leflunomide
Tyrosine kinase inhibitors
- An immunomodulatory drug, Leflunomide is used to treat rheumatoid arthritis and psoriatic arthritis. An inhibitor of enzyme dihydroorotate dehydrogenase which plays a key role in the synthesis of uridine monophosphate (rUMP), which is required for the synthesis of DNA and RNA. Reference standards of Leflunomide API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
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[pname] => Leflunomide - Impurity B
[catalogue_number] => PA 12 08020
[category_ids] => ,117,76,82,78,75,70,
[chemical_name] =>
[weight] => 270.21
[form] => C12H9F3N2O2
[cas] => 163451-81-8
[pslug] => 163451-81-8-leflunomide-impurity-b-pa1208020
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Catalogue No.:PA 12 08020
Molecular Formula : C12H9F3N2O2
Molecular Weight : 270.21
stdClass Object
(
[pname] => A77 1726-d4
[catalogue_number] => PA STI 008740
[category_ids] => ,76,75,117,98,
[chemical_name] =>
[weight] => 274.23
[form] => C12H5D4F3N2O2
[cas] => 1185240-22-5
[pslug] => 1185240-22-5-a77-1726-d4-pasti008740
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Catalogue No.:PA STI 008740
Molecular Formula : C12H5D4F3N2O2
Molecular Weight : 274.23
stdClass Object
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[pname] => 2-Cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)but-2-enamide
[catalogue_number] => PA 12 08530
[category_ids] => ,117,76,82,78,75,70,
[chemical_name] =>
[weight] => 270.21
[form] => C12H9F3N2O2
[cas] => 108605-62-5
[pslug] => 108605-62-5-2-cyano-3-hydroxy-n-4-trifluoromethyl-phenyl-but-2-enamide-pa1208530
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2-Cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)but-2-enamide
Catalogue No.:PA 12 08530
Molecular Formula : C12H9F3N2O2
Molecular Weight : 270.21
