| Catalogue number: | PA STI 089003 |
| Chemical name: | Olaparib-D4 |
CAS Number: |
2143107-55-3 |
| Category: | stable isotopes,Fine Chemicals,pharmaceutical standards,metabolites,impurities,intermediates |
| Synonyms: | 4-(3-(4-(Cyclopropane-1-carbonyl-d4)piperazine-1-carbonyl)-4-fluorobenzyl)phthalazin-1(2H)-one; 1(2H)-Phthalazinone, 4-[[3-[[4-(cyclopropyl-2,2,3,3-d4-carbonyl)-1-piperazinyl]carbonyl]-4-fluorophenyl]methyl]; 4-[[3-[[4-(Cyclopropyl-2,2,3,3-d4-carbonyl)-1-piperazinyl]carbonyl]-4-fluorophenyl]methyl]-1(2H)-phthalazinone; |
| Molecular form: | C24H19D4FN4O3 |
| Appearance: | White to Off-White Solid |
| Mol. Weight: | 438.5 |
| Storage: | 2-8°C Refrigerator |
| Shipping Conditions: | Ambient |
| Applications: | Isotope labelled Olaparib is a potent poly(ADP-ribose) polymerase (PARP) inhibitor. Olaparib has been shown to induce significant killing of ATM-deficient lymphoid tumor cells in vitro and in vivo. Recent studies show that Olaparib increases radiosensitivity of a lung tumor xenograft, making it a potential candidate for use in combination with radiotherapy. Potent PARP inhibitor. |
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