Catalogue number: | PA 27 0031398 |
Chemical name: | Aminoxyacetamide-PEG3-azide |
CAS Number: |
1379761-16-6 |
Category: | miscellaneous compounds,Antibody Drug Conjugate |
Synonyms: | 2-(aminooxy)-N-(2-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)ethyl)acetamide; Acetamide, 2-(aminooxy)-N-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethyl]-; |
Molecular form: | C10H21N5O5 |
Appearance: | NA |
Mol. Weight: | 291.31 |
Storage: | 2-8°C Refrigerator |
Shipping Conditions: | Ambient |
Applications: | Aminoxyacetamide-PEG3-azide is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Aminoxyacetamide-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups |
Aminoxyacetamide-PEG3-azide
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