DC10SMe

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Catalogue number:	PA 27 0033095
Chemical name:	DC10SMe
CAS Number:	2649727-40-0
Category:	miscellaneous compounds,Antibody Drug Conjugate
Synonyms:	5-(3-(Methyldisulfaneyl)propanamido)-N-(2-((9aS)-4-oxo-2,4,9,9a-tetrahydro-1H-benzo[e]cyclopropa[c]indole-2-carbonyl)-1H-indol-5-yl)-1H-indole-2-carboxamide; 1H-Indole-2-carboxamide, N-[2-[[(9aS)-9,9a-dihydro-4-oxo-1H-benzo[e]cycloprop[c]indol-2(4H)-yl]carbonyl]-1H-indol-5-yl]-5-[[3-(methyldithio)-1-oxopropyl]amino]-; N-[2-[[(9aS)-9,9a-Dihydro-4-oxo-1H-benzo[e]cycloprop[c]indol-2(4H)-yl]carbonyl]-1H-indol-5-yl]-5-[[3-(methyldithio)-1-oxopropyl]amino]-1H-indole-2-carboxamide;
Molecular form:	C₃₅H₂₉N₅O₄S₂
Appearance:	NA
Mol. Weight:	647.77
Storage:	2-8°C Refrigerator
Shipping Conditions:	Ambient
Applications:	DC10SMe is a DNA alkylator, can be used in the synthesis of antibody-drug conjugate (ADC). DC10SMe exhibits IC50s of 15 pM, 12 pM, and 12 pM for Ramos, Namalwa, and HL60/s cancer cells, respectively