| Catalogue number: | PA 27 0031409 |
| Chemical name: | DBCO-NHS ester 3 |
CAS Number: |
1393350-27-0 |
| Category: | miscellaneous compounds,Antibody Drug Conjugate |
| Synonyms: | Dibenz[b,f]azocine-5(6H)-pentanoic acid, 11,12-didehydro-δ-oxo-, 2,5-dioxo-1-pyrrolidinyl ester; 2,5-Dioxo-1-pyrrolidinyl 11,12-didehydro-δ-oxodibenz[b,f]azocine-5(6H)-pentanoate; DIBAC-NHS Ester; |
| Molecular form: | C24H20N2O5 |
| Appearance: | Solid |
| Mol. Weight: | 416.43 |
| Storage: | 2-8°C Refrigerator |
| Shipping Conditions: | Ambient |
| Applications: | DBCO-NHS ester 3 (Compound 12) is a cleavable linker that is used for making antibody-drug conjugate (ADC). DBCO-NHS ester 3 is a derivative of Dibenzylcyclooctyne (DBCO) obtained by activation of N-hydroxysuccinimide by the carboxylic acid moiety of both methyl-oxanorbornadiene (MeOND) and dibenzoazacyclooctyne (DIBAC)[1][2]. DBCO-NHS ester 3 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups |
DBCO-NHS ester 3
DBCO-NHS ester 3
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