DBCO-NHS ester

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Catalogue number:	PA 27 0031239
Chemical name:	DBCO-NHS ester
CAS Number:	1353016-71-3
Category:	miscellaneous compounds,Antibody Drug Conjugate
Synonyms:	Dibenz[b,f]azocine-5(6H)-butanoic acid, 11,12-didehydro-γ-oxo-, 2,5-dioxo-1-pyrrolidinyl ester; 2,5-Dioxo-1-pyrrolidinyl 11,12-didehydro-γ-oxodibenz[b,f]azocine-5(6H)-butanoate; 1-[[4-[11,12-Didehydrodibenzo[b,f]azocin-5(6H)-yl]-4-oxobutanoyl]oxy]pyrrolidine-2,5-dione; 2,5-Dioxopyrrolidinyl γ-oxo-11,12-didehydro-5,6-dihydrodibenz[b,f]azocine-5-butanoate; DIBAC-NHS Ester;
Molecular form:	C₂₃H₁₈N₂O₅
Appearance:	Solid
Mol. Weight:	402.41
Storage:	2-8°C Refrigerator
Shipping Conditions:	Ambient
Applications:	DBCO-NHS ester is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.