Catalogue number: | PA 27 0030843 |
Chemical name: | Azido-PEG8-acid |
CAS Number: |
1214319-92-2 |
Category: | miscellaneous compounds,Antibody Drug Conjugate |
Synonyms: | 1-azido-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oic acid; Propanoic acid, 3-[(23-azido-3,6,9,12,15,18,21-heptaoxatricos-1-yl)oxy]-; 3-[(23-Azido-3,6,9,12,15,18,21-heptaoxatricos-1-yl)oxy]propanoic acid; Azido-dPEG8 acid; |
Molecular form: | C19H37N3O10 |
Appearance: | Viscous Liquid |
Mol. Weight: | 467.52 |
Storage: | 2-8°C Refrigerator |
Shipping Conditions: | Ambient |
Applications: | Azido-PEG8-acid is a non-cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG8-acid is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG8-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups |
Azido-PEG8-acid
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