Catalogue number: | PA 27 0033096 |
Chemical name: | BCN-endo-PEG2-maleimide |
CAS Number: |
2675364-08-4 |
Category: | miscellaneous compounds,Antibody Drug Conjugate |
Synonyms: | ((1R,8S,9s)-Bicyclo[6.1.0]non-4-yn-9-yl)methyl (2-(2-(2-(3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamido)ethoxy)ethoxy)ethyl)carbamate; 5,8-Dioxa-2,11-diazatetradecanoic acid, 14-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-12-oxo-, (1α,8α,9β)-bicyclo[6.1.0]non-4-yn-9-ylmethyl Ester; (1α,8α,9β)-Bicyclo[6.1.0]non-4-yn-9-ylmethyl 14-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-12-oxo-5,8-dioxa-2,11-diazatetradecanoate; |
Molecular form: | C24H33N3O7 |
Appearance: | Oil |
Mol. Weight: | 475.54 |
Storage: | 2-8°C Refrigerator |
Shipping Conditions: | Ambient |
Applications: | BCN-endo-PEG2-maleimide is an ADC Linker containing 4 PEG units. BCN-endo-PEG2-maleimide contains the lyophilic bidentate macrocyclic ligand endo-BCN, which can further synthesize macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies |
BCN-endo-PEG2-maleimide
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