| Catalogue number: | PA 27 0017662 |
| Chemical name: | Combretastatin A4 |
CAS Number: |
117048-59-6 |
| Category: | miscellaneous compounds |
| Synonyms: | (Z)-2-Methoxy-5-(3,4,5-trimethoxystyryl)phenol; |
| Molecular form: | C18H20O5 |
| Appearance: | Off-White to Pale Beige Solid |
| Mol. Weight: | 316.35 |
| Storage: | 2-8°C Refrigerator |
| Shipping Conditions: | Ambient |
| Applications: | Combretastatin is a small organic molecule found in the bark of the African bush willow tree Combretum caffrum. Combretastatin-A4 Prodrug Induces Mitotic Catastrophe in Chronic Lymphocytic Leukemia Cell Line Independent of Caspase Activation and Poly(ADP-ribose) Polymerase Cleavage. A potent cytotoxic agent which strongly inhibits the polymerization of tubulin by binding to the colchicine site. |
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