| Catalogue number: | PA 27 0020702 |
| Chemical name: | 2-[[4-([1,1'-biphenyl]-4-ylamino)-6-chloro-2-pyrimidinyl]thio]octanoic acid |
CAS Number: |
1077626-51-7 |
| Category: | miscellaneous compounds |
| Synonyms: | 2-((4-([1,1'-Biphenyl]-4-ylamino)-6-chloropyrimidin-2-yl)thio)octanoic acid; |
| Molecular form: | C24H26ClN3O2S |
| Appearance: | NA |
| Mol. Weight: | 456 |
| Storage: | 2-8°C Refrigerator |
| Shipping Conditions: | Ambient |
| Applications: | A potent, reversible inhibitor of 5-lipoxygenase, blocking leukotriene synthesis with an IC50 value of 0.7 μM in intact human polymorphonuclear leukocytes. It also attenuates leukotriene B4 synthesis, prevents carrageenan-induced pleurisy, and protects against platelet-activating factor-induced shock in mice when given intraperitoneally. |
2-[[4-([1,1'-biphenyl]-4-ylamino)-6-chloro-2-pyrimidinyl]thio]octanoic acid
2-[[4-([1,1'-biphenyl]-4-ylamino)-6-chloro-2-pyrimidinyl]thio]octanoic acid
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