| Catalogue number: | PA 27 0021140 |
| Chemical name: | (R)-(+)-Blebbistatin |
CAS Number: |
1177356-70-5 |
| Category: | miscellaneous compounds |
| Synonyms: | (R)-3a-Hydroxy-6-methyl-1-phenyl-1,2,3,3a-tetrahydro-4H-pyrrolo[2,3-b]quinolin-4-one; |
| Molecular form: | C18H16N2O2 |
| Appearance: | Yellow Solid |
| Mol. Weight: | 292.34 |
| Storage: | 2-8°C Refrigerator |
| Shipping Conditions: | Ambient |
| Applications: | (R)-(+)-Blebbistatin is a 1-phenyl-2-pyrrolidinone derivative and a selective inhibitor of non-muscle myosin II (1, 2, 3). It blocks cell blebbing rapidly and reversibly and also disrupts directed cell migration and cytokinesis in vertebrate cell. (R)-(+)-Blebbistatin can also inhibit contraction of the cleavage furrow without disrupting mitosis or contractile ring assembly. (R)-(+)-Blebbistatin is suitable as a negative control for (S)-(-)-Blebblastatin. |
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