Catalogue number: | PA 27 0031203 |
Chemical name: | N-Succinimidyl 4-Azido-2,3,5,6-tetrafluorobenzoate |
CAS Number: |
126695-58-7 |
Category: | miscellaneous compounds,Antibody Drug Conjugate |
Synonyms: | Benzoic acid, 4-azido-2,3,5,6-tetrafluoro-, 2,5-dioxo-1-pyrrolidinyl ester; 2,5-Pyrrolidinedione, 1-[(4-azido-2,3,5,6-tetrafluorobenzoyl)oxy]-; 4-Azido-tetrafluorobenzoate N-hydroxysuccinimidyl ester; N-Succinimidyl 4-azidotetrafluorobenzoate; ATFB-SE; |
Molecular form: | C11H4F4N4O4 |
Appearance: | NA |
Mol. Weight: | 332.17 |
Storage: | 2-8°C Refrigerator |
Shipping Conditions: | Ambient |
Applications: | 4-N3Pfp-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. 4-N3Pfp-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups |
N-Succinimidyl 4-Azido-2,3,5,6-tetrafluorobenzoate
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