| Catalogue number: | PA 27 0030838 |
| Chemical name: | Azido-PEG8-NHS ester |
CAS Number: |
1204834-00-3 |
| Category: | miscellaneous compounds,Antibody Drug Conjugate |
| Synonyms: | Propanoic acid, 3-[(23-azido-3,6,9,12,15,18,21-heptaoxatricos-1-yl)oxy]-, 2,5-dioxo-1-pyrrolidinyl ester; 2,5-Dioxo-1-pyrrolidinyl 3-[(23-azido-3,6,9,12,15,18,21-heptaoxatricos-1-yl)oxy]propanoate; Azido-dPEG8-NHS ester; |
| Molecular form: | C23H40N4O12 |
| Appearance: | Liquid |
| Mol. Weight: | 564.59 |
| Storage: | 2-8°C Refrigerator |
| Shipping Conditions: | Ambient |
| Applications: | Azido-PEG8-NHS ester is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Azido-PEG8-NHS ester is also a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[2]. Azido-PEG8-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups |
Azido-PEG8-NHS ester
Azido-PEG8-NHS ester
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