Catalogue number: | PA 27 0016671 |
Chemical name: | SMAD3 Inhibtor, SIS 3 |
CAS Number: |
1009104-85-1 |
Category: | miscellaneous compounds |
Synonyms: | 1-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-3-(1-methyl-2-phenylpyrrolo[2,3-b]pyridin-3-yl)prop-2-en-1-one; |
Molecular form: | C28H27N3O3 |
Appearance: | NA |
Mol. Weight: | 453.54 |
Storage: | 2-8°C Refrigerator |
Shipping Conditions: | Ambient |
Applications: | SMAD3 Inhibitor, SIS3 selectively inhibits TGF-B and activin. It has been shown to reduce TGF-B1-induced type 1 procollagen expression and myofibroblast differentiation in normal dermal fibroblasts as well as scleroderma fibroblasts. |
BTM: | NA |
SMAD3 Inhibtor, SIS 3
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