| Catalogue number: | PA 27 0021208 |
| Chemical name: | PF 184 |
CAS Number: |
1187460-81-6 |
| Category: | miscellaneous compounds |
| Synonyms: | 8-(2-((3S,4R)-3,4-Bis(hydroxymethyl)-3,4-dimethylpyrrolidin-1-yl)-5-chloroisonicotinamido)-1-(4-fluorophenyl)-4,5-dihydro-1H-benzo[g]indazole-3-carboxamide; |
| Molecular form: | C32H32ClFN6O4 |
| Appearance: | NA |
| Mol. Weight: | 619.09 |
| Storage: | 2-8°C Refrigerator |
| Shipping Conditions: | Ambient |
| Applications: | PF 184 is a potent and selective IKK-2 inhibitor (IC50 = 37 nM). Displays selectivity over 85 other kinases. Inhibits IL-1β-induced TNF-α in a steroid-insensitive in vitro model of oxidative stress. |
PF 184
PF 184
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