Catalogue number: | PA 27 0033085 |
Chemical name: | MYX1715 |
CAS Number: |
2445448-66-6 |
Category: | miscellaneous compounds,Antibody Drug Conjugate |
Synonyms: | 4-(2-(2-(3-(2-Aminoethyl)imidazo[1,2-a]pyridin-6-yl)-5-chlorophenoxy)ethyl)-N,N,1,5-tetramethyl-1H-pyrazole-3-carboxamide; 1H-Pyrazole-3-carboxamide, 4-[2-[2-[3-(2-aminoethyl)imidazo[1,2-a]pyridin-6-yl]-5-chlorophenoxy]ethyl]-N,N,1,5-tetramethyl-; 4-[2-[2-[3-(2-Aminoethyl)imidazo[1,2-a]pyridin-6-yl]-5-chlorophenoxy]ethyl]-N,N,1,5-tetramethyl-1H-pyrazole-3-carboxamide; |
Molecular form: | C25H29ClN6O2 |
Appearance: | Solid |
Mol. Weight: | 481 |
Storage: | 2-8°C Refrigerator |
Shipping Conditions: | Ambient |
Applications: | MYX1715 is an inhibitor of N-Myristoyltransferase (NMT) with a KD value of 0.09 nM. MYX1715 inhibits the proliferation of LU0884 and LU2511 with IC50 values of 44 nM and 9 nM. MYX1715 exhibits antitumor efficacy against neuroblastoma and gastric cancer in mouse models. MYX1715 can be used as ADC toxin |
MYX1715
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