| Catalogue number: | PA STI 074230 |
| Chemical name: | Plerixafor-d4 |
CAS Number: |
1246819-87-3 |
| Category: | aromatics,heterocycles,enzyme inhibitors,stable isotopes,pharmaceutical standards,intermediates,Fine Chemicals |
| Synonyms: | 1,1'-[1,4-Phenylenebis(methylene)]bis[4,8,11-tris(trifluoroacetyl)-1,4,8,11-tetraazacyclotetradecane-d4; |
| Molecular form: | C28H50D4N8 |
| Appearance: | Off-White Solid |
| Mol. Weight: | 506.81 |
| Storage: | 2-8°C Hygroscopic, Refrigerator, Under Inert Atmosphere |
| Shipping Conditions: | Ambient |
| Applications: | Labelled Plerixafor, it is a hematopoietic stem cell (HSC) mobilizer that inhibits the CXCR4 chemokine receptor and blocks binding of its ligand, stromal cell-derived factor-1-α (SDF-1-α).This agent was approved on Dec. 15, 2008, as treatment in combination with granulocyte-colony stimulating factor (G-CSF) to mobilize HSCs to the peripheral blood for collection and subsequent autologous transplantation in patients with non-Hodgkin's lymphoma (NHL) and multiple myeloma (MM). |
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