Catalogue number: | PA 27 0030396 |
Chemical name: | Aminooxy-PEG2-azide |
CAS Number: |
1043426-13-6 |
Category: | miscellaneous compounds,Antibody Drug Conjugate |
Synonyms: | O-(2-(2-(2-azidoethoxy)ethoxy)ethyl)hydroxylamine; Ethane, 1-[2-(aminooxy)ethoxy]-2-(2-azidoethoxy)-; 1-[2-(Aminooxy)ethoxy]-2-(2-azidoethoxy)ethane; |
Molecular form: | C6H14N4O3 |
Appearance: | Liquid |
Mol. Weight: | 190.2 |
Storage: | 2-8°C Refrigerator |
Shipping Conditions: | Ambient |
Applications: | Aminooxy-PEG2-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Aminooxy-PEG2-azide is also a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2]. Aminooxy-PEG2-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups |
Aminooxy-PEG2-azide
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