| Catalogue number: | PA 27 0033301 |
| Chemical name: | PROTAC BRD4 Degrader-5-CO-PEG3-N3 |
CAS Number: |
2704602-92-4 |
| Category: | miscellaneous compounds,Antibody Drug Conjugate |
| Synonyms: | (3R,5S)-1-((S)-2-(Tert-butyl)-17-((S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-4,16-dioxo-6,9,12-trioxa-3,15-diazaheptadecanoyl)-5-(((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)carbamoyl)pyrrolidin-3-yl 2-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)acetate; |
| Molecular form: | C58H75ClN12O12S2 |
| Appearance: | Solid |
| Mol. Weight: | 1231.88 |
| Storage: | 2-8°C Refrigerator |
| Shipping Conditions: | Ambient |
| Applications: | PROTAC BRD4 Degrader-5-CO-PEG3-N3 (Compound 2) is a PROTAC-linker Conjugate for PAC, comprises the BRD4 degrader GNE-987 and PEG-based linker[1]. PROTAC BRD4 Degrader-5-CO-PEG3-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups |
PROTAC BRD4 Degrader-5-CO-PEG3-N3
PROTAC BRD4 Degrader-5-CO-PEG3-N3
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