Catalogue number: | PA 27 0033129 |
Chemical name: | Tert-butyl 3-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)propanoate |
CAS Number: |
252881-73-5 |
Category: | miscellaneous compounds,Antibody Drug Conjugate |
Synonyms: | Propanoic acid, 3-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]-, 1,1-dimethylethyl Ester; 1,1-Dimethylethyl 3-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]propanoate; |
Molecular form: | C13H25N3O5 |
Appearance: | Liquid |
Mol. Weight: | 303.36 |
Storage: | 2-8°C Refrigerator |
Shipping Conditions: | Ambient |
Applications: | N3-PEG3-CH2CH2-Boc is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. N3-PEG3-CH2CH2-Boc is also a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[2]. N3-PEG3-CH2CH2-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups |
Tert-butyl 3-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)propanoate
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