| Catalogue number: | PA 27 0030808 |
| Chemical name: | Triethylene Glycol 2-Bromoethyl Methyl Ether |
CAS Number: |
110429-45-3 |
| Category: | miscellaneous compounds,Antibody Drug Conjugate |
| Synonyms: | 2,5,8,11-Tetraoxatridecane, 13-bromo-; 13-Bromo-2,5,8,11-tetraoxatridecane; 1-[2-[2-(2-Bromoethoxy)ethoxy]ethoxy]-2-methoxyethane; 1-Bromo-3,6,9,12-tetraoxatridecane; 2-[2-[2-(2-Methoxyethoxy)ethoxy]ethoxy]ethyl bromide; Triethylene glycol mono(2-bromoethyl) ether methyl ether; |
| Molecular form: | C9H19BrO4 |
| Appearance: | Liquid |
| Mol. Weight: | 271.15 |
| Storage: | 2-8°C Refrigerator |
| Shipping Conditions: | Ambient |
| Applications: | m-PEG4-Br is a cleavable ADC linker used in the synthesis of antibody-drug conjugate (ADC) for Trastuzumab (HY-P9907). m-PEG4-Br is placed distally from the monomethyl auristatin E (MMAE) payload to yield an ADC with altered hydrophilicity, antigen binding, and in vitro potency[1]. m-PEG4-Br also can be used as a PROTAC linker that can be used in the synthesis of PROTACs. |
Triethylene Glycol 2-Bromoethyl Methyl Ether
Triethylene Glycol 2-Bromoethyl Methyl Ether
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