| Catalogue number: | PA 27 0033121 |
| Chemical name: | 8-Azido-octanoyl-Osu |
CAS Number: |
2576471-56-0 |
| Category: | miscellaneous compounds,Antibody Drug Conjugate |
| Synonyms: | 2,5-Dioxopyrrolidin-1-yl 8-azidooctanoate; Octanoic acid, 8-azido-, 2,5-dioxo-1-pyrrolidinyl Ester; 2,5-Dioxo-1-pyrrolidinyl 8-azidooctanoate; |
| Molecular form: | C12H18N4O4 |
| Appearance: | NA |
| Mol. Weight: | 282.3 |
| Storage: | 2-8°C Refrigerator |
| Shipping Conditions: | Ambient |
| Applications: | Mal-Val-Ala-PAB-N(SO2Me)-Exatecan (Compound LE14) is a conjugate of an ADC toxin Exatecan (HY-13631) and a linker Mal-Val-Ala-PAB-N(SO2Me). Mal-Val-Ala-PAB-N(SO2Me)-Exatecan can be used for synthesis of ADC FZ-AD005. FZ-AD005 is a delta-like ligand 3 (DLL3, KD=58.3 pM) targeting ADC, that exhibits antitumor efficacy against SCLC cancer |
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