| Catalogue number: | PA PEP 001540 |
| Chemical name: | Sandramycin |
CAS Number: |
100940-65-6 |
| Category: | peptides,Antibody Drug Conjugate |
| Synonyms: | N,N'-(11,30-diisopropyl-12,15,31,34-tetramethyl-6,10,13,16,19,25,29,32,35,38-decaoxodotriacontahydro-2H,6H,10H,25H-dipyrido[2,1-b1:2',1'-l][1,17]dioxa[4,7,10,13,20,23,26,29]octaazacyclodotriacontine-7,26-diyl)bis(3-hydroxyquinoline-2-carboxamide); L-Valine, N-[(3-hydroxy-2-quinolinyl)carbonyl]-D-seryl-(2S)-2-piperidinecarbonylglycyl-N-methylglycyl-N-methyl-, bimol. (5→1′3),(5′→13)-dilactone; 2H,6H,10H,25H-Dipyrido[2,1-l:2′,1′-b1][1,17,4,7,10,13,20,23,26,29]dioxaoctaazacyclodotriacontine, cyclic peptide deriv; (-)-Sandramycin; |
| Molecular form: | C60H76N12O16 |
| Appearance: | NA |
| Mol. Weight: | 1221.34 |
| Storage: | 2-8°C Refrigerator |
| Shipping Conditions: | Ambient |
| Applications: | Sandramycin ia a cyclic depsipeptide antibiotic isolated from cultured broth of a Nocardioides sp. Sandramycin is also a DNA intercalator that potently binds DNA and is an ADC cytotoxin. Sandramycin is active against Gram-positive bacteria and has potent antitumor activity |
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