| Catalogue number: | PA 18 35000 |
| Chemical name: | Regorafenib Monohydrate |
CAS Number: |
1019206-88-2 |
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| Category: | aromatics,heterocycles,metabolites,impurities,pharmaceutical standards,intermediates,Fine Chemicals,fluorescent labels and indicators |
| Synonyms: | 4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-2-pyridinecarboxamide Monohydrate; 4-[4-[N'-(4-Chloro-3-trifluoromethylphenyl)ureido]-3- fluorophenoxy]pyridine-2-carboxylic Acid Methylamide Monohydrate; 4-(4-(3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)-N-methylpicolinamide Hydrate; 4-[4-({[4-Chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)-3-fluorophenoxy]-N-methylpyridine-2-carboxamide Hydrate; 2-Pyridinecarboxamide, 4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-, monohydrate; 4-[4-({[4-Chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)-3-fluorophenoxy]-N-methylpyridine-2-carboxamide monohydrate (USP); |
| Molecular form: | C21H17ClF4N4O4 |
| Appearance: | Light Pink Solid |
| Mol. Weight: | 500.83 |
| Storage: | 2-8°C Refrigerator |
| Shipping Conditions: | Ambient |
| Applications: | A monohydrate salt of Regorafenib, a multikinase inhibitor used in the treatment of metastatic colorectal cancer and advanced gastrointestinal stromal tumors. Shows anti-angiogenic activity due to its dual targeted VEGFR2-TIE2 tyrosine kinase inhibition. |
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