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Catalogue number: PA 27 0033100
Chemical name: PTAD-PEG4-N3

CAS Number:

2639395-40-5

Category: miscellaneous compounds,Antibody Drug Conjugate
Synonyms:

1-Azido-N-(2-(4-(3,5-dioxo-1,2,4-triazolidin-4-yl)-2-methoxyphenoxy)ethyl)-3,6,9,12-tetraoxapentadecan-15-amide; 4,7,10,13-Tetraoxapentadecanamide, 15-azido-N-[2-[4-(3,5-dioxo-1,2,4-triazolidin-4-yl)-2-methoxyphenoxy]ethyl]-; 15-Azido-N-[2-[4-(3,5-dioxo-1,2,4-triazolidin-4-yl)-2-methoxyphenoxy]ethyl]-4,7,10,13-tetraoxapentadecanamide;

Molecular form: C22H33N7O9
Appearance: Oil
Mol. Weight: 539.55
Storage: 2-8°C Refrigerator
Shipping Conditions: Ambient
Applications: PTAD-PEG4-N3 is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. PTAD-PEG4-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups

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