| Catalogue number: | PA 03 0741001 |
| Chemical name: | Colchicine Methanethiosulfonate |
CAS Number: |
1217821-52-7 |
| Category: | chiral standards,enzyme inhibitors,enzyme activators,sulphur and selenium compounds,pharmaceutical standards,impurities,metabolites,fine chemicals |
| Synonyms: | (S)-S-(3-oxo-3-((1,2,3,10-Tetramethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl)amino)propyl) methanesulfonothioate; |
| Molecular form: | C24H29NO8S2 |
| Appearance: | Pale Yellow to Light Yellow Solid |
| Mol. Weight: | 523.62 |
| Storage: | 2-8°C Refrigerator |
| Shipping Conditions: | Ambient |
| Applications: | The methanethiosulfonate derfivative of Colchicine, an antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin. Induces apoptosis in several normal and tumor cell lines and activates the JNK/SAPK signaling pathway. |
| BTM: | NA |
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