Catalogue number: | PA 27 0033417 |
Chemical name: | PROTAC BRD4 Degrader-13 |
CAS Number: |
2417370-71-7 |
Category: | miscellaneous compounds,Antibody Drug Conjugate |
Synonyms: | NA |
Molecular form: | C68H85F2N11O17P2S2 |
Appearance: | NA |
Mol. Weight: | 1492.55 |
Storage: | 2-8°C Refrigerator |
Shipping Conditions: | Ambient |
Applications: | PROTAC BRD4 Degrader-13 (compound 9d) is a von Hippel-Lindau system-based PROTAC BRD4 degrader with a linker that can be coupled to ADC antibodies to form PACs (PROTAC-antibody Conjugates). PROTAC BRD4 Degrader-13 can be coupled to STEAP1 and CLL1 antibodies to degrade BRD4 protein in PC3 prostate cancer cells with DC50 values of 0.025 nM and 6.0 nM, respectively |
PROTAC BRD4 Degrader-13
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