| Catalogue number: | PA 27 0031414 |
| Chemical name: | Sulfo-DGN462 sodium |
CAS Number: |
1401203-09-5 |
| Category: | miscellaneous compounds,Antibody Drug Conjugate |
| Synonyms: | (12aS)-9-((3-((2-mercapto-2-methylpropyl)(2-(2-(2-methoxyethoxy)ethoxy)ethyl)amino)-5-((((S)-8-methoxy-6-oxo-11,12,12a,13-tetrahydro-6H-benzo[5,6][1,4]diazepino[1,2-a]indol-9-yl)oxy)methyl)benzyl)oxy)-8-methoxy-6-oxo-11,12,12a,13-tetrahydro-6H-benzo[5,6][1,4]diazepino[1,2-a]indole-12-sulfonic acid, sodium salt; 6H-Indolo[2,1-c][1,4]benzodiazepine-12-sulfonic acid, 11,12,12a,13-tetrahydro-9-[[3-[(2-mercapto-2-methylpropyl)[2-[2-(2-methoxyethoxy)ethoxy]ethyl]amino]-5-[[[(12aS)-11,12,12a,13-tetrahydro-8-methoxy-6-oxo-6H-indolo[2,1-c][1,4]benzodiazepin-9-yl]oxy]methyl]phenyl]methoxy]-8-methoxy-6-oxo-, sodium salt (1:1), (12aS)-; |
| Molecular form: | C53H61N5NaO12S2 |
| Appearance: | NA |
| Mol. Weight: | 1047.20 |
| Storage: | 2-8°C Refrigerator |
| Shipping Conditions: | Ambient |
| Applications: | sulfo-DGN462 sodium is degraded to DGN462 in culture medium and plasma. DGN462, a potent DNA-alkylating agent, shows anti-tumor activity, such as acute myeloid leukemia (AML) |
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