(11aS,11a'S)-8,8'-(Pentane-1,5-diylbis(oxy))bis(7-methoxy-2-methylene-1,2,3,11a-tetrahydro-5H-benzo[e]pyrrolo[1,2-a][1,4]diazepin-5-one)

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Catalogue number:	PA 27 0033105
Chemical name:	(11aS,11a'S)-8,8'-(Pentane-1,5-diylbis(oxy))bis(7-methoxy-2-methylene-1,2,3,11a-tetrahydro-5H-benzo[e]pyrrolo[1,2-a][1,4]diazepin-5-one)
CAS Number:	260417-62-7
Category:	miscellaneous compounds,Antibody Drug Conjugate
Synonyms:	5H-Pyrrolo[2,1-c][1,4]benzodiazepin-5-one, 8,8′-[1,5-pentanediylbis(oxy)]bis[1,2,3,11a-tetrahydro-7-methoxy-2-methylene-, (11aS,11′aS)-; (11aS,11′aS)-8,8′-[1,5-Pentanediylbis(oxy)]bis[1,2,3,11a-tetrahydro-7-methoxy-2-methylene-5H-pyrrolo[2,1-c][1,4]benzodiazepin-5-one]; DRG 16; SG 2057; SG2057;
Molecular form:	C₃₃H₃₆N₄O₆
Appearance:	Solid
Mol. Weight:	584.67
Storage:	2-8°C Refrigerator
Shipping Conditions:	Ambient
Applications:	SG2057 (DRG16) is a PBD dimer containing a pentyldioxy linkage which binds sequence selectively in the minor groove of DNA forming DNA interstrand and intrastrand cross-linked adducts. SG2057 is a highly active antitumor agent