Catalogue number: | PA 27 0030413 |
Chemical name: | N3-PEG3-CH2CH2COOH |
CAS Number: |
1056024-94-2 |
Category: | miscellaneous compounds,Antibody Drug Conjugate |
Synonyms: | 3-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)propanoic acid; Propanoic acid, 3-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]-; 3-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]propanoic acid; 12-Azido-4,7,10-trioxadodecanoic acid; |
Molecular form: | C9H17N3O5 |
Appearance: | Liquid |
Mol. Weight: | 247.25 |
Storage: | 2-8°C Refrigerator |
Shipping Conditions: | Ambient |
Applications: | N3-PEG3-CH2CH2COOH a PEG-based PROTAC linker can be used in the synthesis of BI-3663 (HY-111546), BI-4216 and BI-0319. Azido-PEG3-acid is also a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N3-PEG3-CH2CH2COOH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups |
N3-PEG3-CH2CH2COOH
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