| Catalogue number: | PA 27 0030831 |
| Chemical name: | (R)-8-Azido-2-(Fmoc-amino)octanoic acid |
CAS Number: |
1191429-18-1 |
| Category: | miscellaneous compounds,Antibody Drug Conjugate |
| Synonyms: | Octanoic acid, 8-azido-2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-, (2R)-; (2R)-8-Azido-2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]octanoic acid; (R)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-8-azidooctanoic acid; |
| Molecular form: | C23H26N4O4 |
| Appearance: | NA |
| Mol. Weight: | 422.49 |
| Storage: | 2-8°C Refrigerator |
| Shipping Conditions: | Ambient |
| Applications: | (R)-8-Azido-2-(Fmoc-amino)octanoic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. (R)-8-Azido-2-(Fmoc-amino)octanoic acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups |
(R)-8-Azido-2-(Fmoc-amino)octanoic acid
(R)-8-Azido-2-(Fmoc-amino)octanoic acid
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