| Catalogue number: | PA 27 0030861 |
| Chemical name: | DBCO-PEG4 amine |
CAS Number: |
1255942-08-5 |
| Category: | miscellaneous compounds,Antibody Drug Conjugate |
| Synonyms: | 4,7,10,13-Tetraoxapentadecanamide, 15-amino-N-[3-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-3-oxopropyl]-; 15-Amino-N-[3-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-3-oxopropyl]-4,7,10,13-tetraoxapentadecanamide; ADIBO-PEG4-amine; |
| Molecular form: | C29H37N3O6 |
| Appearance: | NA |
| Mol. Weight: | 523.63 |
| Storage: | 2-8°C Refrigerator |
| Shipping Conditions: | Ambient |
| Applications: | DBCO-NHCO-PEG4-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-NHCO-PEG4-amine is a cleavable ADC linker used to conjugate MMAE (HY-15162) and antibody (e.g., DBCO-VCpAB−MMAE and DBCO-TRX−MMAE with EC50s of 280 nM and 22 nM in SKBR3 cells, respectively) |
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