Biotin-PEG1-azide

In House Impurity

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Catalogue number:	PA 02 0751043
Chemical name:	Biotin-PEG1-azide
CAS Number:	1204085-48-2
Category:	intermediates,pharmaceutical standards,Fine Chemicals,biotin derivatives,Antibody Drug Conjugate
Synonyms:	1H-Thieno[3,4-d]imidazole-4-pentanamide, N-[2-(2-azidoethoxy)ethyl]hexahydro-2-oxo-, (3aS,4S,6aR)-; (3aS,4S,6aR)-N-[2-(2-Azidoethoxy)ethyl]hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanamide;
Molecular form:	C₁₄H₂₄N₆O₃S
Appearance:	Oil
Mol. Weight:	356.45
Storage:	2-8°C Refrigerator
Shipping Conditions:	Ambient
Applications:	Biotin-PEG1-azide is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Biotin-PEG1-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups