18 38760
    [category_ids] => ,79,80,71,70,78,82,88,
    [chemical_name] => 
    [weight] => 627.56
    [form] => C26H28Cl2N4O6S2
    [cas] => NA
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PA 18 38760

5-Chloro-N-((2S)-3-((3-(5-chlorothiophene-2-carboxamido)-2-hydroxypropyl)(4-(3-oxomorpholino)phenyl)amino)-2-hydroxypropyl)thiophene-2-carboxamide


  • Catalogue No.:PA 18 38760

  • CAS :

    NA

  • Molecular Formula : C26H28Cl2N4O6S2

  • Molecular Weight : 627.56

stdClass Object
(
    [pname] => 2-​[2-​[[4-​[(5S)​-​5-​[[[(5-Chloro-​2-​thienyl)​carbonyl]​amino]​methyl]​-​2-​oxo-​3-​oxazolidinyl]​phenyl]​amino]​ethoxy]​-acetic Acid Hydrochloride
    [catalogue_number] => PA 18 38780
    [category_ids] => ,79,80,71,70,78,82,88,
    [chemical_name] => 
    [weight] => 490.36
    [form] => C19H21Cl2N3O6S
    [cas] => 931117-61-2
    [pslug] => 931117-61-2-2-​-2-​-4-​-5s-​-​5-​-5-chloro-​2-​thienyl-​carbonyl-​amino-​methyl-​-​2-​oxo-​3-​oxazolidinyl-​phenyl-​amino-​ethoxy-​-acetic-acid-hydrochloride-pa1838780
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PA 18 38780

2-​[2-​[[4-​[(5S)​-​5-​[[[(5-Chloro-​2-​thienyl)​carbonyl]​amino]​methyl]​-​2-​oxo-​3-​oxazolidinyl]​phenyl]​amino]​ethoxy]​-acetic Acid Hydrochloride


  • Catalogue No.:PA 18 38780

  • CAS :

    931117-61-2

  • Molecular Formula : C19H21Cl2N3O6S

  • Molecular Weight : 490.36

stdClass Object
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    [pname] => Rivaroxaban - Impurity J
    [catalogue_number] => PA 18 38790
    [category_ids] => 92,80,79,88,70,78,82,71
    [chemical_name] => 
    [weight] => 871.76
    [form] => C38H36Cl2N6O10S2
    [cas] => 1632463-24-1
    [pslug] => 1632463-24-1-rivaroxaban-impurity-j-pa1838790
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PA 18 38790

Rivaroxaban - Impurity J


  • Catalogue No.:PA 18 38790

  • CAS :

    1632463-24-1

  • Molecular Formula : C38H36Cl2N6O10S2

  • Molecular Weight : 871.76

stdClass Object
(
    [pname] => 2-Chlorothiophene
    [catalogue_number] => PA 18 38880
    [category_ids] => ,84,88,75,
    [chemical_name] => 
    [weight] => 118.58
    [form] => C4H3ClS
    [cas] => 96-43-5
    [pslug] => 96-43-5-2-chlorothiophene-pa1838880
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PA 18 38880

2-Chlorothiophene


  • Catalogue No.:PA 18 38880

  • CAS :

    96-43-5

  • Molecular Formula : C4H3ClS

  • Molecular Weight : 118.58

stdClass Object
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    [pname] => 2-Acetyl-5-chlorothiophene
    [catalogue_number] => PA 18 38890
    [category_ids] => ,75,84,88,
    [chemical_name] => 
    [weight] => 160.62
    [form] => C6H5ClOS
    [cas] => 6310-09-4
    [pslug] => 6310-09-4-2-acetyl-5-chlorothiophene-pa1838890
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PA 18 38890

2-Acetyl-5-chlorothiophene


  • Catalogue No.:PA 18 38890

  • CAS :

    6310-09-4

  • Molecular Formula : C6H5ClOS

  • Molecular Weight : 160.62

stdClass Object
(
    [pname] => 2-Thiophenecarboxylic Acid
    [catalogue_number] => PA 18 38900
    [category_ids] => ,84,88,75,
    [chemical_name] => 
    [weight] => 128.15
    [form] => C5H4O2S
    [cas] => 527-72-0
    [pslug] => 527-72-0-2-thiophenecarboxylic-acid-pa1838900
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PA 18 38900

2-Thiophenecarboxylic Acid


  • Catalogue No.:PA 18 38900

  • CAS :

    527-72-0

  • Molecular Formula : C5H4O2S

  • Molecular Weight : 128.15

stdClass Object
(
    [pname] => Rivaroxaban-d4
    [catalogue_number] => PA STI 078220
    [category_ids] => ,69,71,98,78,70,82,88,
    [chemical_name] => 
    [weight] => 439.91
    [form] => C19H14D4ClN3O5S
    [cas] => 1132681-38-9
    [pslug] => 1132681-38-9-rivaroxaban-d4-pasti078220
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PA STI 078220

Rivaroxaban-d4


  • Catalogue No.:PA STI 078220

  • CAS :

    1132681-38-9

  • Molecular Formula : C19H14D4ClN3O5S

  • Molecular Weight : 439.91

stdClass Object
(
    [pname] => Rivaroxaban - Impurity I
    [catalogue_number] => PA 18 38090
    [category_ids] => ,70,71,75,78,79,80,82,88,
    [chemical_name] => 
    [weight] => 598.47
    [form] => C24H21Cl2N3O7S2
    [cas] => 1151893-81-0
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PA 18 38090

Rivaroxaban - Impurity I


  • Catalogue No.:PA 18 38090

  • CAS :

    1151893-81-0

  • Molecular Formula : C24H21Cl2N3O7S2

  • Molecular Weight : 598.47

stdClass Object
(
    [pname] => 5-Chloro-N-methylthiophene-2-carboxamide
    [catalogue_number] => PA 18 38950
    [category_ids] => ,75,88,78,70,82,
    [chemical_name] => 
    [weight] => 175.63
    [form] => C6H6ClNOS
    [cas] => 97799-98-9
    [pslug] => 97799-98-9-5-chloro-n-methylthiophene-2-carboxamide-pa1838950
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PA 18 38950

5-Chloro-N-methylthiophene-2-carboxamide


  • Catalogue No.:PA 18 38950

  • CAS :

    97799-98-9

  • Molecular Formula : C6H6ClNOS

  • Molecular Weight : 175.63

stdClass Object
(
    [pname] => Rivaroxaban Diol (Mixture of Diastereomers)
    [catalogue_number] => PA 18 38565
    [category_ids] => ,69,71,76,75,78,70,82,88,
    [chemical_name] => 
    [weight] => 453.9
    [form] => C19H20ClN3O6S
    [cas] => 1160170-00-2
    [pslug] => 1160170-00-2-rivaroxaban-diol-mixture-of-diastereomers-pa1838565
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PA 18 38565

Rivaroxaban Diol (Mixture of Diastereomers)


  • Catalogue No.:PA 18 38565

  • CAS :

    1160170-00-2

  • Molecular Formula : C19H20ClN3O6S

  • Molecular Weight : 453.9

stdClass Object
(
    [pname] => Rivaroxaban Sulfoxide
    [catalogue_number] => PA 18 38910
    [category_ids] => ,71,78,70,82,88,
    [chemical_name] => 
    [weight] => 451.88
    [form] => C19H18ClN3O6S
    [cas] => 2197189-38-9
    [pslug] => 2197189-38-9-rivaroxaban-sulfoxide-pa1838910
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PA 18 38910

Rivaroxaban Sulfoxide


  • Catalogue No.:PA 18 38910

  • CAS :

    2197189-38-9

  • Molecular Formula : C19H18ClN3O6S

  • Molecular Weight : 451.88

stdClass Object
(
    [pname] => 5-Chloro-N-(2-hydroxy-3-(nitroso(4-(3-oxomorpholino)phenyl)amino)propyl)thiophene-2-carboxamide
    [catalogue_number] => PA 18 0381058
    [category_ids] => ,69,70,71,78,82,88,162,
    [chemical_name] => 
    [weight] => 438.88
    [form] => C18H19ClN4O5S
    [cas] => NA
    [pslug] => 5-chloro-n-2-hydroxy-3-nitroso-4-3-oxomorpholino-phenyl-amino-propyl-thiophene-2-carboxamide-pa180381058
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PA 18 0381058

5-Chloro-N-(2-hydroxy-3-(nitroso(4-(3-oxomorpholino)phenyl)amino)propyl)thiophene-2-carboxamide


  • Catalogue No.:PA 18 0381058

  • CAS :

    NA

  • Molecular Formula : C18H19ClN4O5S

  • Molecular Weight : 438.88

stdClass Object
(
    [pname] => Contezolid
    [catalogue_number] => PA 18 0381066
    [category_ids] => ,69,71,78,70,82,88,
    [chemical_name] => 
    [weight] => 408.34
    [form] => C18H15F3N4O4
    [cas] => 1112968-42-9
    [pslug] => 1112968-42-9-contezolid-pa180381066
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PA 18 0381066

Contezolid


  • Catalogue No.:PA 18 0381066

  • CAS :

    1112968-42-9

  • Molecular Formula : C18H15F3N4O4

  • Molecular Weight : 408.34

stdClass Object
(
    [pname] => Rivaroxaban (R)-Isomer Oxo Amine Amide Impurity
    [catalogue_number] => PA 18 0381075
    [category_ids] => ,69,71,78,70,82,88,
    [chemical_name] => 
    [weight] => 435.88
    [form] => C19H18ClN3O5S
    [cas] => 1879903-65-7
    [pslug] => 1879903-65-7-rivaroxaban-r-isomer-oxo-amine-amide-impurity-pa180381075
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PA 18 0381075

Rivaroxaban (R)-Isomer Oxo Amine Amide Impurity


  • Catalogue No.:PA 18 0381075

  • CAS :

    1879903-65-7

  • Molecular Formula : C19H18ClN3O5S

  • Molecular Weight : 435.88

stdClass Object
(
    [pname] => N-(3-(1,3-Dioxoisoindolin-2-yl)-2-hydroxypropyl)-N-(4-(3-oxomorpholino)phenyl)nitrous amide
    [catalogue_number] => PA 18 0381081
    [category_ids] => ,69,71,78,70,82,88,162,
    [chemical_name] => 
    [weight] => 424.41
    [form] => C21H20N4O6
    [cas] => NA
    [pslug] => n-3-1-3-dioxoisoindolin-2-yl-2-hydroxypropyl-n-4-3-oxomorpholino-phenyl-nitrous-amide-pa180381081
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PA 18 0381081

N-(3-(1,3-Dioxoisoindolin-2-yl)-2-hydroxypropyl)-N-(4-(3-oxomorpholino)phenyl)nitrous amide


  • Catalogue No.:PA 18 0381081

  • CAS :

    NA

  • Molecular Formula : C21H20N4O6

  • Molecular Weight : 424.41