| Catalogue number: | PA 27 0031438 |
| Chemical name: | Cyclooctyne-O-NHS ester |
CAS Number: |
1425803-45-7 |
| Category: | miscellaneous compounds,Antibody Drug Conjugate |
| Synonyms: | Acetic acid, 2-(2-cyclooctyn-1-yloxy)-, 2,5-dioxo-1-pyrrolidinyl ester; 2,5-Dioxo-1-pyrrolidinyl 2-(2-cyclooctyn-1-yloxy)acetate; 2,5-Dioxopyrrolidin-1-yl 2-(cyclooct-2-ynyloxy)acetate; |
| Molecular form: | C14H17NO5 |
| Appearance: | Solid |
| Mol. Weight: | 279.29 |
| Storage: | 2-8°C Refrigerator |
| Shipping Conditions: | Ambient |
| Applications: | Cyclooctyne-O-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Cyclooctyne-O-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups |
Cyclooctyne-O-NHS ester
Cyclooctyne-O-NHS ester
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